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The map label for this gene is yfcG [H]

Identifier: 157962998

GI number: 157962998

Start: 3900419

End: 3901042

Strand: Reverse

Name: yfcG [H]

Synonym: Spea_3181

Alternate gene names: 157962998

Gene position: 3901042-3900419 (Counterclockwise)

Preceding gene: 157963004

Following gene: 157962993

Centisome position: 75.39

GC content: 49.52

Gene sequence:

>624_bases
ATGATTACACTATATGGGATCCCGCGTAGCCGCTCTTTGAGAGTGTCATGGACCTTAGAAGAGTTAGGACTCGACTGGCA
ATATCACTATATCAACTTTGCCAAGGGCGACAGTCGTGACCCCGCGTTTTTGGCCGTTAACCCTTGTGGCAAGGTTCCGG
CGCTGGTAGATGATGGTTTTGCATTAACTGAATCAGCAGCAATCGTACTTTATTTAGCTGAGAAATATGGTCAGGGTAAG
TTGCTGCCAAAGGTGGGGACTCATGAGTCGGCGCAGCATCATAAGTGGGTCAGCTTTATTATCAGTGAGCTTGAGCAGCC
GCTGTGGAGCATAGGAAAACATAAGTTTGCCCTGCCAGAGGAACAGCGTCTTCCTGCTATGCTATCGGTTGCTAAGTGGG
AGTTTGACAAGGCTGCGGCAATCGCCGAAAAGTGGTTACCTGAGAGTGATTTTTTACTTGGCGATGAGCTAAGTATTGCC
GATATATTGCTTGGGCATACCTTGCTGTGGGCGACACGATTTGAGCAAGATATTCCACCAAAACTGACCGCCTACCGCGA
TAGAATTACGGCTCGACCAGCCATGGCTAAGGGACTTGCTAAAGAAGAGGCGGGCGCCGCTTGA

Upstream 100 bases:

>100_bases
TGAAACCGATTTATTTTGAAACAATGTCACGGTTTCAATTGTTAACTCTTAGCGGTAGCTTAGGGGCTCACCCAATTGAT
GCAAATTAAGGAACAGTTAG

Downstream 100 bases:

>100_bases
GCTGACAAGGCACAGATTAACCCCTGCTCAAAGGAAAATTAAGCATAAAAAAAGCATCCACTATTTTAATAATAGAATGG
ATGCTTTTTTAATGCAGAAG

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MITLYGIPRSRSLRVSWTLEELGLDWQYHYINFAKGDSRDPAFLAVNPCGKVPALVDDGFALTESAAIVLYLAEKYGQGK
LLPKVGTHESAQHHKWVSFIISELEQPLWSIGKHKFALPEEQRLPAMLSVAKWEFDKAAAIAEKWLPESDFLLGDELSIA
DILLGHTLLWATRFEQDIPPKLTAYRDRITARPAMAKGLAKEEAGAA

Sequences:

>Translated_207_residues
MITLYGIPRSRSLRVSWTLEELGLDWQYHYINFAKGDSRDPAFLAVNPCGKVPALVDDGFALTESAAIVLYLAEKYGQGK
LLPKVGTHESAQHHKWVSFIISELEQPLWSIGKHKFALPEEQRLPAMLSVAKWEFDKAAAIAEKWLPESDFLLGDELSIA
DILLGHTLLWATRFEQDIPPKLTAYRDRITARPAMAKGLAKEEAGAA
>Mature_207_residues
MITLYGIPRSRSLRVSWTLEELGLDWQYHYINFAKGDSRDPAFLAVNPCGKVPALVDDGFALTESAAIVLYLAEKYGQGK
LLPKVGTHESAQHHKWVSFIISELEQPLWSIGKHKFALPEEQRLPAMLSVAKWEFDKAAAIAEKWLPESDFLLGDELSIA
DILLGHTLLWATRFEQDIPPKLTAYRDRITARPAMAKGLAKEEAGAA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=214, Percent_Identity=32.2429906542056, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081789, Length=172, Percent_Identity=31.9767441860465, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654975, Length=206, Percent_Identity=32.5242718446602, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85725204, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737923, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654992, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922526, Length=203, Percent_Identity=30.0492610837438, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922160, Length=169, Percent_Identity=31.9526627218935, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864598, Length=169, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922528, Length=197, Percent_Identity=29.9492385786802, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17864596, Length=168, Percent_Identity=27.9761904761905, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23142; Mature: 23142

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLYGIPRSRSLRVSWTLEELGLDWQYHYINFAKGDSRDPAFLAVNPCGKVPALVDDGF
CEEEEECCCCCEEEEEEEHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCEECCCC
ALTESAAIVLYLAEKYGQGKLLPKVGTHESAQHHKWVSFIISELEQPLWSIGKHKFALPE
EECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EQRLPAMLSVAKWEFDKAAAIAEKWLPESDFLLGDELSIADILLGHTLLWATRFEQDIPP
HHCCHHHHHHHHHCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCC
KLTAYRDRITARPAMAKGLAKEEAGAA
HHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITLYGIPRSRSLRVSWTLEELGLDWQYHYINFAKGDSRDPAFLAVNPCGKVPALVDDGF
CEEEEECCCCCEEEEEEEHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCEECCCC
ALTESAAIVLYLAEKYGQGKLLPKVGTHESAQHHKWVSFIISELEQPLWSIGKHKFALPE
EECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
EQRLPAMLSVAKWEFDKAAAIAEKWLPESDFLLGDELSIADILLGHTLLWATRFEQDIPP
HHCCHHHHHHHHHCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCC
KLTAYRDRITARPAMAKGLAKEEAGAA
HHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]