Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 157962986

GI number: 157962986

Start: 3882417

End: 3884279

Strand: Reverse

Name: hlyB [H]

Synonym: Spea_3169

Alternate gene names: 157962986

Gene position: 3884279-3882417 (Counterclockwise)

Preceding gene: 157962991

Following gene: 157962985

Centisome position: 75.06

GC content: 46.86

Gene sequence:

>1863_bases
ATGCTAATTCGTTACAAATTACTGTTAAGTGCAGGAGTGTCCATCACGGCGCTAGCCGCCATGTTTGGCCTTCAAGTTTA
TTTTACTCAAGTGCAAACGGAATTAGCACAAGCCTCGCAAGATATTTCGGAGCTCAAGAATGAAGTTTTAAGGTTACGTA
AAGATGAAAAGGATTTTCTAGCAAGGAAGGAGCTTAAGTATGTTGAGCAGCACGGGTCTGATAACCGAGAAGCTCAAGAT
AAGGTCGTTAAGCTGACCGCTGTGTTTGAAAAATATGAGATCCCAACAGCGAGTTTAAGTCTGTTTAGTCAAGAGCTCGG
CCGTTATGAATCAGCCTTTAGCAACGTAGTTAGCCTAAATAAGCAGATAGGTCTCACCCCTAAAGCGGGTTTATATGGCA
CCTTGCGAAGCGCAGTACATCAAGTAGAAAGTTTAGTTGAGCAATATGATGAACCACAATTGATGGTGCAGATGCTGCAA
CTTAGGCGCGCCGAGAAAGACTTTATGCTCAGACGTAGTGAAAGCTATGTGACAAAGTTTGATAAGAATCTCCAAACCTT
TATTAATACAGCGAACGCGTCCCAATTGGCAATACAAGCTAAGCAGCAGGTGTTGAGTAATATCCAGCAATATAATGCTG
ATTTCAAAGCCTTGGTGCAAAAAGAGAAACTGCTCGGTCTGACTATTTCTGAAGGCGAGCGAGGGAAATTACGCCAAGCG
GTTGCCAATACAGACAGTGCGCTTAAGCAGCTCGAATCTTTAGCCTTGAATGCCATCAGCGATAAAGAAAGTTCGGCGTT
TATCTTTGGCCTTGCGATTGCTGTCCTCATTGCCCTTGCGTTAGCAGTGACAACCTTGATGATTATCCGCAGTATTATCG
ATCCAGTTAAACGCATTACTGCTGTGATTACTCACATTGAGGCCAATAAAGATCTGTCGATGCGTTGTGATGCCAGCAGC
GACGACGAGCTTGGCCAAATAGCCAGACACTTTAACAGCATGGTAGAAAGCTTTCAGCAGCTTATTCATCAAGTGACGCA
ATCGGTTGAGACCATGAACCAGTCTTGCCAAGATCTCTCAAGTAATGTGGCACGCGCTTCACAAGGCGCTGAGAGTCAGC
TTAATGAAACCGATATGGTGGCTACAGCGATTACTGAGATGGGGGCGACCATTGATGAAATTGCTAAGAACACAGAACTT
GCCGCCAACAAGGCTAGCATGACTCACGACAACGCTCAGACGGGACAGGTTGGTGTGCAGCAGACGATTGAAAAAATCGA
GCTATTGGCACAACAGATCAATGAGTCTGCTGCAGTGGTGGGCGACCTTGAAAAAGACAGCGAAACTATTGGCAGTGTGC
TCGATGTTATTCGCGGTATTGCCGAGCAAACCAATTTACTGGCATTAAATGCGGCTATCGAAGCGGCAAGAGCGGGAGAG
CAGGGACGGGGCTTTGCGGTTGTCGCCGATGAGGTTCGAAGTCTTGCGATGCGAACTCAAGAGTCGACTGAGGAGATAGC
TGCAATCATTCAGACCTTACAGTCTCGAACCCACTCTATCGTAGCCCTGATGCAATCGAGTCGTGAGCAGGGCAACGAGA
GTGCTGAACAAGCCGCTTCTGCTGGGACTCTACTCGAGCAGATTAATGTTGACGTGACCAACATTATGGATATGAGCACT
CAGATTGCGGCTGCGATTGAAGAGCAAAGTATGGTTGCGGCCGAGGTTAATCAAAATGTGGTGGTGATCCGCGATATCGC
TCAGGAGACGGCCGATGTTGCTACGCAAAACTCCAGTGCCACAGAGGAAGTTCGTGAGCGTGCTGAGTTCCTGCAAGATG
CGGTAAGTAAATTTAAGGTTTAG

Upstream 100 bases:

>100_bases
ATGTACTAGGTAATCGGCCGATAGGGATAAATGACAGTCCGAGGAGGGTGCGAAAATGTGTTTTCCAAGGGAAATAAACC
GATAAAAAAAGAGATGTAAA

Downstream 100 bases:

>100_bases
ACATTCTTTTTTTGAATAGAAGCCTCGACTTAGCTCGGGGCTTTTTTATATGGATTGAATATACTTATACTGCCTGTATT
AAATTTCAGATATAAAAAAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFTQVQTELAQASQDISELKNEVLRLRKDEKDFLARKELKYVEQHGSDNREAQD
KVVKLTAVFEKYEIPTASLSLFSQELGRYESAFSNVVSLNKQIGLTPKAGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSESYVTKFDKNLQTFINTANASQLAIQAKQQVLSNIQQYNADFKALVQKEKLLGLTISEGERGKLRQA
VANTDSALKQLESLALNAISDKESSAFIFGLAIAVLIALALAVTTLMIIRSIIDPVKRITAVITHIEANKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQDLSSNVARASQGAESQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVGDLEKDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVALMQSSREQGNESAEQAASAGTLLEQINVDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETADVATQNSSATEEVRERAEFLQDAVSKFKV

Sequences:

>Translated_620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFTQVQTELAQASQDISELKNEVLRLRKDEKDFLARKELKYVEQHGSDNREAQD
KVVKLTAVFEKYEIPTASLSLFSQELGRYESAFSNVVSLNKQIGLTPKAGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSESYVTKFDKNLQTFINTANASQLAIQAKQQVLSNIQQYNADFKALVQKEKLLGLTISEGERGKLRQA
VANTDSALKQLESLALNAISDKESSAFIFGLAIAVLIALALAVTTLMIIRSIIDPVKRITAVITHIEANKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQDLSSNVARASQGAESQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVGDLEKDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVALMQSSREQGNESAEQAASAGTLLEQINVDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETADVATQNSSATEEVRERAEFLQDAVSKFKV
>Mature_620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFTQVQTELAQASQDISELKNEVLRLRKDEKDFLARKELKYVEQHGSDNREAQD
KVVKLTAVFEKYEIPTASLSLFSQELGRYESAFSNVVSLNKQIGLTPKAGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSESYVTKFDKNLQTFINTANASQLAIQAKQQVLSNIQQYNADFKALVQKEKLLGLTISEGERGKLRQA
VANTDSALKQLESLALNAISDKESSAFIFGLAIAVLIALALAVTTLMIIRSIIDPVKRITAVITHIEANKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQDLSSNVARASQGAESQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVGDLEKDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVALMQSSREQGNESAEQAASAGTLLEQINVDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETADVATQNSSATEEVRERAEFLQDAVSKFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=30.4225352112676, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=30.5031446540881, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788195, Length=333, Percent_Identity=30.3303303303303, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788194, Length=362, Percent_Identity=28.7292817679558, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=494, Percent_Identity=25.3036437246964, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67915; Mature: 67915

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRYKLLLSAGVSITALAAMFGLQVYFTQVQTELAQASQDISELKNEVLRLRKDEKDFL
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ARKELKYVEQHGSDNREAQDKVVKLTAVFEKYEIPTASLSLFSQELGRYESAFSNVVSLN
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQIGLTPKAGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQLRRAEKDFMLRRSESYVTKF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKNLQTFINTANASQLAIQAKQQVLSNIQQYNADFKALVQKEKLLGLTISEGERGKLRQA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCHHHHHH
VANTDSALKQLESLALNAISDKESSAFIFGLAIAVLIALALAVTTLMIIRSIIDPVKRIT
HHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVITHIEANKDLSMRCDASSDDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQDLS
HHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNVARASQGAESQLNETDMVATAITEMGATIDEIAKNTELAANKASMTHDNAQTGQVGVQ
HHHHHHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHCCHHHHHCHHHCCCCCCCCCHHHHH
QTIEKIELLAQQINESAAVVGDLEKDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVALMQSSREQGNESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGTLLEQINVDVTNIMDMSTQIAAAIEEQSMVAAEVNQNVVVIRDIAQETADVATQNSSA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCH
TEEVRERAEFLQDAVSKFKV
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIRYKLLLSAGVSITALAAMFGLQVYFTQVQTELAQASQDISELKNEVLRLRKDEKDFL
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ARKELKYVEQHGSDNREAQDKVVKLTAVFEKYEIPTASLSLFSQELGRYESAFSNVVSLN
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQIGLTPKAGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQLRRAEKDFMLRRSESYVTKF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKNLQTFINTANASQLAIQAKQQVLSNIQQYNADFKALVQKEKLLGLTISEGERGKLRQA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCCHHHHHH
VANTDSALKQLESLALNAISDKESSAFIFGLAIAVLIALALAVTTLMIIRSIIDPVKRIT
HHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVITHIEANKDLSMRCDASSDDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQDLS
HHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SNVARASQGAESQLNETDMVATAITEMGATIDEIAKNTELAANKASMTHDNAQTGQVGVQ
HHHHHHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHCCHHHHHCHHHCCCCCCCCCHHHHH
QTIEKIELLAQQINESAAVVGDLEKDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVALMQSSREQGNESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGTLLEQINVDVTNIMDMSTQIAAAIEEQSMVAAEVNQNVVVIRDIAQETADVATQNSSA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCH
TEEVRERAEFLQDAVSKFKV
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]