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The map label for this gene is cobC [H]

Identifier: 157963198

GI number: 157963198

Start: 4131919

End: 4132533

Strand: Reverse

Name: cobC [H]

Synonym: Spea_3383

Alternate gene names: 157963198

Gene position: 4132533-4131919 (Counterclockwise)

Preceding gene: 157963200

Following gene: 157963197

Centisome position: 79.86

GC content: 49.76

Gene sequence:

>615_bases
ATGCAAACCACAAGGGTGATATTGCTTAGACATGGTGAATGCGAAGGTGGCAATATTTTGCGCGGCCAGATCGATGTCGC
TTTAACTGAGCAGGGTAAGCGGCAGATGCAAAGCGTGCTTTGCGGCCTAAAGAGCCCCGGTTCTACACCTGATGTGGTGC
TGAGCTCACCACTTATTCGCTGCGCTAACCTCGCTGAAGAATTTGCATTGACTCAGGGGAGCCCTTATGCGGTAGAGGCC
GCCTTTAAAGAGCTAAACTTTGGCGATTGGGATGGGCAAACATTTGATGTGCTTTATCAATCTCATGCCGCAGCATTAGA
TGCTTACTGGGCTAATCCTTGGTTGGCAGCGCCGCCTAATGGCGAATCAATGCAGGACTTTGAAGCGCGTATTGAGCGCG
CTTGGCAAGCTATGTTTGAGCAACATCAGGGTAAACAGATATTACTGGTGACTCACGGCGGCGTGATGCGTCACTTGATG
GCAAAAGCGCTAGGGGTAAAGCAAGCGGCAGGCTTTTATACCTCACTTCAATTACCCTATGCAGCCAAGGCGGAGATTGA
TGTGCTGCACGATGAAAACGGACAGCAGTTTTTAACTCTGCATTGGGGTAAATAA

Upstream 100 bases:

>100_bases
TGATAAAAAGTGCAAGTGCTAAAGCATGATACTTTTTCAGCATTAAAAGCCAATGAATTTTATGTAAGTGGCTGATAAAT
AATAGAGGTAAATGGTAATC

Downstream 100 bases:

>100_bases
GGTCTCAGGTTTTAAAGAAGGTGCTAGGTCCTAGGAAAAGAGCAGGTTCTAGGCAAAGCAAAGACGGTAAAGCTAAGACG
ATTAAAGCAAAGCCGAACGG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MQTTRVILLRHGECEGGNILRGQIDVALTEQGKRQMQSVLCGLKSPGSTPDVVLSSPLIRCANLAEEFALTQGSPYAVEA
AFKELNFGDWDGQTFDVLYQSHAAALDAYWANPWLAAPPNGESMQDFEARIERAWQAMFEQHQGKQILLVTHGGVMRHLM
AKALGVKQAAGFYTSLQLPYAAKAEIDVLHDENGQQFLTLHWGK

Sequences:

>Translated_204_residues
MQTTRVILLRHGECEGGNILRGQIDVALTEQGKRQMQSVLCGLKSPGSTPDVVLSSPLIRCANLAEEFALTQGSPYAVEA
AFKELNFGDWDGQTFDVLYQSHAAALDAYWANPWLAAPPNGESMQDFEARIERAWQAMFEQHQGKQILLVTHGGVMRHLM
AKALGVKQAAGFYTSLQLPYAAKAEIDVLHDENGQQFLTLHWGK
>Mature_204_residues
MQTTRVILLRHGECEGGNILRGQIDVALTEQGKRQMQSVLCGLKSPGSTPDVVLSSPLIRCANLAEEFALTQGSPYAVEA
AFKELNFGDWDGQTFDVLYQSHAAALDAYWANPWLAAPPNGESMQDFEARIERAWQAMFEQHQGKQILLVTHGGVMRHLM
AKALGVKQAAGFYTSLQLPYAAKAEIDVLHDENGQQFLTLHWGK

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1790856, Length=163, Percent_Identity=30.0613496932515, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 22540; Mature: 22540

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTRVILLRHGECEGGNILRGQIDVALTEQGKRQMQSVLCGLKSPGSTPDVVLSSPLIR
CCCEEEEEEECCCCCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHH
CANLAEEFALTQGSPYAVEAAFKELNFGDWDGQTFDVLYQSHAAALDAYWANPWLAAPPN
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCC
GESMQDFEARIERAWQAMFEQHQGKQILLVTHGGVMRHLMAKALGVKQAAGFYTSLQLPY
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCHHHHCCCEEEEECCC
AAKAEIDVLHDENGQQFLTLHWGK
CCCCEEEEEECCCCCEEEEEECCC
>Mature Secondary Structure
MQTTRVILLRHGECEGGNILRGQIDVALTEQGKRQMQSVLCGLKSPGSTPDVVLSSPLIR
CCCEEEEEEECCCCCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHH
CANLAEEFALTQGSPYAVEAAFKELNFGDWDGQTFDVLYQSHAAALDAYWANPWLAAPPN
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCC
GESMQDFEARIERAWQAMFEQHQGKQILLVTHGGVMRHLMAKALGVKQAAGFYTSLQLPY
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCHHHHCCCEEEEECCC
AAKAEIDVLHDENGQQFLTLHWGK
CCCCEEEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]