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The map label for this gene is fecC [C]

Identifier: 157963196

GI number: 157963196

Start: 4129167

End: 4130222

Strand: Reverse

Name: fecC [C]

Synonym: Spea_3381

Alternate gene names: 157963196

Gene position: 4130222-4129167 (Counterclockwise)

Preceding gene: 157963197

Following gene: 157963195

Centisome position: 79.82

GC content: 50.47

Gene sequence:

>1056_bases
ATGAGTAAGCCTTCAGCTCGCCAAGTCGGCGCAGTATTGAGTCAGCGGCGTCCTATCGAGTACCTAGTATTTTCCTTGTT
GCTCTTTATAACTTTGCTTACCCCTTTTGCGGCGACAAGTTTTGGCGCTGCAACAGTTAGTGCCGTTGATGTTTTTAATG
TGCTGGCTTATAAGCTGCTGAATCTTGGTGAGTCACTGGGGGTTAGAGAGCGGATTATTTGGGAGCTGCGTTTACCGCGA
GTGTTACTGGCCTTTATCGCCGGAGCAGGGCTCTCGATTGCTGGTAGTGTGTTGCAAACAGTGACTCGAAATCCGCTAGC
AGACCCTTATCTGTTTGGGATCTCATCCGGCGCCTCTTTCGGCGCTGTAGTGGCGTTAACCCTATTTAGCCAAAGTATGC
TTTGGTTAAGCCTGCCCGTAGGAGCCTTTATTGGCGCTAGCTTGTCGGTGGTGATGGTGCTGAGCCTGTGCGGCCGCAAC
TTAAGTACCCAGGTTGAACGTATGTTGCTCTCCGGCGTGGCTATCTCGTTTATGTTTGGCGCGATGGCAAGCCTGATGCT
GTATTTCTCTAGCCCACAAGCTGCGGCCTCTGTGCTGTTTTGGACCTTAGGCAGTTTTGCCAAAGCCAGCTGGCAAGGCC
TATGGTTGCCAGCCGGAAGCGTTATCTTATCTACCCTAATCATCTTACTTAATAAGCGCCAGATTGTGGCCATGCGTGCG
GGCGATGAAACCGCCCATACCCTAGGGATTAATGTCGGCCACTTGCGTCTCAATATGTTGCTTCTGTGCTCGCTTATCAC
CGCGATACTGGTCGCAAATTGTGGCGGTATCGGCTTTATCGGCTTAATGGTGCCCCATACGGTGCGTTTACTGTTTCCGG
GACGCTACCCCCTGTTATTAACGGCGCTGGTGGGAGGGCTATTTATGGTTTGGGTCGATGTATTAGCCCGAACATTATTG
AGTTATCAAGAATTGCCTGTGGGGATCATTACCTCGGTGATGGGCAGTATTTTCTTTCTATTTATTTTAGGCAGTCGCAG
CGGTAAACGTATTTAG

Upstream 100 bases:

>100_bases
CAACATGGCAACCCACTGATCAGTTACTTTTATGGCTATGATGCGAGCCTTGCGGATTCCACTCAACATTCGATAGAAAA
TCCTATTGCAGGAGGGCTAG

Downstream 100 bases:

>100_bases
CGAGCCACATTTATAACATCCTTATTGAGTGGTTGAGGGGAAACAATGATGTTTGATATTAAAGCTGTAAATACTGAATT
TGATGATGAAATTCAGCAAA

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSKPSARQVGAVLSQRRPIEYLVFSLLLFITLLTPFAATSFGAATVSAVDVFNVLAYKLLNLGESLGVRERIIWELRLPR
VLLAFIAGAGLSIAGSVLQTVTRNPLADPYLFGISSGASFGAVVALTLFSQSMLWLSLPVGAFIGASLSVVMVLSLCGRN
LSTQVERMLLSGVAISFMFGAMASLMLYFSSPQAAASVLFWTLGSFAKASWQGLWLPAGSVILSTLIILLNKRQIVAMRA
GDETAHTLGINVGHLRLNMLLLCSLITAILVANCGGIGFIGLMVPHTVRLLFPGRYPLLLTALVGGLFMVWVDVLARTLL
SYQELPVGIITSVMGSIFFLFILGSRSGKRI

Sequences:

>Translated_351_residues
MSKPSARQVGAVLSQRRPIEYLVFSLLLFITLLTPFAATSFGAATVSAVDVFNVLAYKLLNLGESLGVRERIIWELRLPR
VLLAFIAGAGLSIAGSVLQTVTRNPLADPYLFGISSGASFGAVVALTLFSQSMLWLSLPVGAFIGASLSVVMVLSLCGRN
LSTQVERMLLSGVAISFMFGAMASLMLYFSSPQAAASVLFWTLGSFAKASWQGLWLPAGSVILSTLIILLNKRQIVAMRA
GDETAHTLGINVGHLRLNMLLLCSLITAILVANCGGIGFIGLMVPHTVRLLFPGRYPLLLTALVGGLFMVWVDVLARTLL
SYQELPVGIITSVMGSIFFLFILGSRSGKRI
>Mature_350_residues
SKPSARQVGAVLSQRRPIEYLVFSLLLFITLLTPFAATSFGAATVSAVDVFNVLAYKLLNLGESLGVRERIIWELRLPRV
LLAFIAGAGLSIAGSVLQTVTRNPLADPYLFGISSGASFGAVVALTLFSQSMLWLSLPVGAFIGASLSVVMVLSLCGRNL
STQVERMLLSGVAISFMFGAMASLMLYFSSPQAAASVLFWTLGSFAKASWQGLWLPAGSVILSTLIILLNKRQIVAMRAG
DETAHTLGINVGHLRLNMLLLCSLITAILVANCGGIGFIGLMVPHTVRLLFPGRYPLLLTALVGGLFMVWVDVLARTLLS
YQELPVGIITSVMGSIFFLFILGSRSGKRI

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=303, Percent_Identity=33.003300330033, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790740, Length=271, Percent_Identity=37.2693726937269, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786347, Length=273, Percent_Identity=33.6996336996337, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=32.9710144927536, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786804, Length=310, Percent_Identity=31.2903225806452, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786805, Length=280, Percent_Identity=31.0714285714286, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37559; Mature: 37427

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPSARQVGAVLSQRRPIEYLVFSLLLFITLLTPFAATSFGAATVSAVDVFNVLAYKLL
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NLGESLGVRERIIWELRLPRVLLAFIAGAGLSIAGSVLQTVTRNPLADPYLFGISSGASF
HCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCH
GAVVALTLFSQSMLWLSLPVGAFIGASLSVVMVLSLCGRNLSTQVERMLLSGVAISFMFG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AMASLMLYFSSPQAAASVLFWTLGSFAKASWQGLWLPAGSVILSTLIILLNKRQIVAMRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCEEEEEEC
GDETAHTLGINVGHLRLNMLLLCSLITAILVANCGGIGFIGLMVPHTVRLLFPGRYPLLL
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TALVGGLFMVWVDVLARTLLSYQELPVGIITSVMGSIFFLFILGSRSGKRI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKPSARQVGAVLSQRRPIEYLVFSLLLFITLLTPFAATSFGAATVSAVDVFNVLAYKLL
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NLGESLGVRERIIWELRLPRVLLAFIAGAGLSIAGSVLQTVTRNPLADPYLFGISSGASF
HCCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCH
GAVVALTLFSQSMLWLSLPVGAFIGASLSVVMVLSLCGRNLSTQVERMLLSGVAISFMFG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AMASLMLYFSSPQAAASVLFWTLGSFAKASWQGLWLPAGSVILSTLIILLNKRQIVAMRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHCCCEEEEEEC
GDETAHTLGINVGHLRLNMLLLCSLITAILVANCGGIGFIGLMVPHTVRLLFPGRYPLLL
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
TALVGGLFMVWVDVLARTLLSYQELPVGIITSVMGSIFFLFILGSRSGKRI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]