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The map label for this gene is hflK [H]

Identifier: 157963352

GI number: 157963352

Start: 4321121

End: 4322272

Strand: Reverse

Name: hflK [H]

Synonym: Spea_3538

Alternate gene names: 157963352

Gene position: 4322272-4321121 (Counterclockwise)

Preceding gene: 157963353

Following gene: 157963351

Centisome position: 83.53

GC content: 45.31

Gene sequence:

>1152_bases
ATGGCTTGGAACGAGCCCGGTAACAAGGGTCAAGACCCTTGGGGAAATGGCAATAAAGGTGGTAATGATAAAGGACCACC
AGATTTAGATGAAGTTTTTCGTAACCTTTCTAAGCGCTTCGGTGGCAAGGGTAATGGTTCTGGAGGCAGCATTAGTGCGG
CCAGCTTAATCATTGTTCTAGTTATCGCAATAGTTGTATGGGGACTTTCAGGTTTCTATACGGTTAAAGAAGCTGAGAAA
GGTGTTGCTCTTCGTTTTGGCGAATATATCGGGGAAGTCGATCCAGGCCTTCAATGGAAAGCCACTTTTATTGATGAAGT
GACGCCTGTAAACGTACAAACGGTTCGTTCTATTCCAGCTTCTGGAAGTATGCTAACAGCCGACGAAAACGTTGTCCTTG
TTCAACTAGATGTGCAGTATCGAGTGAGTAACGCGAAAGATTACCTCTATAGCGTAGTCGATGCAGATGCGAGTTTGCGT
GAGGCGACAGATAGCGCGCTACGTTACGTTATCGGCCATAACACTATGGATGATATCTTGACTACTGGTCGTGATAAAAT
TCGTCGTGACACATGGGACGAAATCGAGCGAATTATCAAACCGTATAAACTCGGTATTTCAGTTGTTGATGTGAACTTCT
TGCCAGCTCGTCCACCAGAAGAGGTGAAAGATGCCTTCGATGATGCGATTGCAGCACAAGAGGATGAGCAACGTTTCATT
CGTGAAGCTGAAGCTTACTCACGTCAGTTAGAGCCAAAGGTTCGTGGTACTGTACAGCGCATGGATCAACAAGCGATTGC
TTATAAGCAGCGAGTGATTTTAGAAGCGAAAGGTAAAGTAGCTCGTTTCGAACAGTTACTGCCTGAGTATCAAGCGGCGC
CAGAAGTGACTCGCGAACGTATGTACTTTGATACGATGCAGGAAGTTATGAGTGGCACCAATAAAGTTCTTATCGATGCC
AAGAATAGTGGTAACTTGATGTATTTACCATTAGACAAGTTGATGCAGAATAGCCAGTCGCATAAGTCTGCCAGCACTAA
TACTAAACCGGCAAAGCCTGCGATGTCAGTTAATAGTACAACTCACACTAACAGCAGCATTCCTCTCGATGGTCGCCCAT
CTAGAGGTGAACGTTCGTTGGGGAGGAACTAA

Upstream 100 bases:

>100_bases
CAGAGCCAAGGTGAATTAGAGACTTTTGTGGTCGACCCAGTCGTCGCATAATTAAGTATTTTAGTAATCTCGTTTATTTC
ATACACTTATGGAGTACTAA

Downstream 100 bases:

>100_bases
GTGATGGGTAGATTTACAGCGATAATCGTAGCGGTGCTTATTGCGATTTCATTGTCTTCACTTTTGGTTGTGAACGAAGG
CGAACGTGCCATTGTTTCAC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MAWNEPGNKGQDPWGNGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSISAASLIIVLVIAIVVWGLSGFYTVKEAEK
GVALRFGEYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVSNAKDYLYSVVDADASLR
EATDSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGISVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFI
REAEAYSRQLEPKVRGTVQRMDQQAIAYKQRVILEAKGKVARFEQLLPEYQAAPEVTRERMYFDTMQEVMSGTNKVLIDA
KNSGNLMYLPLDKLMQNSQSHKSASTNTKPAKPAMSVNSTTHTNSSIPLDGRPSRGERSLGRN

Sequences:

>Translated_383_residues
MAWNEPGNKGQDPWGNGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSISAASLIIVLVIAIVVWGLSGFYTVKEAEK
GVALRFGEYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVSNAKDYLYSVVDADASLR
EATDSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGISVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFI
REAEAYSRQLEPKVRGTVQRMDQQAIAYKQRVILEAKGKVARFEQLLPEYQAAPEVTRERMYFDTMQEVMSGTNKVLIDA
KNSGNLMYLPLDKLMQNSQSHKSASTNTKPAKPAMSVNSTTHTNSSIPLDGRPSRGERSLGRN
>Mature_382_residues
AWNEPGNKGQDPWGNGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSISAASLIIVLVIAIVVWGLSGFYTVKEAEKG
VALRFGEYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPASGSMLTADENVVLVQLDVQYRVSNAKDYLYSVVDADASLRE
ATDSALRYVIGHNTMDDILTTGRDKIRRDTWDEIERIIKPYKLGISVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFIR
EAEAYSRQLEPKVRGTVQRMDQQAIAYKQRVILEAKGKVARFEQLLPEYQAAPEVTRERMYFDTMQEVMSGTNKVLIDAK
NSGNLMYLPLDKLMQNSQSHKSASTNTKPAKPAMSVNSTTHTNSSIPLDGRPSRGERSLGRN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=372, Percent_Identity=54.8387096774194, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42387; Mature: 42256

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGNKGQDPWGNGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSISAASLIIVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
VIAIVVWGLSGFYTVKEAEKGVALRFGEYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPA
HHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCHHHHHCCCC
SGSMLTADENVVLVQLDVQYRVSNAKDYLYSVVDADASLREATDSALRYVIGHNTMDDIL
CCCEEECCCCEEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
TTGRDKIRRDTWDEIERIIKPYKLGISVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFI
HCCHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHH
REAEAYSRQLEPKVRGTVQRMDQQAIAYKQRVILEAKGKVARFEQLLPEYQAAPEVTRER
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
MYFDTMQEVMSGTNKVLIDAKNSGNLMYLPLDKLMQNSQSHKSASTNTKPAKPAMSVNST
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCCCHHHCCCCCCCCCCCCCCCCCCC
THTNSSIPLDGRPSRGERSLGRN
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWNEPGNKGQDPWGNGNKGGNDKGPPDLDEVFRNLSKRFGGKGNGSGGSISAASLIIVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
VIAIVVWGLSGFYTVKEAEKGVALRFGEYIGEVDPGLQWKATFIDEVTPVNVQTVRSIPA
HHHHHHHCCCCCEEHHHHHCCHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCHHHHHCCCC
SGSMLTADENVVLVQLDVQYRVSNAKDYLYSVVDADASLREATDSALRYVIGHNTMDDIL
CCCEEECCCCEEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
TTGRDKIRRDTWDEIERIIKPYKLGISVVDVNFLPARPPEEVKDAFDDAIAAQEDEQRFI
HCCHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHH
REAEAYSRQLEPKVRGTVQRMDQQAIAYKQRVILEAKGKVARFEQLLPEYQAAPEVTRER
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
MYFDTMQEVMSGTNKVLIDAKNSGNLMYLPLDKLMQNSQSHKSASTNTKPAKPAMSVNST
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHCCCHHHCCCCCCCCCCCCCCCCCCC
THTNSSIPLDGRPSRGERSLGRN
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]