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The map label for this gene is yiaV [H]

Identifier: 157963235

GI number: 157963235

Start: 4180221

End: 4181288

Strand: Reverse

Name: yiaV [H]

Synonym: Spea_3421

Alternate gene names: 157963235

Gene position: 4181288-4180221 (Counterclockwise)

Preceding gene: 157963237

Following gene: 157963234

Centisome position: 80.8

GC content: 48.88

Gene sequence:

>1068_bases
ATGCAAACCGCAGAACATGCTTTTCGTCGTTGGATGCAAAGCTTGCTTGTTATCTTCATCATTTTGATTGGCTATATCGT
TATTGCCGACCGCTATGCACCACTCACTACAGAGAGCCGAGTGCAAGGTTACGTGATCCAAATTGCCCCGGAAGTCACAG
GAAGCGTCACTGAGGTTCAGGTGTACAATAATCAGAAGTTAACCAAGGGAGATAAGCTATTTCGTATCGATGCGCGTAAG
TATCAGCTTGCGTTGGAGAAAGCCCTGTTGGCGCTAGAGCAGGCCCATGAACAGGAGGAGGCTATGTACGCCAAAGTGGA
GGTGGCTGAGGCAAAAGTCGCCACTAATCAAGCCGCTTTTGATAATGCCAGAAGTGAGTATCGACGGATCAGTCAGCTGG
CGAAGCAAAAGCTAGTCTCGGTGTCTATGTTAGATAACGCTCTAGCAAATAATAATGCATCTGGAGCTAATCTACGCGCT
GCTCAGCAGGAGCTGCGGGCATTAACCGTGCAGCTTGGTAGTCAACCTGGGCAGAGTAGTGGTGTCCGTTCAGCTCTAAA
TGCACTTAAACAGGCGAAGCTAGATCTTTCCCATACTCAAGTGGTTGCACCGAGTGATGGCGTGGTTACCAACTTGCAAT
TGGAGGTAGGGAGCATTGCCAATGCCAATATGCCGTTACTGACTTTTATTCCTACAGACTCACTCTGGGTTGCCGCAGAC
TTTCGTGAAAAAGCAGTCGCTCGAATAAACAGTCACTCACGTGGGCTGGTTGCATTTGATGCCTTTCCGGGGCGGGTATT
TGCTTTAAATGTGCAGAGCCGTGACTTTGGGGTGGCGGCGGCTCAGCAAAGCCCTAACGGCCAATTGACTCAGGTTGAGA
CTAATAATCGTTGGGTGCGGGATGCCCAGCGAGTGCGGATTAACCTGAGCAGCCCAAGTGCATTACCTAATCCGCTATTT
GTTGGCTCTCGTGCGAGTGTGGTGATCTATCCAGATGATAATGCCTTTTGGAGCTTGTTAGCCAAGACTCAAATTAAGAT
CGTGAGTTGGCTTCACTTCATTTATTAA

Upstream 100 bases:

>100_bases
TGTCCTACCTATAGGTCTCAAGTGTGCTATTTGTCATTCTATTTAATCTAATTAGCAATATCTATAATAGTCGCCCCTCA
GATAGACCTTGGACTCATTC

Downstream 100 bases:

>100_bases
CATTAGTTATTAACATTCGTTATTAACTTTGCTGACGACCAGAGGCTACATTTTGCAATTCGAGACTTTGAGAAAAACCC
AACGGATCTGGTTTGGTTGT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQTAEHAFRRWMQSLLVIFIILIGYIVIADRYAPLTTESRVQGYVIQIAPEVTGSVTEVQVYNNQKLTKGDKLFRIDARK
YQLALEKALLALEQAHEQEEAMYAKVEVAEAKVATNQAAFDNARSEYRRISQLAKQKLVSVSMLDNALANNNASGANLRA
AQQELRALTVQLGSQPGQSSGVRSALNALKQAKLDLSHTQVVAPSDGVVTNLQLEVGSIANANMPLLTFIPTDSLWVAAD
FREKAVARINSHSRGLVAFDAFPGRVFALNVQSRDFGVAAAQQSPNGQLTQVETNNRWVRDAQRVRINLSSPSALPNPLF
VGSRASVVIYPDDNAFWSLLAKTQIKIVSWLHFIY

Sequences:

>Translated_355_residues
MQTAEHAFRRWMQSLLVIFIILIGYIVIADRYAPLTTESRVQGYVIQIAPEVTGSVTEVQVYNNQKLTKGDKLFRIDARK
YQLALEKALLALEQAHEQEEAMYAKVEVAEAKVATNQAAFDNARSEYRRISQLAKQKLVSVSMLDNALANNNASGANLRA
AQQELRALTVQLGSQPGQSSGVRSALNALKQAKLDLSHTQVVAPSDGVVTNLQLEVGSIANANMPLLTFIPTDSLWVAAD
FREKAVARINSHSRGLVAFDAFPGRVFALNVQSRDFGVAAAQQSPNGQLTQVETNNRWVRDAQRVRINLSSPSALPNPLF
VGSRASVVIYPDDNAFWSLLAKTQIKIVSWLHFIY
>Mature_355_residues
MQTAEHAFRRWMQSLLVIFIILIGYIVIADRYAPLTTESRVQGYVIQIAPEVTGSVTEVQVYNNQKLTKGDKLFRIDARK
YQLALEKALLALEQAHEQEEAMYAKVEVAEAKVATNQAAFDNARSEYRRISQLAKQKLVSVSMLDNALANNNASGANLRA
AQQELRALTVQLGSQPGQSSGVRSALNALKQAKLDLSHTQVVAPSDGVVTNLQLEVGSIANANMPLLTFIPTDSLWVAAD
FREKAVARINSHSRGLVAFDAFPGRVFALNVQSRDFGVAAAQQSPNGQLTQVETNNRWVRDAQRVRINLSSPSALPNPLF
VGSRASVVIYPDDNAFWSLLAKTQIKIVSWLHFIY

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=347, Percent_Identity=28.8184438040346, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790519, Length=321, Percent_Identity=31.7757009345794, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790024, Length=340, Percent_Identity=29.1176470588235, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789041, Length=322, Percent_Identity=26.7080745341615, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789637, Length=328, Percent_Identity=26.219512195122, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788711, Length=337, Percent_Identity=27.0029673590504, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081951, Length=282, Percent_Identity=25.177304964539, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39161; Mature: 39161

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAEHAFRRWMQSLLVIFIILIGYIVIADRYAPLTTESRVQGYVIQIAPEVTGSVTEVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEE
VYNNQKLTKGDKLFRIDARKYQLALEKALLALEQAHEQEEAMYAKVEVAEAKVATNQAAF
EECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCHHHH
DNARSEYRRISQLAKQKLVSVSMLDNALANNNASGANLRAAQQELRALTVQLGSQPGQSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
GVRSALNALKQAKLDLSHTQVVAPSDGVVTNLQLEVGSIANANMPLLTFIPTDSLWVAAD
HHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEEEECCCCEEEEEC
FREKAVARINSHSRGLVAFDAFPGRVFALNVQSRDFGVAAAQQSPNGQLTQVETNNRWVR
HHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCCHHC
DAQRVRINLSSPSALPNPLFVGSRASVVIYPDDNAFWSLLAKTQIKIVSWLHFIY
CCEEEEEEECCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQTAEHAFRRWMQSLLVIFIILIGYIVIADRYAPLTTESRVQGYVIQIAPEVTGSVTEVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEE
VYNNQKLTKGDKLFRIDARKYQLALEKALLALEQAHEQEEAMYAKVEVAEAKVATNQAAF
EECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCHHHH
DNARSEYRRISQLAKQKLVSVSMLDNALANNNASGANLRAAQQELRALTVQLGSQPGQSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCH
GVRSALNALKQAKLDLSHTQVVAPSDGVVTNLQLEVGSIANANMPLLTFIPTDSLWVAAD
HHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEECCCCCCCCCEEEEECCCCEEEEEC
FREKAVARINSHSRGLVAFDAFPGRVFALNVQSRDFGVAAAQQSPNGQLTQVETNNRWVR
HHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCCHHC
DAQRVRINLSSPSALPNPLFVGSRASVVIYPDDNAFWSLLAKTQIKIVSWLHFIY
CCEEEEEEECCCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]