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The map label for this gene is hflC [H]

Identifier: 157963351

GI number: 157963351

Start: 4320239

End: 4321117

Strand: Reverse

Name: hflC [H]

Synonym: Spea_3537

Alternate gene names: 157963351

Gene position: 4321117-4320239 (Counterclockwise)

Preceding gene: 157963352

Following gene: 157963350

Centisome position: 83.51

GC content: 43.8

Gene sequence:

>879_bases
ATGGGTAGATTTACAGCGATAATCGTAGCGGTGCTTATTGCGATTTCATTGTCTTCACTTTTGGTTGTGAACGAAGGCGA
ACGTGCCATTGTTTCACGCTTCGGTAAAGTTCTTAAAGACGACGGTGTGACGCGTGTTTATGCTCCAGGTCTTCACTTGA
AAATACCTATGCTTGATAAAATCAAGTATATGGATTCGCGAGTACAAACTCTAGATGGCGCAGCGGACCGCTTCGTAACT
TCTGAGAAGAAAGACTTAATGGTCGACTCATACGTGAAGTGGCGCATTAAAGATTTCGAACGTTATTACCTTTCTACCAA
TGGTGGTATTAAGGCTAATGCCGAAACTTTGCTACAGCGTAAGATTAACAACGATCTTCGTACCGAGTTTGGTCGCAGAA
CGATTAAAGAGATTGTTTCTGGTAGCCGCGATGAGTTGCAATCGGATGCATTGAAAAATGCAGCCGAGAGTGCGAAAGAC
TTAGGTGTTGAAGTTGTCGATGTTCGAGTTAAGCAAATTAACTTACCTGCAAACGTCAGTACCAGTATTTATCAGCGTAT
GCGCGCAGAGCGTCAAGCCGTTGCTAAAGAACATCGTGCACAGGGTCAGGAGCAAGCGGAAATTATCCGTGCTAAGACTG
ATGCTAGTGTAACCATTCAAACTGCGGAAGCTGAGCGTAAAGCTCTGACTATTCGTGGTGAAGGTGATGCAGAGGCGGCT
AAGATCTATGCCGACGCTTACACCAAAGATGAAGAGTTCTTCAGCTTTACGCGTAGTTTAGACGCATATAAGGCAAGCTT
CTCTGGTGATAAAGATGTAATGGTGCTTGAACCAGACAGTGAGTTCTTTAGATATATGAAGAGTTCTACTGGAAAATAA

Upstream 100 bases:

>100_bases
GCCTGCGATGTCAGTTAATAGTACAACTCACACTAACAGCAGCATTCCTCTCGATGGTCGCCCATCTAGAGGTGAACGTT
CGTTGGGGAGGAACTAAGTG

Downstream 100 bases:

>100_bases
TCTTTTTGATTAATAAAAAGGTCTAACGATAAGTTAGGCCTTTTTTTATGCCTGATATACGCAATTTATGACCGGTCGTT
AATTCCTACCTATTCAGTCA

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVT
SEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKD
LGVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
KIYADAYTKDEEFFSFTRSLDAYKASFSGDKDVMVLEPDSEFFRYMKSSTGK

Sequences:

>Translated_292_residues
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVT
SEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKD
LGVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
KIYADAYTKDEEFFSFTRSLDAYKASFSGDKDVMVLEPDSEFFRYMKSSTGK
>Mature_291_residues
GRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDKIKYMDSRVQTLDGAADRFVTS
EKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQRKINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDL
GVEVVDVRVKQINLPANVSTSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAAK
IYADAYTKDEEFFSFTRSLDAYKASFSGDKDVMVLEPDSEFFRYMKSSTGK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=312, Percent_Identity=52.8846153846154, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1786697, Length=294, Percent_Identity=24.8299319727891, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 32728; Mature: 32596

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDK
CCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHH
IKYMDSRVQTLDGAADRFVTSEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQR
HHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHH
KINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDLGVEVVDVRVKQINLPANVS
HHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
TSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
KIYADAYTKDEEFFSFTRSLDAYKASFSGDKDVMVLEPDSEFFRYMKSSTGK
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHCCCC
>Mature Secondary Structure 
GRFTAIIVAVLIAISLSSLLVVNEGERAIVSRFGKVLKDDGVTRVYAPGLHLKIPMLDK
CHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCEEECCHHHH
IKYMDSRVQTLDGAADRFVTSEKKDLMVDSYVKWRIKDFERYYLSTNGGIKANAETLLQR
HHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHH
KINNDLRTEFGRRTIKEIVSGSRDELQSDALKNAAESAKDLGVEVVDVRVKQINLPANVS
HHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCC
TSIYQRMRAERQAVAKEHRAQGQEQAEIIRAKTDASVTIQTAEAERKALTIRGEGDAEAA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
KIYADAYTKDEEFFSFTRSLDAYKASFSGDKDVMVLEPDSEFFRYMKSSTGK
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]