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The map label for this gene is algB [H]

Identifier: 157963415

GI number: 157963415

Start: 4395511

End: 4396185

Strand: Reverse

Name: algB [H]

Synonym: Spea_3601

Alternate gene names: 157963415

Gene position: 4396185-4395511 (Counterclockwise)

Preceding gene: 157963416

Following gene: 157963414

Centisome position: 84.96

GC content: 44.3

Gene sequence:

>675_bases
ATGGTGACAGTTTTGCTAGCTGAGGATGATAGAGAGCTTAGCCAAAATATGGTTGAAATTCTTGAACTTGAGGGTTTTAG
TGTTACCGCGGTTGAAAGTGCAGAGGCTGCGATTAGAGCGAGTGAGAAGCAACATTTTGATATCGCACTGATGGACTTGC
TAATGGCGGGCATGACAGGGGTTGAAGCTATCTCGAACCTAAGACAAAACCAGCCATTAATTGCCGTCATTATTATCACG
GCTTATGCAACCGTCGATACCGCCGTCGATGCGATGAAAAAAGGTGCCGACAGTGTGATGACCAAGCCGTTTAAGAGTAG
CGAGCTTATCGTCACCATAAGGCGTAGCCTCGCGGAAAAACAGCTGTTCAAGAGTCGTATCGATCTCGATCCTGACCTTG
TCTACAGCGCACTGGCGAATCCTTATCGGCGTAAGGCGCTTACAGTGCTGGCAATCCATAAGGCTGTTAAGTTTATGGAC
TTATGCCGCCTAGTTGAAATAGAGGATCATACAAAGTTTAATTTTCATCTGCGTCAGTTAAAAAAGGCGGGGCTTGTGAT
GCAAAATGAGAACAAGCTCTACATTTTGACAAATACAGGCCAATTCGTGTTAACAAATCATAACATTTCGCAGGAGGGAA
TTTCCTTTTTAAACAGTGTTTTAGTTGGTAGTTGA

Upstream 100 bases:

>100_bases
GTGAGCAGATAGTCGCACTACATAATGGGAAGATGCATATTGTGAGCAGTAAACAGAAGGGCACTCGTGTGGAGCTAACC
TTTTATCGGGAGCAAGATTA

Downstream 100 bases:

>100_bases
TAACTAAAGTTCACAACTTTCCATGAGTGGTGAACTCTGGTTATCTATCTCTTTAGTAGTAACTCTTCAATACTTGAAAC
ATGTCCATAGAGGCATATCA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVTVLLAEDDRELSQNMVEILELEGFSVTAVESAEAAIRASEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSSELIVTIRRSLAEKQLFKSRIDLDPDLVYSALANPYRRKALTVLAIHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQFVLTNHNISQEGISFLNSVLVGS

Sequences:

>Translated_224_residues
MVTVLLAEDDRELSQNMVEILELEGFSVTAVESAEAAIRASEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSSELIVTIRRSLAEKQLFKSRIDLDPDLVYSALANPYRRKALTVLAIHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQFVLTNHNISQEGISFLNSVLVGS
>Mature_224_residues
MVTVLLAEDDRELSQNMVEILELEGFSVTAVESAEAAIRASEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSSELIVTIRRSLAEKQLFKSRIDLDPDLVYSALANPYRRKALTVLAIHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQFVLTNHNISQEGISFLNSVLVGS

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=32.4786324786325, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790552, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367329, Length=150, Percent_Identity=32.6666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=116, Percent_Identity=31.8965517241379, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=27.4336283185841, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24939; Mature: 24939

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVLLAEDDRELSQNMVEILELEGFSVTAVESAEAAIRASEKQHFDIALMDLLMAGMTG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
VEAISNLRQNQPLIAVIIITAYATVDTAVDAMKKGADSVMTKPFKSSELIVTIRRSLAEK
HHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHH
QLFKSRIDLDPDLVYSALANPYRRKALTVLAIHKAVKFMDLCRLVEIEDHTKFNFHLRQL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KKAGLVMQNENKLYILTNTGQFVLTNHNISQEGISFLNSVLVGS
HHCCCEEECCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTVLLAEDDRELSQNMVEILELEGFSVTAVESAEAAIRASEKQHFDIALMDLLMAGMTG
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCHH
VEAISNLRQNQPLIAVIIITAYATVDTAVDAMKKGADSVMTKPFKSSELIVTIRRSLAEK
HHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHH
QLFKSRIDLDPDLVYSALANPYRRKALTVLAIHKAVKFMDLCRLVEIEDHTKFNFHLRQL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KKAGLVMQNENKLYILTNTGQFVLTNHNISQEGISFLNSVLVGS
HHCCCEEECCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1899859; 1738315; 10984043; 9473053 [H]