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The map label for this gene is tatD [H]

Identifier: 157963611

GI number: 157963611

Start: 4612388

End: 4613182

Strand: Direct

Name: tatD [H]

Synonym: Spea_3799

Alternate gene names: 157963611

Gene position: 4612388-4613182 (Clockwise)

Preceding gene: 157963610

Following gene: 157963612

Centisome position: 89.14

GC content: 45.79

Gene sequence:

>795_bases
ATGCCAGAATATATGGATATAGCTGTCAACCTAGTTGGCAGCTCGCTTGAAAAAGACATTCAGCGAGTCGTCGATGATGC
AGCGGCTCAGTCAGTCACCTCCATGGTGATTATTGGCAGTCACATCCAAGAGAGTGAACAGGCCATCAGTCTGTGTGAGC
AGTTCCCAGGACAACTCTATTGTACCGCAGGTATTCACCCTCATCACGCCAGTGAATGGCAAACAGACAGTGCAGATATA
TTACGAAAATTAACCCTTTCTCCGAGCGTGATCGCTGTGGGCGAATGTGGTTTAGATTATAATCGCGACTTCTCCCCCAG
AGATATGCAGCGCAAGGCATTTGCAGAGCAGTTGGCACTAGCCGTAGAACTCAAAATGCCTGTATTAATGCATGAGCGTG
ATGCCCATGATGATTTCCTAGCAATTCTAAAAGAATACCGTTCTGACCTGCCAGCGGCTCTGTTGCATTGCTTTACAGGC
AATAAACAATCTCTCGATGCATATATAGAGTTGGATCTGTATTTAGGGGTGACGGGTTGGGTCTGCGATGAGCGCAGAGG
ACAAGAGCTAGCATCGCTCGTGCCTCACATTCCAGATGAGCGGATCTTGATTGAAACAGATAGCCCATACCTATTACCAA
GAAGCATGCGCCCGAAACCAAAATCCAGTAAAAATGAACCTAAATATCTGCCATATATTGCTCAGTATGTTGCCGCTCTC
AGACAGCAAAATATTAATGACTTTGCAGAGACAAGCTACAGAAATAGCCGTCGGTTCTTTGGTTTAGAGTATTAA

Upstream 100 bases:

>100_bases
AAGCAGAACAAACCGTCTATATAGAAAAAGCGGCATTAGGATCTTTCATGCTAGGCTCAGATGATCGCAATACAACCATT
AGAGTAAAACGTTTAAAGTA

Downstream 100 bases:

>100_bases
TGAAGGCCAAGCTTCTGCAACTTGTCCTTACCACATTATTGCTATTCTCTGGCTTAGTAACAGCTGGAGACCCCCTCATT
ATTACTAAGCATAGCGACGA

Product: TatD-like deoxyribonuclease

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPEYMDIAVNLVGSSLEKDIQRVVDDAAAQSVTSMVIIGSHIQESEQAISLCEQFPGQLYCTAGIHPHHASEWQTDSADI
LRKLTLSPSVIAVGECGLDYNRDFSPRDMQRKAFAEQLALAVELKMPVLMHERDAHDDFLAILKEYRSDLPAALLHCFTG
NKQSLDAYIELDLYLGVTGWVCDERRGQELASLVPHIPDERILIETDSPYLLPRSMRPKPKSSKNEPKYLPYIAQYVAAL
RQQNINDFAETSYRNSRRFFGLEY

Sequences:

>Translated_264_residues
MPEYMDIAVNLVGSSLEKDIQRVVDDAAAQSVTSMVIIGSHIQESEQAISLCEQFPGQLYCTAGIHPHHASEWQTDSADI
LRKLTLSPSVIAVGECGLDYNRDFSPRDMQRKAFAEQLALAVELKMPVLMHERDAHDDFLAILKEYRSDLPAALLHCFTG
NKQSLDAYIELDLYLGVTGWVCDERRGQELASLVPHIPDERILIETDSPYLLPRSMRPKPKSSKNEPKYLPYIAQYVAAL
RQQNINDFAETSYRNSRRFFGLEY
>Mature_263_residues
PEYMDIAVNLVGSSLEKDIQRVVDDAAAQSVTSMVIIGSHIQESEQAISLCEQFPGQLYCTAGIHPHHASEWQTDSADIL
RKLTLSPSVIAVGECGLDYNRDFSPRDMQRKAFAEQLALAVELKMPVLMHERDAHDDFLAILKEYRSDLPAALLHCFTGN
KQSLDAYIELDLYLGVTGWVCDERRGQELASLVPHIPDERILIETDSPYLLPRSMRPKPKSSKNEPKYLPYIAQYVAALR
QQNINDFAETSYRNSRRFFGLEY

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=293, Percent_Identity=29.6928327645051, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI225903439, Length=250, Percent_Identity=31.2, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI225903424, Length=202, Percent_Identity=31.1881188118812, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=25.3731343283582, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=25.3731343283582, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=25.1824817518248, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=25.3846153846154, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=25.9911894273128, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=45.7692307692308, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787342, Length=251, Percent_Identity=30.6772908366534, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082439, Length=249, Percent_Identity=26.9076305220884, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=35.8156028368794, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=26.4925373134328, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=223, Percent_Identity=28.6995515695067, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=223, Percent_Identity=28.6995515695067, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648690, Length=282, Percent_Identity=30.8510638297872, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI221330018, Length=301, Percent_Identity=27.5747508305648, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24586117, Length=277, Percent_Identity=28.5198555956679, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29907; Mature: 29776

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYMDIAVNLVGSSLEKDIQRVVDDAAAQSVTSMVIIGSHIQESEQAISLCEQFPGQLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
CTAGIHPHHASEWQTDSADILRKLTLSPSVIAVGECGLDYNRDFSPRDMQRKAFAEQLAL
EECCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
AVELKMPVLMHERDAHDDFLAILKEYRSDLPAALLHCFTGNKQSLDAYIELDLYLGVTGW
HHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCE
VCDERRGQELASLVPHIPDERILIETDSPYLLPRSMRPKPKSSKNEPKYLPYIAQYVAAL
ECCCHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RQQNINDFAETSYRNSRRFFGLEY
HHCCCHHHHHHHHCCCCCEECCCC
>Mature Secondary Structure 
PEYMDIAVNLVGSSLEKDIQRVVDDAAAQSVTSMVIIGSHIQESEQAISLCEQFPGQLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
CTAGIHPHHASEWQTDSADILRKLTLSPSVIAVGECGLDYNRDFSPRDMQRKAFAEQLAL
EECCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
AVELKMPVLMHERDAHDDFLAILKEYRSDLPAALLHCFTGNKQSLDAYIELDLYLGVTGW
HHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCE
VCDERRGQELASLVPHIPDERILIETDSPYLLPRSMRPKPKSSKNEPKYLPYIAQYVAAL
ECCCHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RQQNINDFAETSYRNSRRFFGLEY
HHCCCHHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]