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The map label for this gene is fecD [C]

Identifier: 157963343

GI number: 157963343

Start: 4311646

End: 4312692

Strand: Reverse

Name: fecD [C]

Synonym: Spea_3529

Alternate gene names: 157963343

Gene position: 4312692-4311646 (Counterclockwise)

Preceding gene: 157963344

Following gene: 157963342

Centisome position: 83.34

GC content: 49.28

Gene sequence:

>1047_bases
ATGTTTGTAGCAAAAACACGCGCGATACAACCTGTGCAATGGCTCGGGATTGCCATTGTGGTTGGCTTAGTTGGTATTTG
TGCTGGGCGCTTCTCGATTAACCCAAGCGATTTATTCAGCGCTATTCAAAAACTGCCATCGGTGCTGAGTAGTTTAATAC
TTACAGGCCAAGTACCTGATAACTTGACTCAGGAAGAGCGGGTCATTCTGTTGATCCGTTTTCCTCGCTTACTGACAGCA
CTGATTGTTGGCGCCGGGCTGGCCGTATCTGGCGCGGTTTATCAGGGAGTCTTTCGTAATCCGCTGGTTTCTCCCGACAT
TTTAGGTGTGGCATCTGGCTGTATGTTTGGCGCGGCTATGGGGCTGATTTTACCGGGTAGCAGTTGGCTTATGGTGCAAT
TGCTGGCATTTATTTGTGGTTTAACTGCAGCATGTGCTGCCATGTTTATGGCTAAGCGCTTTGGTAGTAACAGCTTACTG
CTGATGATTATGACCGGCATTATTGTCGGCTCGATATTTGGCGCAGGCCTTACCATGTTAAAAGCGCTAGCTGATCCTTA
TGGTGAGCTACCAGCTATTGTTTTTTGGTTGATGGGATCTTTGTCGGTGAGCAGCTGGAGTACTGTGGCGCAGCTGATTG
TGCCTGTAGCTCTAGGTTATGGTCTTATCCATACGCTGCGTTATCGCCTCAATGTACTTTGCTTGGGCGATCACCAATGC
CGCAGCCTTGGGGTGGAACCTGCAAGACTGCGTATGGTGTTAATTGTGACTAGCTCGTTTATCGTCGCTTCTTGTGTCGC
AACCGTTGGCTCAGTTGCTTGGATTGGTCTCGTTGTACCGCACATGGTGCGCACTTTTACTGGTGCTAACAATATGCGGC
TTATTCCCTTATCAACTGCGGTAGGTGCGATATTTTTGCTGTTCGCAGACAGTGTGGCACGGGCGAGCTTTAGCATGGAG
ATCCCAATCGGTATCGTGACCTCATTGGTTGGTGCACCACTGTTTGCCTTTTTGCTGTTTCGTTTCCGTCAGGGAGGGGC
CTACTAA

Upstream 100 bases:

>100_bases
CTGAAAGATTTATAAACATCGATCTAAATGCCGAAATTGCCCATTACTATCAAGTGGCCTTTGGTGACGCTTGCCTTTCA
CCGCTACAAGAGATGAGCCA

Downstream 100 bases:

>100_bases
TGCTATCGGTTAACCATATTAGTTACGCTGTCGGTGACAAGTGCTTATTAGAAGATATTAGTTTCGAGTTAGCAGCAGGC
GAGTTTTTAGCGGTTTTAGG

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MFVAKTRAIQPVQWLGIAIVVGLVGICAGRFSINPSDLFSAIQKLPSVLSSLILTGQVPDNLTQEERVILLIRFPRLLTA
LIVGAGLAVSGAVYQGVFRNPLVSPDILGVASGCMFGAAMGLILPGSSWLMVQLLAFICGLTAACAAMFMAKRFGSNSLL
LMIMTGIIVGSIFGAGLTMLKALADPYGELPAIVFWLMGSLSVSSWSTVAQLIVPVALGYGLIHTLRYRLNVLCLGDHQC
RSLGVEPARLRMVLIVTSSFIVASCVATVGSVAWIGLVVPHMVRTFTGANNMRLIPLSTAVGAIFLLFADSVARASFSME
IPIGIVTSLVGAPLFAFLLFRFRQGGAY

Sequences:

>Translated_348_residues
MFVAKTRAIQPVQWLGIAIVVGLVGICAGRFSINPSDLFSAIQKLPSVLSSLILTGQVPDNLTQEERVILLIRFPRLLTA
LIVGAGLAVSGAVYQGVFRNPLVSPDILGVASGCMFGAAMGLILPGSSWLMVQLLAFICGLTAACAAMFMAKRFGSNSLL
LMIMTGIIVGSIFGAGLTMLKALADPYGELPAIVFWLMGSLSVSSWSTVAQLIVPVALGYGLIHTLRYRLNVLCLGDHQC
RSLGVEPARLRMVLIVTSSFIVASCVATVGSVAWIGLVVPHMVRTFTGANNMRLIPLSTAVGAIFLLFADSVARASFSME
IPIGIVTSLVGAPLFAFLLFRFRQGGAY
>Mature_348_residues
MFVAKTRAIQPVQWLGIAIVVGLVGICAGRFSINPSDLFSAIQKLPSVLSSLILTGQVPDNLTQEERVILLIRFPRLLTA
LIVGAGLAVSGAVYQGVFRNPLVSPDILGVASGCMFGAAMGLILPGSSWLMVQLLAFICGLTAACAAMFMAKRFGSNSLL
LMIMTGIIVGSIFGAGLTMLKALADPYGELPAIVFWLMGSLSVSSWSTVAQLIVPVALGYGLIHTLRYRLNVLCLGDHQC
RSLGVEPARLRMVLIVTSSFIVASCVATVGSVAWIGLVVPHMVRTFTGANNMRLIPLSTAVGAIFLLFADSVARASFSME
IPIGIVTSLVGAPLFAFLLFRFRQGGAY

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=36.1702127659575, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790741, Length=324, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786805, Length=284, Percent_Identity=32.7464788732394, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788004, Length=325, Percent_Identity=32.3076923076923, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786347, Length=273, Percent_Identity=30.4029304029304, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=28.7878787878788, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36824; Mature: 36824

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVAKTRAIQPVQWLGIAIVVGLVGICAGRFSINPSDLFSAIQKLPSVLSSLILTGQVPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
NLTQEERVILLIRFPRLLTALIVGAGLAVSGAVYQGVFRNPLVSPDILGVASGCMFGAAM
CCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GLILPGSSWLMVQLLAFICGLTAACAAMFMAKRFGSNSLLLMIMTGIIVGSIFGAGLTML
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KALADPYGELPAIVFWLMGSLSVSSWSTVAQLIVPVALGYGLIHTLRYRLNVLCLGDHQC
HHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHH
RSLGVEPARLRMVLIVTSSFIVASCVATVGSVAWIGLVVPHMVRTFTGANNMRLIPLSTA
HHCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
VGAIFLLFADSVARASFSMEIPIGIVTSLVGAPLFAFLLFRFRQGGAY
HHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFVAKTRAIQPVQWLGIAIVVGLVGICAGRFSINPSDLFSAIQKLPSVLSSLILTGQVPD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
NLTQEERVILLIRFPRLLTALIVGAGLAVSGAVYQGVFRNPLVSPDILGVASGCMFGAAM
CCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GLILPGSSWLMVQLLAFICGLTAACAAMFMAKRFGSNSLLLMIMTGIIVGSIFGAGLTML
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KALADPYGELPAIVFWLMGSLSVSSWSTVAQLIVPVALGYGLIHTLRYRLNVLCLGDHQC
HHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHH
RSLGVEPARLRMVLIVTSSFIVASCVATVGSVAWIGLVVPHMVRTFTGANNMRLIPLSTA
HHCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
VGAIFLLFADSVARASFSMEIPIGIVTSLVGAPLFAFLLFRFRQGGAY
HHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]