Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 157963333

GI number: 157963333

Start: 4303008

End: 4303580

Strand: Reverse

Name: pabA [H]

Synonym: Spea_3519

Alternate gene names: 157963333

Gene position: 4303580-4303008 (Counterclockwise)

Preceding gene: 157963334

Following gene: 157963332

Centisome position: 83.17

GC content: 45.72

Gene sequence:

>573_bases
ATGATCTTAATGATCGACAACTACGACTCATTTACTTTCAATTTGGTGCAGTATTTCCAGCAGCTTGGGCAAGAGATTAT
AGTCAAGCGTAACGATGAAATCAGTCTTGAAGATATTGAGTCTCTAGCACCGAGTCACTTAGTGATCTCACCCGGCCCTT
GCACGCCTAACGAGGCTGGAATGTCGCTGTCGTTCATTGAGCATTTTGCAGGCAAGCTGCCTATTCTAGGAGTTTGTCTA
GGGCATCAGGCGATAGCGCAGGTATTTGGTGCTAATGTGGTTAGAGCCAAGCGAGTCATGCATGGTAAGACGAGTCAAAT
CATCCATACTGGTGGCGGTTTATTTGGTGGATTGAATAATCCACTTACCGTCACTCGATACCACTCCCTGCTGGTGGATG
CTATTCCTGATGGTTTTATCATGGATGCCTGGTTCGACGATCCTGTGCATGGGCGTGAAATTATGGCCATGAGTATGCCT
GCCAAGAAGATCTATGGTGTGCAGTTTCATCCTGAGTCTATATTGACCGAACAAGGCCACGAGTTGTTAGCAAACTTTAT
CAAGCTTACTTAA

Upstream 100 bases:

>100_bases
GCCCAATTCATCCACATTTAGTTTTATTGAGCATACTTAGCAGGCCCACTGGCTAAGCTTGAGGCAATAAAACACAGCGA
TATAGGTTTTTGGATCTTTT

Downstream 100 bases:

>100_bases
ATTTTTGCCCTCTGTTATAAGTATAAGCATCAAGTAAGCGAGCCTGCTCAAAATAGATGGTGTGCAGTTTCATTCTCAGC
CTCAGTATCGATATTGACCG

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIIVKRNDEISLEDIESLAPSHLVISPGPCTPNEAGMSLSFIEHFAGKLPILGVCL
GHQAIAQVFGANVVRAKRVMHGKTSQIIHTGGGLFGGLNNPLTVTRYHSLLVDAIPDGFIMDAWFDDPVHGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIKLT

Sequences:

>Translated_190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIIVKRNDEISLEDIESLAPSHLVISPGPCTPNEAGMSLSFIEHFAGKLPILGVCL
GHQAIAQVFGANVVRAKRVMHGKTSQIIHTGGGLFGGLNNPLTVTRYHSLLVDAIPDGFIMDAWFDDPVHGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIKLT
>Mature_190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIIVKRNDEISLEDIESLAPSHLVISPGPCTPNEAGMSLSFIEHFAGKLPILGVCL
GHQAIAQVFGANVVRAKRVMHGKTSQIIHTGGGLFGGLNNPLTVTRYHSLLVDAIPDGFIMDAWFDDPVHGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIKLT

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=114, Percent_Identity=35.0877192982456, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=63.4920634920635, Blast_Score=249, Evalue=8e-68,
Organism=Escherichia coli, GI1787517, Length=185, Percent_Identity=43.7837837837838, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788854, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=40.625, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=31.2796208530806, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323873, Length=147, Percent_Identity=31.2925170068027, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281365319, Length=141, Percent_Identity=30.4964539007092, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 20975; Mature: 20975

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFTFNLVQYFQQLGQEIIVKRNDEISLEDIESLAPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCC
MSLSFIEHFAGKLPILGVCLGHQAIAQVFGANVVRAKRVMHGKTSQIIHTGGGLFGGLNN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCCCEECCCCC
PLTVTRYHSLLVDAIPDGFIMDAWFDDPVHGREIMAMSMPAKKIYGVQFHPESILTEQGH
CEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCHHHHEEEEECCHHHHHHHHH
ELLANFIKLT
HHHHHHHHCC
>Mature Secondary Structure
MILMIDNYDSFTFNLVQYFQQLGQEIIVKRNDEISLEDIESLAPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCEEEEECCCCCCCCCC
MSLSFIEHFAGKLPILGVCLGHQAIAQVFGANVVRAKRVMHGKTSQIIHTGGGLFGGLNN
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEECCCCEECCCCC
PLTVTRYHSLLVDAIPDGFIMDAWFDDPVHGREIMAMSMPAKKIYGVQFHPESILTEQGH
CEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCHHHHEEEEECCHHHHHHHHH
ELLANFIKLT
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]