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The map label for this gene is oppF2 [H]

Identifier: 157963452

GI number: 157963452

Start: 4428728

End: 4429324

Strand: Reverse

Name: oppF2 [H]

Synonym: Spea_3640

Alternate gene names: 157963452

Gene position: 4429324-4428728 (Counterclockwise)

Preceding gene: 157963453

Following gene: 157963451

Centisome position: 85.6

GC content: 51.09

Gene sequence:

>597_bases
ATGCTAACGCTGCGTAATGCTTGTTTACGGCGCGGGGAGCAAAAGATCGCATTTCCCGATCTCAGCTTACAGTCTGGAGA
AGTGCTGGGTCTATCGGGCCCTAGCGGAGTGGGTAAGTCATCGTTAGCGAGTGTACTTGCGGGTATGGTTAAGGCCGATG
CCGAGCGCCTAGAACTGCCTACAATCTTGCCTAACCAAGCTAACCCGGTGCAATGGCTTATTCAGCAGAGTGAGTTTGCC
TTTAATCCACGGCTAACATTAAAGGCATCGCTCAACGAGAGCTGGAGAGGTGATGGTTATCTAGCTTTGTTGCAAGAATA
TGGTCTAGAGCAGAGCTGGTTAACGAGACGCCCGAATCAGTTATCTGGTGGGCAGTTGCAGCGATTTAACTTGATTAGGG
CGCTAGTGCCGACCACTGAGTATTTGATCTGTGATGAAGTGACCGCTCATCTGGACATGGTGACTCAAGCCCAATTCTGG
CAACAGCTTCTAGCGAGTGCCAAGCGTCGCAACTTAGCTCTCTTGGTGATCTCCCACGACGAGTACCTGCTCAACGCTAT
TTGTCATCGAGTCATCGAGTGGCCGTGTACTCGCTAA

Upstream 100 bases:

>100_bases
TTGGTTGAGATAACGACTAGTGCCAATATCCGCAGCGGAGCGTGCCATAGCTATACAAGAAGCTTATGGGCGGCGCTGCC
GGAGCATTGGGGAGTAACAG

Downstream 100 bases:

>100_bases
TCATTTAATCATCTTATGCCTTATGTAGCCGATGTTTATATAACAAGCAATTATTTAGGCTTGGTGAATATTTTTGAGTG
TGATTCCCACCTCAGTTTGC

Product: ABC transporter-like protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MLTLRNACLRRGEQKIAFPDLSLQSGEVLGLSGPSGVGKSSLASVLAGMVKADAERLELPTILPNQANPVQWLIQQSEFA
FNPRLTLKASLNESWRGDGYLALLQEYGLEQSWLTRRPNQLSGGQLQRFNLIRALVPTTEYLICDEVTAHLDMVTQAQFW
QQLLASAKRRNLALLVISHDEYLLNAICHRVIEWPCTR

Sequences:

>Translated_198_residues
MLTLRNACLRRGEQKIAFPDLSLQSGEVLGLSGPSGVGKSSLASVLAGMVKADAERLELPTILPNQANPVQWLIQQSEFA
FNPRLTLKASLNESWRGDGYLALLQEYGLEQSWLTRRPNQLSGGQLQRFNLIRALVPTTEYLICDEVTAHLDMVTQAQFW
QQLLASAKRRNLALLVISHDEYLLNAICHRVIEWPCTR
>Mature_198_residues
MLTLRNACLRRGEQKIAFPDLSLQSGEVLGLSGPSGVGKSSLASVLAGMVKADAERLELPTILPNQANPVQWLIQQSEFA
FNPRLTLKASLNESWRGDGYLALLQEYGLEQSWLTRRPNQLSGGQLQRFNLIRALVPTTEYLICDEVTAHLDMVTQAQFW
QQLLASAKRRNLALLVISHDEYLLNAICHRVIEWPCTR

Specific function: Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for energy coupling to the transport system. Important for S.aureus growth and survival during the infection process [H]

COG id: COG1124

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788506, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1789891, Length=191, Percent_Identity=36.6492146596859, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787500, Length=192, Percent_Identity=31.25, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693107, Length=199, Percent_Identity=31.6582914572864, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787758, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1789963, Length=208, Percent_Identity=30.2884615384615, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI1787370, Length=194, Percent_Identity=27.8350515463918, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786698, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI48994883, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1789890, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789962, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1786253, Length=177, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787547, Length=205, Percent_Identity=24.8780487804878, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=186, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788053, Length=197, Percent_Identity=27.9187817258883, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1786563, Length=172, Percent_Identity=31.9767441860465, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22212; Mature: 22212

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLRNACLRRGEQKIAFPDLSLQSGEVLGLSGPSGVGKSSLASVLAGMVKADAERLELP
CCCCHHHHHHCCCCEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TILPNQANPVQWLIQQSEFAFNPRLTLKASLNESWRGDGYLALLQEYGLEQSWLTRRPNQ
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCCC
LSGGQLQRFNLIRALVPTTEYLICDEVTAHLDMVTQAQFWQQLLASAKRRNLALLVISHD
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
EYLLNAICHRVIEWPCTR
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTLRNACLRRGEQKIAFPDLSLQSGEVLGLSGPSGVGKSSLASVLAGMVKADAERLELP
CCCCHHHHHHCCCCEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TILPNQANPVQWLIQQSEFAFNPRLTLKASLNESWRGDGYLALLQEYGLEQSWLTRRPNQ
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCHHHHHCCCCC
LSGGQLQRFNLIRALVPTTEYLICDEVTAHLDMVTQAQFWQQLLASAKRRNLALLVISHD
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
EYLLNAICHRVIEWPCTR
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA