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The map label for this gene is hutH [H]

Identifier: 157963389

GI number: 157963389

Start: 4364337

End: 4366013

Strand: Reverse

Name: hutH [H]

Synonym: Spea_3575

Alternate gene names: 157963389

Gene position: 4366013-4364337 (Counterclockwise)

Preceding gene: 157963390

Following gene: 157963388

Centisome position: 84.37

GC content: 44.48

Gene sequence:

>1677_bases
ATGATTGTTAAACATAAATTGAAACTAAGCTCTTTGGCTATTGCCTTAAGCTGTGCCGTTGTTCCTATGACTTCATTCAG
CGCTATGGCTGAAACAATTAGTCTAACAGGTAAAGATCTTACTATTGAGCAGTTGCTTAAAGTTCAAAGTGGTGAAGCCA
ATGTGACTGTCAGCAAAAAAGGCAAACAGAACATCCAAGACAGTTTCGATCTGTTAATGGATTCAGCTCGCCAAGGCACA
CCAGTTTATGGTCTAACGGTTGGCGTGGGTAAGAACAAGGATACAGAAGTTTTCGGTAAAGACGGTAAGATGTCAGATGA
AGCGGTAAAGCTGTCTGAAGACTTCAACCGTGACATGCTATTCACTCACGCTGCAGCGTCTGGCGAGCCGATCGCCCAAG
AAGTTGTGCGTATGGCTATGACTATCCGTCTAAACCAGATCGCGACTGGCCATGTAGGCGTACAACCTGACGTGGCTCGT
TTGTACGAGCAGTTTGTAAACAAGAACATTATTCCTGTTGTGCCATCAGATGGTTCGGTAGGCCTTTCTGACATTCTGCT
TGCTTCGCACATTGGTGCGGCAATGATGGGTGAGCATGAGGTGTTCTATAAAGGCGAGCGTATGCCAGCTGCTAAGGCAC
TAAAGGCTGCAGGTGTTAAGCCTCTGGTACCATTCGGTAAAGATGGTTTATCTATTCTTTCTAACAACGCGCTATCAACA
GCGCAGTTAGTCCATGCGATGGGGCAAGCAGAGCAGTTAATCGAATTCTCTCCAAAGCTGATTGCTGCGGGCCTTGAGTC
TATTAATGGCAACATCAGCCCAATTCTGCCTCATACGCTAGATGCCCGTCCTATGCCACACGTACAAGACGTAGGTAATG
ACATTCTTAAAAACCTGAAAGGCGGTTATCTGTTCCAACGTGATGAGAAGCGTCCTCTACAAGATAGCTTATCATTCCGT
GGCGCGCATTGGCCTGTAGCTAACGCTATTAGCCAGTACAACAATCTTGAAGAGTTGGTACACATTCAGATCAACAGCTC
TGACGATAATCCAACGGTATACTTGAATGCTAAGCACTCACGTTTCAACAAGTATCCACAAGTTGAGCAGTACTTCACAG
ATGGCAGGGTATCTGGCGCGATTAACTCGTCTGCTAACTTCGACACCATTCAGTTAGCAACGACAACTGAAGCCTTCAGC
ATTGCGATGGCTCAGCTAGGTAAGTATTCATCGAATCGTCAAATTAAGATGATTGACCCATACTTCACAGGCCTACCACG
TGCACTTGTGAACCCAGATGATACTAACGGTCAGAGTTTCTATACCCTACAGAATGGCTTTACAGCGCTGTTTGTTGATA
TCGCTCACGCGTCTAACCCAGTATCTTTCTATGGTCAGGCTAACCAAGGTGGTATCGAAGATAACTTCAGTAACTTCCAT
CAGGCTTCTAAGAACTTAACTACAGTTGTGGATGGCGTTTCTTACATCTACGCATTCGAGTTAATGACTTATGGTCAAGC
GCTAGACCTTCAGAAGAAAGTGCATGACCGTGACTTGTCTGATGCGAATAAGGCTTTATTAAAAGACTTACGTGAAACAG
TAAAGTTCTATGCCGATGATACTCGCACTTTTACTGTTGATATTGAAGCATCACAAAAATTCTTAATGAAATACTAA

Upstream 100 bases:

>100_bases
TAATCTTTGTTTAGGTTTTTAATAAAACATCTTGTCATTGTTCTAACTCAAATTTTATGTGGGCTAGTGTGGCATCACAC
AGTTATATAAAGGAATGGAA

Downstream 100 bases:

>100_bases
TAATCAATAAAGTATTTACGAAATAAATTAGTAGTTATTTGTGAAGTTAGAAGTACTAGATAATAAGTAGTTAAACTATT
AAGCCTTAATAAATGACATC

Product: phenylalanine/histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MIVKHKLKLSSLAIALSCAVVPMTSFSAMAETISLTGKDLTIEQLLKVQSGEANVTVSKKGKQNIQDSFDLLMDSARQGT
PVYGLTVGVGKNKDTEVFGKDGKMSDEAVKLSEDFNRDMLFTHAAASGEPIAQEVVRMAMTIRLNQIATGHVGVQPDVAR
LYEQFVNKNIIPVVPSDGSVGLSDILLASHIGAAMMGEHEVFYKGERMPAAKALKAAGVKPLVPFGKDGLSILSNNALST
AQLVHAMGQAEQLIEFSPKLIAAGLESINGNISPILPHTLDARPMPHVQDVGNDILKNLKGGYLFQRDEKRPLQDSLSFR
GAHWPVANAISQYNNLEELVHIQINSSDDNPTVYLNAKHSRFNKYPQVEQYFTDGRVSGAINSSANFDTIQLATTTEAFS
IAMAQLGKYSSNRQIKMIDPYFTGLPRALVNPDDTNGQSFYTLQNGFTALFVDIAHASNPVSFYGQANQGGIEDNFSNFH
QASKNLTTVVDGVSYIYAFELMTYGQALDLQKKVHDRDLSDANKALLKDLRETVKFYADDTRTFTVDIEASQKFLMKY

Sequences:

>Translated_558_residues
MIVKHKLKLSSLAIALSCAVVPMTSFSAMAETISLTGKDLTIEQLLKVQSGEANVTVSKKGKQNIQDSFDLLMDSARQGT
PVYGLTVGVGKNKDTEVFGKDGKMSDEAVKLSEDFNRDMLFTHAAASGEPIAQEVVRMAMTIRLNQIATGHVGVQPDVAR
LYEQFVNKNIIPVVPSDGSVGLSDILLASHIGAAMMGEHEVFYKGERMPAAKALKAAGVKPLVPFGKDGLSILSNNALST
AQLVHAMGQAEQLIEFSPKLIAAGLESINGNISPILPHTLDARPMPHVQDVGNDILKNLKGGYLFQRDEKRPLQDSLSFR
GAHWPVANAISQYNNLEELVHIQINSSDDNPTVYLNAKHSRFNKYPQVEQYFTDGRVSGAINSSANFDTIQLATTTEAFS
IAMAQLGKYSSNRQIKMIDPYFTGLPRALVNPDDTNGQSFYTLQNGFTALFVDIAHASNPVSFYGQANQGGIEDNFSNFH
QASKNLTTVVDGVSYIYAFELMTYGQALDLQKKVHDRDLSDANKALLKDLRETVKFYADDTRTFTVDIEASQKFLMKY
>Mature_558_residues
MIVKHKLKLSSLAIALSCAVVPMTSFSAMAETISLTGKDLTIEQLLKVQSGEANVTVSKKGKQNIQDSFDLLMDSARQGT
PVYGLTVGVGKNKDTEVFGKDGKMSDEAVKLSEDFNRDMLFTHAAASGEPIAQEVVRMAMTIRLNQIATGHVGVQPDVAR
LYEQFVNKNIIPVVPSDGSVGLSDILLASHIGAAMMGEHEVFYKGERMPAAKALKAAGVKPLVPFGKDGLSILSNNALST
AQLVHAMGQAEQLIEFSPKLIAAGLESINGNISPILPHTLDARPMPHVQDVGNDILKNLKGGYLFQRDEKRPLQDSLSFR
GAHWPVANAISQYNNLEELVHIQINSSDDNPTVYLNAKHSRFNKYPQVEQYFTDGRVSGAINSSANFDTIQLATTTEAFS
IAMAQLGKYSSNRQIKMIDPYFTGLPRALVNPDDTNGQSFYTLQNGFTALFVDIAHASNPVSFYGQANQGGIEDNFSNFH
QASKNLTTVVDGVSYIYAFELMTYGQALDLQKKVHDRDLSDANKALLKDLRETVKFYADDTRTFTVDIEASQKFLMKY

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=549, Percent_Identity=22.2222222222222, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567831, Length=500, Percent_Identity=23.4, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 61073; Mature: 61073

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKHKLKLSSLAIALSCAVVPMTSFSAMAETISLTGKDLTIEQLLKVQSGEANVTVSKK
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECC
GKQNIQDSFDLLMDSARQGTPVYGLTVGVGKNKDTEVFGKDGKMSDEAVKLSEDFNRDML
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHCCCCEE
FTHAAASGEPIAQEVVRMAMTIRLNQIATGHVGVQPDVARLYEQFVNKNIIPVVPSDGSV
EEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
GLSDILLASHIGAAMMGEHEVFYKGERMPAAKALKAAGVKPLVPFGKDGLSILSNNALST
CHHHHHHHHHHCHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHH
AQLVHAMGQAEQLIEFSPKLIAAGLESINGNISPILPHTLDARPMPHVQDVGNDILKNLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GGYLFQRDEKRPLQDSLSFRGAHWPVANAISQYNNLEELVHIQINSSDDNPTVYLNAKHS
CCEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHCCHHHEEEEEEECCCCCCEEEEECCHH
RFNKYPQVEQYFTDGRVSGAINSSANFDTIQLATTTEAFSIAMAQLGKYSSNRQIKMIDP
HCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEECH
YFTGLPRALVNPDDTNGQSFYTLQNGFTALFVDIAHASNPVSFYGQANQGGIEDNFSNFH
HHHCCCHHHCCCCCCCCCEEEEECCCCEEEEEEEHHCCCCEEEEECCCCCCCCCCHHHHH
QASKNLTTVVDGVSYIYAFELMTYGQALDLQKKVHDRDLSDANKALLKDLRETVKFYADD
HHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
TRTFTVDIEASQKFLMKY
CEEEEEEECCCCHHHHCC
>Mature Secondary Structure
MIVKHKLKLSSLAIALSCAVVPMTSFSAMAETISLTGKDLTIEQLLKVQSGEANVTVSKK
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEECC
GKQNIQDSFDLLMDSARQGTPVYGLTVGVGKNKDTEVFGKDGKMSDEAVKLSEDFNRDML
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHCCCCEE
FTHAAASGEPIAQEVVRMAMTIRLNQIATGHVGVQPDVARLYEQFVNKNIIPVVPSDGSV
EEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
GLSDILLASHIGAAMMGEHEVFYKGERMPAAKALKAAGVKPLVPFGKDGLSILSNNALST
CHHHHHHHHHHCHHHCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHH
AQLVHAMGQAEQLIEFSPKLIAAGLESINGNISPILPHTLDARPMPHVQDVGNDILKNLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GGYLFQRDEKRPLQDSLSFRGAHWPVANAISQYNNLEELVHIQINSSDDNPTVYLNAKHS
CCEEEECCCCCCHHHHHCCCCCCCHHHHHHHHHCCHHHEEEEEEECCCCCCEEEEECCHH
RFNKYPQVEQYFTDGRVSGAINSSANFDTIQLATTTEAFSIAMAQLGKYSSNRQIKMIDP
HCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEECH
YFTGLPRALVNPDDTNGQSFYTLQNGFTALFVDIAHASNPVSFYGQANQGGIEDNFSNFH
HHHCCCHHHCCCCCCCCCEEEEECCCCEEEEEEEHHCCCCEEEEECCCCCCCCCCHHHHH
QASKNLTTVVDGVSYIYAFELMTYGQALDLQKKVHDRDLSDANKALLKDLRETVKFYADD
HHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
TRTFTVDIEASQKFLMKY
CEEEEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA