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The map label for this gene is ifcA [H]

Identifier: 157963388

GI number: 157963388

Start: 4362382

End: 4364142

Strand: Reverse

Name: ifcA [H]

Synonym: Spea_3574

Alternate gene names: 157963388

Gene position: 4364142-4362382 (Counterclockwise)

Preceding gene: 157963389

Following gene: 157963386

Centisome position: 84.34

GC content: 45.26

Gene sequence:

>1761_bases
ATGAATTTCAAATTAAAAAAGTCAGCGCTAGGCGTGGCAATTGCCTTACCTGTAATATTAGTTGGTTGTGCAGTAACAAG
CGAAATGATCAAATCACAAGGTACGGCTAAAGGTCGACATGGTGATATTACTGTAGAAACAACGTTCCAGAATGGTCAAA
TTACTGCAATTGATATCGTAAAACAAAAAGAGAATAAAGTTCTATCCGCAGCCGTTTATAAAGACGTAAAGCAAGCAATC
ATTGATAACAACAGTGTCAACGTGGATGGCATCTCTGGTGCAACGGCCACTTCTGATGGCTTCAAGCAGGCGGTTGCTAA
GTCGGCTGAGCTTGCAGGGGTGACACTGCTCGCAACAGCAGCAATCAATGGTAAAAAAGTTGATGCACAGCCATCAGAAT
ACACCTATGACGTTGTTGTTATTGGTGCCGGTGGTGCCGGTTTCTCTGCAGGTATCGAAGCGGTTGAGGCTGGCGTATCT
GCTGTTATCATCGAAAAGCAGCCTATTATTGGTGGTAACTCACTTATCTCTGGCGGCGAAATGAACGTGGCGGGTAGCTG
GGTTCAAAAAGGAATGGGCATCACCGATAGCAAAGAGTCGTTTATTGAAGATACGTTAAAGGGCGGCGACTATAAAGGTG
ATCCAGAGATGGTGCGGGTAATGGTTGATAATGCTGTTGAAGCGGCCGAATGGTTACGTGACGATATCAAAGTTGATTTC
TACAAAGACCAAATCTTCCAGTTTGGTGGCCACTCAGTAAAACGTGCCGTCATCCCTAAAGGACACACTGGCGCAGAAGT
ATTAAGCAAGTTTGCTGTTAAGGCTGAAGAGATTGGTTTACCTGTTCATATGAACACAACGGCAAAGAACCTTATCCAAG
ATGAGACAGGCCGCGTTGTAGGCGTTAAGGCGATGAAGAACGGTAAGGTTATCACTTATCACGCTAAGAAAGCGGTGGTA
ATGGCTGCTGGTGGCTTTGGCGCAAATATCGAAATGCGTAAGAAATTCAACCCTGAATACGATGAGCGCTACGGTACAAC
TAACCACTCAGGTGCAACCGGTGACGGTATCTTAATGTCTGAAGCGGTTAACGCTAAGACTGCCAACCTAGGCGAAATCC
AAGCGTACCCAATCTGTAACCCTGAAACAGGTGCTATCGCGTTAATCGCCGATGCGCGTTTCTTTGGTGCTATCTTGGTT
AACCAAGAGGGTAAGCGCTTTGTAGAAGAACTTGATCGCCGTGACGTTATCTCTAACGCAATCTTGAACCAAACGGGCAA
ATACACTTATGTTATTTGGAACCAAAAAATCGATGATCTTGCTAAGACTATCGACATGCACCCTGGCGAATTCAACGATC
TACACTCACGTGGTTTAATGTTTGAAGTTGACAGCATCGAAGAAGCGGCTGCGAAATTCAATATTCCTTTAGCTGCGCTA
CAAAGCACTATCAGTGATGTTAATAAGTATGCGGCTACAGGCAAGGATTTAGCATTTAATAACCGTGCAGGTCTTGTTGA
CATGTCTGAAGGCAAGTACTGGATCTTAAAAGCAACGCCATCAGTCCATCACACAATGGGCGGTGTTGCTACAACGACTA
AAGCAGAAGTATTAGACAATAGTGGCACCATCATCAAAGGCTTATACGCTGCTGGTGAAGTAACCGGTCTAACTCATGGC
TCTAACCGTCTTGGCGGTAACGCCTATACCGATATCATCGTTTTTGGTCGCATTGCTGGTCAGCAAGCCGCGGCACAATA
A

Upstream 100 bases:

>100_bases
GACATCAAACTTTTAGTTTGATGTCATTTACCTATGAAAAAATTAGTGAAACCGTAATTAATTGTTCTATTGAACACTCA
TTACTTTTAAAGAGACCCCT

Downstream 100 bases:

>100_bases
TTACAGTTTTAAAAGTTAAAAGTTAAAAGTAAAAAGTAAAAAGTAAAAAGTAAAAAGTAAAAAGTAAAAAGTAAAAAGTA
AAAAGTAAGCCGACCACCCA

Product: flavocytochrome c

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MNFKLKKSALGVAIALPVILVGCAVTSEMIKSQGTAKGRHGDITVETTFQNGQITAIDIVKQKENKVLSAAVYKDVKQAI
IDNNSVNVDGISGATATSDGFKQAVAKSAELAGVTLLATAAINGKKVDAQPSEYTYDVVVIGAGGAGFSAGIEAVEAGVS
AVIIEKQPIIGGNSLISGGEMNVAGSWVQKGMGITDSKESFIEDTLKGGDYKGDPEMVRVMVDNAVEAAEWLRDDIKVDF
YKDQIFQFGGHSVKRAVIPKGHTGAEVLSKFAVKAEEIGLPVHMNTTAKNLIQDETGRVVGVKAMKNGKVITYHAKKAVV
MAAGGFGANIEMRKKFNPEYDERYGTTNHSGATGDGILMSEAVNAKTANLGEIQAYPICNPETGAIALIADARFFGAILV
NQEGKRFVEELDRRDVISNAILNQTGKYTYVIWNQKIDDLAKTIDMHPGEFNDLHSRGLMFEVDSIEEAAAKFNIPLAAL
QSTISDVNKYAATGKDLAFNNRAGLVDMSEGKYWILKATPSVHHTMGGVATTTKAEVLDNSGTIIKGLYAAGEVTGLTHG
SNRLGGNAYTDIIVFGRIAGQQAAAQ

Sequences:

>Translated_586_residues
MNFKLKKSALGVAIALPVILVGCAVTSEMIKSQGTAKGRHGDITVETTFQNGQITAIDIVKQKENKVLSAAVYKDVKQAI
IDNNSVNVDGISGATATSDGFKQAVAKSAELAGVTLLATAAINGKKVDAQPSEYTYDVVVIGAGGAGFSAGIEAVEAGVS
AVIIEKQPIIGGNSLISGGEMNVAGSWVQKGMGITDSKESFIEDTLKGGDYKGDPEMVRVMVDNAVEAAEWLRDDIKVDF
YKDQIFQFGGHSVKRAVIPKGHTGAEVLSKFAVKAEEIGLPVHMNTTAKNLIQDETGRVVGVKAMKNGKVITYHAKKAVV
MAAGGFGANIEMRKKFNPEYDERYGTTNHSGATGDGILMSEAVNAKTANLGEIQAYPICNPETGAIALIADARFFGAILV
NQEGKRFVEELDRRDVISNAILNQTGKYTYVIWNQKIDDLAKTIDMHPGEFNDLHSRGLMFEVDSIEEAAAKFNIPLAAL
QSTISDVNKYAATGKDLAFNNRAGLVDMSEGKYWILKATPSVHHTMGGVATTTKAEVLDNSGTIIKGLYAAGEVTGLTHG
SNRLGGNAYTDIIVFGRIAGQQAAAQ
>Mature_586_residues
MNFKLKKSALGVAIALPVILVGCAVTSEMIKSQGTAKGRHGDITVETTFQNGQITAIDIVKQKENKVLSAAVYKDVKQAI
IDNNSVNVDGISGATATSDGFKQAVAKSAELAGVTLLATAAINGKKVDAQPSEYTYDVVVIGAGGAGFSAGIEAVEAGVS
AVIIEKQPIIGGNSLISGGEMNVAGSWVQKGMGITDSKESFIEDTLKGGDYKGDPEMVRVMVDNAVEAAEWLRDDIKVDF
YKDQIFQFGGHSVKRAVIPKGHTGAEVLSKFAVKAEEIGLPVHMNTTAKNLIQDETGRVVGVKAMKNGKVITYHAKKAVV
MAAGGFGANIEMRKKFNPEYDERYGTTNHSGATGDGILMSEAVNAKTANLGEIQAYPICNPETGAIALIADARFFGAILV
NQEGKRFVEELDRRDVISNAILNQTGKYTYVIWNQKIDDLAKTIDMHPGEFNDLHSRGLMFEVDSIEEAAAKFNIPLAAL
QSTISDVNKYAATGKDLAFNNRAGLVDMSEGKYWILKATPSVHHTMGGVATTTKAEVLDNSGTIIKGLYAAGEVTGLTHG
SNRLGGNAYTDIIVFGRIAGQQAAAQ

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=517, Percent_Identity=27.4661508704062, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788928, Length=471, Percent_Identity=26.5392781316348, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786942, Length=471, Percent_Identity=25.9023354564756, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790597, Length=424, Percent_Identity=25.7075471698113, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71986328, Length=470, Percent_Identity=30.6382978723404, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17505833, Length=409, Percent_Identity=26.8948655256724, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17550100, Length=513, Percent_Identity=27.4853801169591, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320788, Length=477, Percent_Identity=32.4947589098532, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6322511, Length=475, Percent_Identity=29.8947368421053, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322416, Length=474, Percent_Identity=28.2700421940928, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322701, Length=481, Percent_Identity=28.0665280665281, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137288, Length=495, Percent_Identity=27.4747474747475, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655642, Length=495, Percent_Identity=27.4747474747475, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655647, Length=495, Percent_Identity=27.4747474747475, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 62156; Mature: 62156

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKLKKSALGVAIALPVILVGCAVTSEMIKSQGTAKGRHGDITVETTFQNGQITAIDIV
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEE
KQKENKVLSAAVYKDVKQAIIDNNSVNVDGISGATATSDGFKQAVAKSAELAGVTLLATA
ECCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEE
AINGKKVDAQPSEYTYDVVVIGAGGAGFSAGIEAVEAGVSAVIIEKQPIIGGNSLISGGE
ECCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEECCCC
MNVAGSWVQKGMGITDSKESFIEDTLKGGDYKGDPEMVRVMVDNAVEAAEWLRDDIKVDF
CCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHEEEEHHHHHHHHHHHHHCCEEEE
YKDQIFQFGGHSVKRAVIPKGHTGAEVLSKFAVKAEEIGLPVHMNTTAKNLIQDETGRVV
EHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHCCCCEE
GVKAMKNGKVITYHAKKAVVMAAGGFGANIEMRKKFNPEYDERYGTTNHSGATGDGILMS
EEEEECCCCEEEEECCEEEEEEECCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCCEEEE
EAVNAKTANLGEIQAYPICNPETGAIALIADARFFGAILVNQEGKRFVEELDRRDVISNA
CCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
ILNQTGKYTYVIWNQKIDDLAKTIDMHPGEFNDLHSRGLMFEVDSIEEAAAKFNIPLAAL
HHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCCEEEECCHHHHHHHCCCCHHHH
QSTISDVNKYAATGKDLAFNNRAGLVDMSEGKYWILKATPSVHHTMGGVATTTKAEVLDN
HHHHHHHHHHHCCCCCEEECCCCCEEEECCCCEEEEECCCCHHHHCCCCEECCHHHHCCC
SGTIIKGLYAAGEVTGLTHGSNRLGGNAYTDIIVFGRIAGQQAAAQ
CCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCCHHCCC
>Mature Secondary Structure
MNFKLKKSALGVAIALPVILVGCAVTSEMIKSQGTAKGRHGDITVETTFQNGQITAIDIV
CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEE
KQKENKVLSAAVYKDVKQAIIDNNSVNVDGISGATATSDGFKQAVAKSAELAGVTLLATA
ECCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEE
AINGKKVDAQPSEYTYDVVVIGAGGAGFSAGIEAVEAGVSAVIIEKQPIIGGNSLISGGE
ECCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCEECCCC
MNVAGSWVQKGMGITDSKESFIEDTLKGGDYKGDPEMVRVMVDNAVEAAEWLRDDIKVDF
CCCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHEEEEHHHHHHHHHHHHHCCEEEE
YKDQIFQFGGHSVKRAVIPKGHTGAEVLSKFAVKAEEIGLPVHMNTTAKNLIQDETGRVV
EHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHCCCCEE
GVKAMKNGKVITYHAKKAVVMAAGGFGANIEMRKKFNPEYDERYGTTNHSGATGDGILMS
EEEEECCCCEEEEECCEEEEEEECCCCCCEEECCCCCCCHHHHCCCCCCCCCCCCCEEEE
EAVNAKTANLGEIQAYPICNPETGAIALIADARFFGAILVNQEGKRFVEELDRRDVISNA
CCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHH
ILNQTGKYTYVIWNQKIDDLAKTIDMHPGEFNDLHSRGLMFEVDSIEEAAAKFNIPLAAL
HHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHCCCEEEECCHHHHHHHCCCCHHHH
QSTISDVNKYAATGKDLAFNNRAGLVDMSEGKYWILKATPSVHHTMGGVATTTKAEVLDN
HHHHHHHHHHHCCCCCEEECCCCCEEEECCCCEEEEECCCCHHHHCCCCEECCHHHHCCC
SGTIIKGLYAAGEVTGLTHGSNRLGGNAYTDIIVFGRIAGQQAAAQ
CCCEEEEEECCCCEEEECCCCCCCCCCCEEEEEEEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]