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The map label for this gene is cobT [H]

Identifier: 157963195

GI number: 157963195

Start: 4128090

End: 4129121

Strand: Reverse

Name: cobT [H]

Synonym: Spea_3380

Alternate gene names: 157963195

Gene position: 4129121-4128090 (Counterclockwise)

Preceding gene: 157963196

Following gene: 157963194

Centisome position: 79.8

GC content: 49.81

Gene sequence:

>1032_bases
ATGATGTTTGATATTAAAGCTGTAAATACTGAATTTGATGATGAAATTCAGCAAAAAATAGACACTAAAACTAAGCCCCT
AGGCGCGCTGGGTGAGCTAGAACCGTTGGCTCTGCAAATAGCCCAAGTGCTGGGCAAAGATAAGCCACAGATCAGCAAGC
CAAAGATGATGGTATTTGCAGCCGACCATGGCATTGCACAGTCGGGGGTATCCATAGCCCCGAGTGAGGTGACCACACAG
ATGGTGGTTAACTTTATCAATGGTGGTGCGGCCATTAACGTGTTTACCCGTCAGGTTGGCTTCGACTTGGAAGTGATCGA
CTGCGGGATATTAAAGCCAATTGAAAACTTAGAAGGGGTGATCGACCAACGTTTAGGCTCAGGCACTGGCCCTATTCATA
AGCGTGCAGCCATGACGCTCGGCGCGGTGAAGCAAGGCTTTAAGATGGCGACCACGCGAGTGGAGATGCATCATCAAAAC
GGCTGTAACTTAATAGCCTTAGGCGAGATGGGGATTGGCAATACGTCGTCGGCAGCCGCGATAATGTCGGCCTTAACAGG
CTGTAAGGTGGAAGATTGTGTAGGCCGCGGCACCGGTATCGATGCGGCGACCTATAAGCGTAAGAAGATGCTCGTTGAGC
AAGCGCTGCTTGTACATCATAGCGAGCTTGATGACCCTATGCAGGTACTTGCCTGTGTCGGCGGCTTTGAGATAGTGCAG
ATGACGGGCGCAATGCTAGCCGCAGCTGAGCGTAACATGCTTGTGATTGTCGATGGCTTTATTGCCAGCGCGGCAGCATT
AGCGGCGGTAAAGATTAATCCAAATGTACGTGATTATATGATTTTCGCCCACCAGTCTGATGAGAAAGGCCATGTTCTGA
TGCTGGAGTTTCTGCAGGCTAGGCCACTATTAAAGCTTGGCATGAAACTCGGCGAAGGCACTGGCGCTGCATTAGCGTTA
CCCCTAATCCAAGCTGCGGCAAATTTTTATAACGAGATGGCCAGCTTCGAAGATGTCGGGATAGAGATTTAA

Upstream 100 bases:

>100_bases
GGGCAGTATTTTCTTTCTATTTATTTTAGGCAGTCGCAGCGGTAAACGTATTTAGCGAGCCACATTTATAACATCCTTAT
TGAGTGGTTGAGGGGAAACA

Downstream 100 bases:

>100_bases
GGACCGAAATAAACAAAGACGGTATAGGCTGAGACGGTGCAAGCTAAGACGGTACGAGCTGAGACGGTACGAGCTGAGAC
GGTACGAGCTGAAACGATGC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MMFDIKAVNTEFDDEIQQKIDTKTKPLGALGELEPLALQIAQVLGKDKPQISKPKMMVFAADHGIAQSGVSIAPSEVTTQ
MVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGSGTGPIHKRAAMTLGAVKQGFKMATTRVEMHHQN
GCNLIALGEMGIGNTSSAAAIMSALTGCKVEDCVGRGTGIDAATYKRKKMLVEQALLVHHSELDDPMQVLACVGGFEIVQ
MTGAMLAAAERNMLVIVDGFIASAAALAAVKINPNVRDYMIFAHQSDEKGHVLMLEFLQARPLLKLGMKLGEGTGAALAL
PLIQAAANFYNEMASFEDVGIEI

Sequences:

>Translated_343_residues
MMFDIKAVNTEFDDEIQQKIDTKTKPLGALGELEPLALQIAQVLGKDKPQISKPKMMVFAADHGIAQSGVSIAPSEVTTQ
MVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGSGTGPIHKRAAMTLGAVKQGFKMATTRVEMHHQN
GCNLIALGEMGIGNTSSAAAIMSALTGCKVEDCVGRGTGIDAATYKRKKMLVEQALLVHHSELDDPMQVLACVGGFEIVQ
MTGAMLAAAERNMLVIVDGFIASAAALAAVKINPNVRDYMIFAHQSDEKGHVLMLEFLQARPLLKLGMKLGEGTGAALAL
PLIQAAANFYNEMASFEDVGIEI
>Mature_343_residues
MMFDIKAVNTEFDDEIQQKIDTKTKPLGALGELEPLALQIAQVLGKDKPQISKPKMMVFAADHGIAQSGVSIAPSEVTTQ
MVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGSGTGPIHKRAAMTLGAVKQGFKMATTRVEMHHQN
GCNLIALGEMGIGNTSSAAAIMSALTGCKVEDCVGRGTGIDAATYKRKKMLVEQALLVHHSELDDPMQVLACVGGFEIVQ
MTGAMLAAAERNMLVIVDGFIASAAALAAVKINPNVRDYMIFAHQSDEKGHVLMLEFLQARPLLKLGMKLGEGTGAALAL
PLIQAAANFYNEMASFEDVGIEI

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=337, Percent_Identity=37.0919881305638, Blast_Score=215, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36565; Mature: 36565

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFDIKAVNTEFDDEIQQKIDTKTKPLGALGELEPLALQIAQVLGKDKPQISKPKMMVFA
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
ADHGIAQSGVSIAPSEVTTQMVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGV
ECCCCHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHCCCEEEECCCCCCHHHHHHHH
IDQRLGSGTGPIHKRAAMTLGAVKQGFKMATTRVEMHHQNGCNLIALGEMGIGNTSSAAA
HHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHEEEHHCCCCCEEEECCCCCCCCHHHHH
IMSALTGCKVEDCVGRGTGIDAATYKRKKMLVEQALLVHHSELDDPMQVLACVGGFEIVQ
HHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
MTGAMLAAAERNMLVIVDGFIASAAALAAVKINPNVRDYMIFAHQSDEKGHVLMLEFLQA
HHHHHHHHCCCCEEEEECCHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHH
RPLLKLGMKLGEGTGAALALPLIQAAANFYNEMASFEDVGIEI
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMFDIKAVNTEFDDEIQQKIDTKTKPLGALGELEPLALQIAQVLGKDKPQISKPKMMVFA
CEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEE
ADHGIAQSGVSIAPSEVTTQMVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGV
ECCCCHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHCCCEEEECCCCCCHHHHHHHH
IDQRLGSGTGPIHKRAAMTLGAVKQGFKMATTRVEMHHQNGCNLIALGEMGIGNTSSAAA
HHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHEEEHHCCCCCEEEECCCCCCCCHHHHH
IMSALTGCKVEDCVGRGTGIDAATYKRKKMLVEQALLVHHSELDDPMQVLACVGGFEIVQ
HHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
MTGAMLAAAERNMLVIVDGFIASAAALAAVKINPNVRDYMIFAHQSDEKGHVLMLEFLQA
HHHHHHHHCCCCEEEEECCHHHHHHHEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHH
RPLLKLGMKLGEGTGAALALPLIQAAANFYNEMASFEDVGIEI
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA