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The map label for this gene is dsdA [H]

Identifier: 157963263

GI number: 157963263

Start: 4216206

End: 4217531

Strand: Reverse

Name: dsdA [H]

Synonym: Spea_3449

Alternate gene names: 157963263

Gene position: 4217531-4216206 (Counterclockwise)

Preceding gene: 157963264

Following gene: 157963257

Centisome position: 81.5

GC content: 51.06

Gene sequence:

>1326_bases
ATGATGAACACCGAACAACTGATAAACGACTTCCCTTTGCTGACTCAGCTTATCAAGCTTGAAGAAGTTAGCTGGTTTGA
AACCAAGGCGACCAACTTAGCCGAAGCATTACCTTATGTTGGCTTAGATAGCACAGATGTGGCCGATGCCAGCGCACGTT
TACAGCGCTTTGCACCTTACCTAGCGCTAGCCTTCCCTGAGACGGCGGCATCGAATGGCATTATCGAGTCTGAAGTGGTG
GCCATTCCACAGATGAAGCAAGCGCTAGAAGCTAAATACGGCCAGAAGATCGCAGGCCAGCTGATGTTGAAAAAAGACAG
CCATCTGCCAATATCTGGTTCTATCAAGGCGCGTGGCGGCATTTATGAAGTACTGACCCATGCTGAAAAACTAGCGATTG
CTGCGGGTAAGCTTAAAGAGTCTGACGACTATCAAATGCTGTTCACTGAAGAGATGAAGAGCTTCTTTAACGGTTACAGC
ATTGCGGTAGGTTCGACCGGTAACTTAGGCATGTCTATTGGTATCATGAGTGCCAAGCTTGGTTTCAACGTGAGCGTGCA
TATGTCGGCAGATGCTCGCCAGTGGAAGAAAGACAAGTTACGTAGCCACGGCGTGAATGTATTTGAATATGAGCAAGATT
ACGGCGTAGCGGTTGAGCAAGGTCGTAAGGCGGCTGAATCTGATGCTAATTGCTTCTTTATCGACGATGAAAACTCGCGC
ACGCTATTTTTAGGCTACTCGGTTGCCGGTGAGCGTTTGAAGGCACAGTTTGACGCAGCTGACATTAAGGTTGATAGCGA
GCACCCACTGTTTGTTTACCTGCCTTGTGGTGTGGGCGGTGGCCCTGGTGGTGTGGCGTTTGGTCTTAAGTTAGCCTTCG
GTGATAACGTTCATTGCTTCTTCGCCGAGCCGACACATTCACCTTGTATGTTACTAGGGGTGCACACGGGTCTGCATGAC
GAAATCGCCGTGCAGGACTTAGGCATCGACAACGTGACAGCTGCCGACGGTTTAGCGGTAGGCCGCGCCTCAGGTTTCGT
TGGCCGCGCCATGGAGCGTATGCTAGATGGTTACTACACCTTAAGCGATCAGCATATGTATGACCTACTTGGCCTATTGG
CTAAGAGTGAAGGTATTGAACTTGAACCATCGGCCCTTGCGGGTATGCCGGGCGCACTTAGGGTGAGCGGCGATAGCGAG
TATCAGGCGCGTATGGGGCTAACACCTGAGATGATGAGCAATGCGACTCACGTAGTGTGGGCGACAGGCGGCGGCATGGT
ACCAGCAGCAGAGATGGCGAAATACCTAGGGCAATCGGCTAGCTAA

Upstream 100 bases:

>100_bases
ATTTATGTATTACACCAGCGCGACCTTTATTGCCTCACTTGTGGCACTGGCTGCGACTTTTGCACTGTCTTATGTTATTT
AATCCTAAAGGGGAACTGAA

Downstream 100 bases:

>100_bases
TTTTTCATATAAGTTCGAGTTAGTAGAGTTAGTAGAGTTAGTAGAGCTAGATTACTAACGTCAAAAGAGCAGAGCTTGCA
GGGCTGATGATATTCGGCCT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MMNTEQLINDFPLLTQLIKLEEVSWFETKATNLAEALPYVGLDSTDVADASARLQRFAPYLALAFPETAASNGIIESEVV
AIPQMKQALEAKYGQKIAGQLMLKKDSHLPISGSIKARGGIYEVLTHAEKLAIAAGKLKESDDYQMLFTEEMKSFFNGYS
IAVGSTGNLGMSIGIMSAKLGFNVSVHMSADARQWKKDKLRSHGVNVFEYEQDYGVAVEQGRKAAESDANCFFIDDENSR
TLFLGYSVAGERLKAQFDAADIKVDSEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVHTGLHD
EIAVQDLGIDNVTAADGLAVGRASGFVGRAMERMLDGYYTLSDQHMYDLLGLLAKSEGIELEPSALAGMPGALRVSGDSE
YQARMGLTPEMMSNATHVVWATGGGMVPAAEMAKYLGQSAS

Sequences:

>Translated_441_residues
MMNTEQLINDFPLLTQLIKLEEVSWFETKATNLAEALPYVGLDSTDVADASARLQRFAPYLALAFPETAASNGIIESEVV
AIPQMKQALEAKYGQKIAGQLMLKKDSHLPISGSIKARGGIYEVLTHAEKLAIAAGKLKESDDYQMLFTEEMKSFFNGYS
IAVGSTGNLGMSIGIMSAKLGFNVSVHMSADARQWKKDKLRSHGVNVFEYEQDYGVAVEQGRKAAESDANCFFIDDENSR
TLFLGYSVAGERLKAQFDAADIKVDSEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVHTGLHD
EIAVQDLGIDNVTAADGLAVGRASGFVGRAMERMLDGYYTLSDQHMYDLLGLLAKSEGIELEPSALAGMPGALRVSGDSE
YQARMGLTPEMMSNATHVVWATGGGMVPAAEMAKYLGQSAS
>Mature_441_residues
MMNTEQLINDFPLLTQLIKLEEVSWFETKATNLAEALPYVGLDSTDVADASARLQRFAPYLALAFPETAASNGIIESEVV
AIPQMKQALEAKYGQKIAGQLMLKKDSHLPISGSIKARGGIYEVLTHAEKLAIAAGKLKESDDYQMLFTEEMKSFFNGYS
IAVGSTGNLGMSIGIMSAKLGFNVSVHMSADARQWKKDKLRSHGVNVFEYEQDYGVAVEQGRKAAESDANCFFIDDENSR
TLFLGYSVAGERLKAQFDAADIKVDSEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVHTGLHD
EIAVQDLGIDNVTAADGLAVGRASGFVGRAMERMLDGYYTLSDQHMYDLLGLLAKSEGIELEPSALAGMPGALRVSGDSE
YQARMGLTPEMMSNATHVVWATGGGMVPAAEMAKYLGQSAS

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=437, Percent_Identity=73.4553775743707, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47412; Mature: 47412

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTEQLINDFPLLTQLIKLEEVSWFETKATNLAEALPYVGLDSTDVADASARLQRFAPY
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCH
LALAFPETAASNGIIESEVVAIPQMKQALEAKYGQKIAGQLMLKKDSHLPISGSIKARGG
HEEECCCHHCCCCCCHHHEEECHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
IYEVLTHAEKLAIAAGKLKESDDYQMLFTEEMKSFFNGYSIAVGSTGNLGMSIGIMSAKL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEC
GFNVSVHMSADARQWKKDKLRSHGVNVFEYEQDYGVAVEQGRKAAESDANCFFIDDENSR
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCHHHCCCCCEEEEECCCCC
TLFLGYSVAGERLKAQFDAADIKVDSEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCF
EEEEEECCCCCHHHHEECCCEEEECCCCCEEEEEECCCCCCCCCEEEEEEEEECCCEEEE
FAEPTHSPCMLLGVHTGLHDEIAVQDLGIDNVTAADGLAVGRASGFVGRAMERMLDGYYT
EECCCCCCEEEEEECCCCCCCHHHEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCEEE
LSDQHMYDLLGLLAKSEGIELEPSALAGMPGALRVSGDSEYQARMGLTPEMMSNATHVVW
ECCCHHHHHHHHHHCCCCCEECCHHHCCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEE
ATGGGMVPAAEMAKYLGQSAS
ECCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MMNTEQLINDFPLLTQLIKLEEVSWFETKATNLAEALPYVGLDSTDVADASARLQRFAPY
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCH
LALAFPETAASNGIIESEVVAIPQMKQALEAKYGQKIAGQLMLKKDSHLPISGSIKARGG
HEEECCCHHCCCCCCHHHEEECHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCC
IYEVLTHAEKLAIAAGKLKESDDYQMLFTEEMKSFFNGYSIAVGSTGNLGMSIGIMSAKL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEC
GFNVSVHMSADARQWKKDKLRSHGVNVFEYEQDYGVAVEQGRKAAESDANCFFIDDENSR
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCHHHCCCCCEEEEECCCCC
TLFLGYSVAGERLKAQFDAADIKVDSEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCF
EEEEEECCCCCHHHHEECCCEEEECCCCCEEEEEECCCCCCCCCEEEEEEEEECCCEEEE
FAEPTHSPCMLLGVHTGLHDEIAVQDLGIDNVTAADGLAVGRASGFVGRAMERMLDGYYT
EECCCCCCEEEEEECCCCCCCHHHEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCEEE
LSDQHMYDLLGLLAKSEGIELEPSALAGMPGALRVSGDSEYQARMGLTPEMMSNATHVVW
ECCCHHHHHHHHHHCCCCCEECCHHHCCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEE
ATGGGMVPAAEMAKYLGQSAS
ECCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA