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The map label for this gene is cph2 [H]

Identifier: 157963612

GI number: 157963612

Start: 4613182

End: 4615047

Strand: Direct

Name: cph2 [H]

Synonym: Spea_3800

Alternate gene names: 157963612

Gene position: 4613182-4615047 (Clockwise)

Preceding gene: 157963611

Following gene: 157963613

Centisome position: 89.15

GC content: 42.12

Gene sequence:

>1866_bases
ATGAAGGCCAAGCTTCTGCAACTTGTCCTTACCACATTATTGCTATTCTCTGGCTTAGTAACAGCTGGAGACCCCCTCAT
TATTACTAAGCATAGCGACGACAAAATTGAGCTAACATCCCAACTCTATATTACCCATGTGAATGCCACTATCGAACGGC
TCGTGAACCCAGCCGTTCGATGGCAAAAATATGAACCAAAAGCGATGCTGGGCATTGGAGAAAAAGCCTATTGGGTTAGG
TTATCCCTTAGCTATGAATCAGGTGTTTCTAGGCAGCAAATTATATCTATCGCAAATCCACATTTAGATCATATCGAGTT
TTATCACTTCAGTGGCCCTACGCTGCTTAAACAATTACGAGCAGGCGACAGTTTGCCTTTCAACCAAAGGCCTATTATAA
GCACTCATTTTCTGTACTCGTTTAATAACCACCAACAAGATAGCCATGATTTCTATTTGCGAGTGAAAACGTCCGGAACA
TTTAGCATACCGATGACCCTCTGGACTATCGATTCCTACTACCAAAATGCCGAACGACATTCGGTCTTTTATGGTTTTCA
GATTGGCGTGTTAATAGCCATTGGTATCTTTAGCCTGTTAATCGCTGTGACTTCTCATTCATTCAGTTATAGCTATTATG
CTGGTTTTGTACTCTCCATTACCCTTTTTGTTGCGAGCTTACACGGATTAGCATTTAGGTTTATCTGGCCAAATTTTCCG
AGCGTGCAAGAGTTTGCTTTGCCAGCCCTACTGAGCCTATCTATGATGTTTGCCTTCTTGTTCTCAGAGAAGGCAATGCA
CCTTAAGTACCACAATCAGACTATGCTGCGACTCTGTCGAGCTAGTGCCGCAATGTCTTTAGTGCTGCTTTTAAGCGGGT
TATTACTCAACTACTCAACTGCGTTAACGATCAATATTTACGCGGTAATGCTTTCCAGCATATTATTAATGTGCATGTCT
CTCGCCCAAGCTTTCAAAGGCAATAAGCTAGCAAAGTTCTTTGCTATAGGCTGGGCAGGTATGATGTTAGGGGCATTGAT
ATCTGGTGCTATATATCTAGGTTTGCTTCACTGGGACCTTCAAGCTAAAACTCCTTTTATGATTGGCCTAAGTTTAGAGG
TTGTTTTTATGGCAGCCCTACTCGCGATCCGCTATAACGATGAACGCCTAAATAAATTAAAAATACAGAAAGACGCACTC
ATTCAAGCAAATAAAGCACAGGAGACCAAAGAAGAGGCGTTACGCATCGAAGCTAGAAGTAGCGAAAAGTTATCTCAAAT
GGTTCAAGAACGCACCCTAGAACTAGAGATTGCCCTACGAGAACTCAATGAGGCAAATCAGAAACTCACCGAACAGACAA
GAGTAGACAGCCTGACAGGCGTTAAAAATCGCGCCTCATTCGATAAACGTATCATGGCCGAAGGTCGAATTAGTCGAAGA
CAGCAGACCCCATTATCAATTTTAATGCTGGATATCGATCGCTTTAAATTAATTAATGACTCCTATGGCCACCTAGCTGG
CGATCAAGCTTTACGCGTAATCGCCGATAAATTAAAAGAAACTTTAAAGCGACCAACCGATCTAGTGTCACGTTTTGGCG
GAGAGGAGTTTGCTATTATATTACCCAACACTGATAAAATAGGTGCACAGCAAGTAGCTGAGACGTTAAGGAAAGTTATC
TGCGAACTGCCTATTAGTTGGGGGGAAGACAGTATCCCTCTAACAGTTAGTATTGGGGTGAGTAGCGAAATTATTACCTC
AGAAGAACATACTACTTTATTATTAGAACAAGCAGATAAAGCACTTTATCAAGCAAAGAATGACGGGCGTAACCGAGTAA
GACTCTACAGCCCCGATCAAGATTAA

Upstream 100 bases:

>100_bases
ATATTGCTCAGTATGTTGCCGCTCTCAGACAGCAAAATATTAATGACTTTGCAGAGACAAGCTACAGAAATAGCCGTCGG
TTCTTTGGTTTAGAGTATTA

Downstream 100 bases:

>100_bases
TATCACCATCGTCTGGAGCCAAATGTGAATATTATTACTAGTGCCTACCCACAACGTAGAATGCGCCGTATGCGTAAACA
TGAGTTTAGTCGCCGTCTAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MKAKLLQLVLTTLLLFSGLVTAGDPLIITKHSDDKIELTSQLYITHVNATIERLVNPAVRWQKYEPKAMLGIGEKAYWVR
LSLSYESGVSRQQIISIANPHLDHIEFYHFSGPTLLKQLRAGDSLPFNQRPIISTHFLYSFNNHQQDSHDFYLRVKTSGT
FSIPMTLWTIDSYYQNAERHSVFYGFQIGVLIAIGIFSLLIAVTSHSFSYSYYAGFVLSITLFVASLHGLAFRFIWPNFP
SVQEFALPALLSLSMMFAFLFSEKAMHLKYHNQTMLRLCRASAAMSLVLLLSGLLLNYSTALTINIYAVMLSSILLMCMS
LAQAFKGNKLAKFFAIGWAGMMLGALISGAIYLGLLHWDLQAKTPFMIGLSLEVVFMAALLAIRYNDERLNKLKIQKDAL
IQANKAQETKEEALRIEARSSEKLSQMVQERTLELEIALRELNEANQKLTEQTRVDSLTGVKNRASFDKRIMAEGRISRR
QQTPLSILMLDIDRFKLINDSYGHLAGDQALRVIADKLKETLKRPTDLVSRFGGEEFAIILPNTDKIGAQQVAETLRKVI
CELPISWGEDSIPLTVSIGVSSEIITSEEHTTLLLEQADKALYQAKNDGRNRVRLYSPDQD

Sequences:

>Translated_621_residues
MKAKLLQLVLTTLLLFSGLVTAGDPLIITKHSDDKIELTSQLYITHVNATIERLVNPAVRWQKYEPKAMLGIGEKAYWVR
LSLSYESGVSRQQIISIANPHLDHIEFYHFSGPTLLKQLRAGDSLPFNQRPIISTHFLYSFNNHQQDSHDFYLRVKTSGT
FSIPMTLWTIDSYYQNAERHSVFYGFQIGVLIAIGIFSLLIAVTSHSFSYSYYAGFVLSITLFVASLHGLAFRFIWPNFP
SVQEFALPALLSLSMMFAFLFSEKAMHLKYHNQTMLRLCRASAAMSLVLLLSGLLLNYSTALTINIYAVMLSSILLMCMS
LAQAFKGNKLAKFFAIGWAGMMLGALISGAIYLGLLHWDLQAKTPFMIGLSLEVVFMAALLAIRYNDERLNKLKIQKDAL
IQANKAQETKEEALRIEARSSEKLSQMVQERTLELEIALRELNEANQKLTEQTRVDSLTGVKNRASFDKRIMAEGRISRR
QQTPLSILMLDIDRFKLINDSYGHLAGDQALRVIADKLKETLKRPTDLVSRFGGEEFAIILPNTDKIGAQQVAETLRKVI
CELPISWGEDSIPLTVSIGVSSEIITSEEHTTLLLEQADKALYQAKNDGRNRVRLYSPDQD
>Mature_621_residues
MKAKLLQLVLTTLLLFSGLVTAGDPLIITKHSDDKIELTSQLYITHVNATIERLVNPAVRWQKYEPKAMLGIGEKAYWVR
LSLSYESGVSRQQIISIANPHLDHIEFYHFSGPTLLKQLRAGDSLPFNQRPIISTHFLYSFNNHQQDSHDFYLRVKTSGT
FSIPMTLWTIDSYYQNAERHSVFYGFQIGVLIAIGIFSLLIAVTSHSFSYSYYAGFVLSITLFVASLHGLAFRFIWPNFP
SVQEFALPALLSLSMMFAFLFSEKAMHLKYHNQTMLRLCRASAAMSLVLLLSGLLLNYSTALTINIYAVMLSSILLMCMS
LAQAFKGNKLAKFFAIGWAGMMLGALISGAIYLGLLHWDLQAKTPFMIGLSLEVVFMAALLAIRYNDERLNKLKIQKDAL
IQANKAQETKEEALRIEARSSEKLSQMVQERTLELEIALRELNEANQKLTEQTRVDSLTGVKNRASFDKRIMAEGRISRR
QQTPLSILMLDIDRFKLINDSYGHLAGDQALRVIADKLKETLKRPTDLVSRFGGEEFAIILPNTDKIGAQQVAETLRKVI
CELPISWGEDSIPLTVSIGVSSEIITSEEHTTLLLEQADKALYQAKNDGRNRVRLYSPDQD

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral membrane protein (Potential) [C]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=34.2541436464088, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=35, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=40.7821229050279, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=34.4632768361582, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=37.1069182389937, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=36.8421052631579, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI145693134, Length=180, Percent_Identity=36.6666666666667, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=35.7541899441341, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788085, Length=159, Percent_Identity=30.8176100628931, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787541, Length=184, Percent_Identity=29.3478260869565, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787056, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=196, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788956, Length=180, Percent_Identity=34.4444444444444, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081974, Length=170, Percent_Identity=30, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081921, Length=178, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 70021; Mature: 70021

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKLLQLVLTTLLLFSGLVTAGDPLIITKHSDDKIELTSQLYITHVNATIERLVNPAVR
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEHHHHHHHHCCHHHH
WQKYEPKAMLGIGEKAYWVRLSLSYESGVSRQQIISIANPHLDHIEFYHFSGPTLLKQLR
CCCCCCCCEEECCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
AGDSLPFNQRPIISTHFLYSFNNHQQDSHDFYLRVKTSGTFSIPMTLWTIDSYYQNAERH
CCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCEEEECEEEEEEHHHHHCCHHC
SVFYGFQIGVLIAIGIFSLLIAVTSHSFSYSYYAGFVLSITLFVASLHGLAFRFIWPNFP
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
SVQEFALPALLSLSMMFAFLFSEKAMHLKYHNQTMLRLCRASAAMSLVLLLSGLLLNYST
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ALTINIYAVMLSSILLMCMSLAQAFKGNKLAKFFAIGWAGMMLGALISGAIYLGLLHWDL
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
QAKTPFMIGLSLEVVFMAALLAIRYNDERLNKLKIQKDALIQANKAQETKEEALRIEARS
CCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHEECHHHHHCCCCHHHHHHHHHEECCCC
SEKLSQMVQERTLELEIALRELNEANQKLTEQTRVDSLTGVKNRASFDKRIMAEGRISRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHC
QQTPLSILMLDIDRFKLINDSYGHLAGDQALRVIADKLKETLKRPTDLVSRFGGEEFAII
CCCCEEEEEEEHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEE
LPNTDKIGAQQVAETLRKVICELPISWGEDSIPLTVSIGVSSEIITSEEHTTLLLEQADK
ECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHH
ALYQAKNDGRNRVRLYSPDQD
HHHHHCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKAKLLQLVLTTLLLFSGLVTAGDPLIITKHSDDKIELTSQLYITHVNATIERLVNPAVR
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEHHHHHHHHCCHHHH
WQKYEPKAMLGIGEKAYWVRLSLSYESGVSRQQIISIANPHLDHIEFYHFSGPTLLKQLR
CCCCCCCCEEECCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHH
AGDSLPFNQRPIISTHFLYSFNNHQQDSHDFYLRVKTSGTFSIPMTLWTIDSYYQNAERH
CCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCEEEECEEEEEEHHHHHCCHHC
SVFYGFQIGVLIAIGIFSLLIAVTSHSFSYSYYAGFVLSITLFVASLHGLAFRFIWPNFP
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
SVQEFALPALLSLSMMFAFLFSEKAMHLKYHNQTMLRLCRASAAMSLVLLLSGLLLNYST
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ALTINIYAVMLSSILLMCMSLAQAFKGNKLAKFFAIGWAGMMLGALISGAIYLGLLHWDL
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
QAKTPFMIGLSLEVVFMAALLAIRYNDERLNKLKIQKDALIQANKAQETKEEALRIEARS
CCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHEECHHHHHCCCCHHHHHHHHHEECCCC
SEKLSQMVQERTLELEIALRELNEANQKLTEQTRVDSLTGVKNRASFDKRIMAEGRISRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHC
QQTPLSILMLDIDRFKLINDSYGHLAGDQALRVIADKLKETLKRPTDLVSRFGGEEFAII
CCCCEEEEEEEHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEEE
LPNTDKIGAQQVAETLRKVICELPISWGEDSIPLTVSIGVSSEIITSEEHTTLLLEQADK
ECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHH
ALYQAKNDGRNRVRLYSPDQD
HHHHHCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]