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The map label for this gene is 157963239

Identifier: 157963239

GI number: 157963239

Start: 4186107

End: 4187489

Strand: Reverse

Name: 157963239

Synonym: Spea_3425

Alternate gene names: NA

Gene position: 4187489-4186107 (Counterclockwise)

Preceding gene: 157963240

Following gene: 157963238

Centisome position: 80.92

GC content: 44.76

Gene sequence:

>1383_bases
ATGTCTGAACCGACAGCCTTAAGTCTTATCCCACCAGTGGTGGTTTTGGTGTTAGCGATTGTGCTACGCCGCCCAATTCT
CTCTTTGATTATCGGTGCATTAGTTGGTTTGGCTATGTATGAGCCAGAGAATCTATTGACTAATTTTGCTGATACGTCTT
TGTCCGTTATGGCCGATGAAACGATCGGTTGGTTAATTTTAGTCTGTGGCGGCTTCGGTGCCTTGATTGCTCTACTTGTG
CGTACAGGTGGATCGATGGCGTTCGGTCGTTATGCGCTAAAGTTTGCGAATGGACAAAAGTCATCACTGTTTATGACCTT
TATTTTAGGTGTGATTATCTTTATTGATGATTACCTCAATGCGCTAACGGTTGGTTCAACCATGAAGCGCGTAACCGATA
AGTTTAAAGTCTCGCGTGAGATGTTAGCTTATGTGGTCGACTCAACTGCTGCACCTGTTTGCGTGCTTGTGCCATTATCA
ACATGGGCGGTATTTTTTGGTGGTTTGCTAGTCGATAACGGTATTGCTGCTGAAGGTCAAGGTGTCGCAGTTTATATGCA
AGCGATTCCTTATATGTTGTACGCATGGCTTGCTGTGGCGATGGTATTGTTGGTTATCTTAGGCATAGTACCAGCGTTTG
GGCCGATGAAAAAAGCGCAATTGGCTGCCGCTCAAGGCGAACCTGCGATTAAGCAGATGGATTTAGATGAAGTACAAACC
TCTGATGAATATGCACTAAAAGCCATTGAGGATGAGTTTAAGCACGCCGATGATAGCGGTAAGCTGCATAATTTCTTTGT
ACCAATTTTATTGTTAGTTGGCTTTACCGTTTATTTTGACATCGATGTATTAAAAGGTTTGATTGCCACATTAGCGGTCA
CCTTGCCTTATTATGGGCTGCAAAAGCTGATGCCATTATCAGAGATGATGGAGCAGATGATTGATGGCTTTAAGAATATG
CTGCCAGCAATAGGTACGGTAATCGCGGCGTTTATTTTTAAAGACGTGTGCGACAAACTAATGTTGCCACAGTATGTGAT
AGAGAGCTTAAGCCCGTTTATGACACCGCAATTGCTACCCGCAGTGGTGTTCTTAAGTATGTCGATTTTGGCATTTGCGA
CCGGCTCTAGCTGGGGGATTTTCGCCGTGTCTATCCCAATCGTGATGCCATTGGCTCAATCGGTTGATGCAAATATTCCA
TTAGTGATTGGCGCGTTACTGTCGGCATCATCATTTGGCAGTCAAGCGTGTTTCTATTCAGACTCCACAGTGCTCGCGGC
GCAAGGCTCGGGCTGTAACTTAGTCAGTCACGCAGTGACTCAGCTGCCTTATGCACTGATTGCAGCTGGTTTAACCTTTG
TTGGTTTCTTACTAATGGCATAA

Upstream 100 bases:

>100_bases
AGGTATCTCAACAGTAGAGCAGCAATTAGACTCGACAAATAATTGTTTGAGTTTGGTGATTAATTGCCATTTTGGCACTT
CATTATAAGGACCTTAGCGC

Downstream 100 bases:

>100_bases
GTCTTACTAGATTAGTTGTAGAAGTAACTAGTTACTTGCCATTTAAAAAGGCTGCACTTTTTGTGCAGCCTTTTTTATCT
ACAGAAACCTTATAGTGTCT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLAMYEPENLLTNFADTSLSVMADETIGWLILVCGGFGALIALLV
RTGGSMAFGRYALKFANGQKSSLFMTFILGVIIFIDDYLNALTVGSTMKRVTDKFKVSREMLAYVVDSTAAPVCVLVPLS
TWAVFFGGLLVDNGIAAEGQGVAVYMQAIPYMLYAWLAVAMVLLVILGIVPAFGPMKKAQLAAAQGEPAIKQMDLDEVQT
SDEYALKAIEDEFKHADDSGKLHNFFVPILLLVGFTVYFDIDVLKGLIATLAVTLPYYGLQKLMPLSEMMEQMIDGFKNM
LPAIGTVIAAFIFKDVCDKLMLPQYVIESLSPFMTPQLLPAVVFLSMSILAFATGSSWGIFAVSIPIVMPLAQSVDANIP
LVIGALLSASSFGSQACFYSDSTVLAAQGSGCNLVSHAVTQLPYALIAAGLTFVGFLLMA

Sequences:

>Translated_460_residues
MSEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLAMYEPENLLTNFADTSLSVMADETIGWLILVCGGFGALIALLV
RTGGSMAFGRYALKFANGQKSSLFMTFILGVIIFIDDYLNALTVGSTMKRVTDKFKVSREMLAYVVDSTAAPVCVLVPLS
TWAVFFGGLLVDNGIAAEGQGVAVYMQAIPYMLYAWLAVAMVLLVILGIVPAFGPMKKAQLAAAQGEPAIKQMDLDEVQT
SDEYALKAIEDEFKHADDSGKLHNFFVPILLLVGFTVYFDIDVLKGLIATLAVTLPYYGLQKLMPLSEMMEQMIDGFKNM
LPAIGTVIAAFIFKDVCDKLMLPQYVIESLSPFMTPQLLPAVVFLSMSILAFATGSSWGIFAVSIPIVMPLAQSVDANIP
LVIGALLSASSFGSQACFYSDSTVLAAQGSGCNLVSHAVTQLPYALIAAGLTFVGFLLMA
>Mature_459_residues
SEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLAMYEPENLLTNFADTSLSVMADETIGWLILVCGGFGALIALLVR
TGGSMAFGRYALKFANGQKSSLFMTFILGVIIFIDDYLNALTVGSTMKRVTDKFKVSREMLAYVVDSTAAPVCVLVPLST
WAVFFGGLLVDNGIAAEGQGVAVYMQAIPYMLYAWLAVAMVLLVILGIVPAFGPMKKAQLAAAQGEPAIKQMDLDEVQTS
DEYALKAIEDEFKHADDSGKLHNFFVPILLLVGFTVYFDIDVLKGLIATLAVTLPYYGLQKLMPLSEMMEQMIDGFKNML
PAIGTVIAAFIFKDVCDKLMLPQYVIESLSPFMTPQLLPAVVFLSMSILAFATGSSWGIFAVSIPIVMPLAQSVDANIPL
VIGALLSASSFGSQACFYSDSTVLAAQGSGCNLVSHAVTQLPYALIAAGLTFVGFLLMA

Specific function: Unknown

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 49195; Mature: 49064

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLAMYEPENLLTNFADTSLSVMADE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH
TIGWLILVCGGFGALIALLVRTGGSMAFGRYALKFANGQKSSLFMTFILGVIIFIDDYLN
HHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ALTVGSTMKRVTDKFKVSREMLAYVVDSTAAPVCVLVPLSTWAVFFGGLLVDNGIAAEGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCC
GVAVYMQAIPYMLYAWLAVAMVLLVILGIVPAFGPMKKAQLAAAQGEPAIKQMDLDEVQT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCHHHHHC
SDEYALKAIEDEFKHADDSGKLHNFFVPILLLVGFTVYFDIDVLKGLIATLAVTLPYYGL
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKLMPLSEMMEQMIDGFKNMLPAIGTVIAAFIFKDVCDKLMLPQYVIESLSPFMTPQLLP
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHCCHHHHH
AVVFLSMSILAFATGSSWGIFAVSIPIVMPLAQSVDANIPLVIGALLSASSFGSQACFYS
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEC
DSTVLAAQGSGCNLVSHAVTQLPYALIAAGLTFVGFLLMA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEPTALSLIPPVVVLVLAIVLRRPILSLIIGALVGLAMYEPENLLTNFADTSLSVMADE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH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CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]