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The map label for this gene is leuE [H]

Identifier: 157963134

GI number: 157963134

Start: 4058662

End: 4059276

Strand: Reverse

Name: leuE [H]

Synonym: Spea_3318

Alternate gene names: 157963134

Gene position: 4059276-4058662 (Counterclockwise)

Preceding gene: 157963139

Following gene: 157963130

Centisome position: 78.45

GC content: 47.64

Gene sequence:

>615_bases
ATGACTATTAGTGCTTGGCTAGGCTTGTTAGCTATCTGCTGTTTAGGGGCCATGTCACCGGGGCCGAGTCTGGCTATGGT
AGTGAGACATACCTTAGGTGGAGGTAGAGGTAAAGGCATCATCTGCGCTTGGGCGCACTCAATTGGTATTGGTGTTTATG
CTTTGCTGACTTTATTAGGCTTAGCGGTATTGCTAAAGCAGGCGCCTATGGTGTTTAACGGTATTGCGATTATAGGTGCG
CTTTATCTTGCGTATATGGGCGTGCAGGCGCTGCGCTCAAAAGGCGGCATGTCAGATAAGCTAGCAGCTGGTGAGTCGAC
CGATGTCTTTACCGCGGCGCGTGATGGCTTAGCTATTTCACTGTTTAACCCCAAAATAATGTTGTTTTTTTTGGCGCTGT
TTAGCCAGTTTGTGCTGGTTGCAGACAATATGACGGGCAAGGTCTTGATTGTATTAACGCCGCTGATTGTTGATGGCCTT
TGGTACACGCTTATCGCCTTACTGCTTTCTCACTCGTCAGTGCTGCCTAAACTTAGAGAAAAAGCAGCCCTAATTGATAA
ACTATCGGGTGTAGTGCTTATTTTGTTGGCGGTGCGAGTAGTTGTGACGCTTTAG

Upstream 100 bases:

>100_bases
TTGTGATCTGCCTGCAGAGATCCTGTATATTGTGGCGATTACAAATAACTGAAACAGGTTAAGGCCAATACGTGAACAAA
AATAATAATCGAGGCAAGCA

Downstream 100 bases:

>100_bases
ATATTACAGATACAAAAAACGCCATCAATTTGATGGCGTTTTTTCGTTAAGCGTTTAATGCACTTGTAACCGATAGCGAT
TAAGAGGTGAATACCTGTAC

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTISAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGVYALLTLLGLAVLLKQAPMVFNGIAIIGA
LYLAYMGVQALRSKGGMSDKLAAGESTDVFTAARDGLAISLFNPKIMLFFLALFSQFVLVADNMTGKVLIVLTPLIVDGL
WYTLIALLLSHSSVLPKLREKAALIDKLSGVVLILLAVRVVVTL

Sequences:

>Translated_204_residues
MTISAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGVYALLTLLGLAVLLKQAPMVFNGIAIIGA
LYLAYMGVQALRSKGGMSDKLAAGESTDVFTAARDGLAISLFNPKIMLFFLALFSQFVLVADNMTGKVLIVLTPLIVDGL
WYTLIALLLSHSSVLPKLREKAALIDKLSGVVLILLAVRVVVTL
>Mature_203_residues
TISAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGVYALLTLLGLAVLLKQAPMVFNGIAIIGAL
YLAYMGVQALRSKGGMSDKLAAGESTDVFTAARDGLAISLFNPKIMLFFLALFSQFVLVADNMTGKVLIVLTPLIVDGLW
YTLIALLLSHSSVLPKLREKAALIDKLSGVVLILLAVRVVVTL

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786522, Length=177, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI48994978, Length=195, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21432; Mature: 21301

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGVYALLTLLG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVLLKQAPMVFNGIAIIGALYLAYMGVQALRSKGGMSDKLAAGESTDVFTAARDGLAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHCCCEEEE
LFNPKIMLFFLALFSQFVLVADNMTGKVLIVLTPLIVDGLWYTLIALLLSHSSVLPKLRE
EECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
KAALIDKLSGVVLILLAVRVVVTL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TISAWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGVYALLTLLG
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVLLKQAPMVFNGIAIIGALYLAYMGVQALRSKGGMSDKLAAGESTDVFTAARDGLAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHCCCEEEE
LFNPKIMLFFLALFSQFVLVADNMTGKVLIVLTPLIVDGLWYTLIALLLSHSSVLPKLRE
EECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
KAALIDKLSGVVLILLAVRVVVTL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA