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The map label for this gene is sdsB [H]

Identifier: 157962991

GI number: 157962991

Start: 3887808

End: 3888710

Strand: Reverse

Name: sdsB [H]

Synonym: Spea_3174

Alternate gene names: 157962991

Gene position: 3888710-3887808 (Counterclockwise)

Preceding gene: 157962993

Following gene: 157962986

Centisome position: 75.15

GC content: 37.54

Gene sequence:

>903_bases
ATGGACTTACGGCATCTAAAACATTTTTCAGCATTAGCTGAATGTAGAAGTTTTAGTAAAGCGGCTGAAAAGCTAGAGAT
AACACAACCTTCTTTAACTCGTAGTATTCAGAAGATGGAACAAGATCTTGGAGTACAACTATTTACTCGAGACTCTAGAC
AGGTGAAATTAACCTATCACGGTGGGATAGTATTAAAGCATAGCGATAACATTCTAAATCGAGTGCATTTACTCGAGTCG
GATATAAGAGTAAATAGCGGAAAGCTAGCAGGGAAGCTGGTTATTGGTGGGGGGACTTTAACGTCGAGTCGTATATTGGG
TGAACTATTAAATGAGTTCGTTAAATATTCTCCATCGATTAGTGTAGAGCTGCGCGCTAGAGATGTTAGTGAGTTGCATC
AACTTCTTGCAAAGGGAGAGATCGATCTTTTTGTTGCGGAGACTAAAGTAACGCAGTTCGACCAAAGAGATGATCTTGAA
ATTATAAACTACTGTAACTCAGTAGGCGTATTTTGCTGTCGGCCAGGGCATCCGTTAGTGAGAGAGAAGAATCTATATAC
ACCTAGACTAAAAGATTTCCCTTTATCCCTGCCAAGAGCAACAACGAAAGAGGTTGAGGACTTATTCGGTGATCTTTTTG
ATATAGAGCGACCAGCTTTTTCAGGTTTGTTGAGATTCGAGTTGTTTAATTCAATTAGTTTACCTCTTTATAACACTAAT
ATGATCTGTCTATTACCAAAACTTGTTATTGATGAAGAATTAAAAGCGGGAAGTTTGGTATTGCTTGATGTTAAAGATAT
GCCACATATAAACGTAGACTTTGGTGCAGTATATTTAAAGTCGAAAAATTTAAATCCGGCTGCTAAAGAGTTTATTTCGT
TTGTTAAATCTTACGTGAACTAA

Upstream 100 bases:

>100_bases
GCATTTGACTAGTACTACCAGTTTATTGACTGCGATATTTTCTTCGGCTTGAGTAAAGTTTGGATTATTTATTGATTTAT
TGATTTATTGGATTAGGAGT

Downstream 100 bases:

>100_bases
TAATATTATTTATATATTATACATTATATGATGCAGCTGATTCTTTACTAGCTGCATCTGTTTAATCCCTGAAAAGTTAT
AATTTAATTACTTCAGTAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDLRHLKHFSALAECRSFSKAAEKLEITQPSLTRSIQKMEQDLGVQLFTRDSRQVKLTYHGGIVLKHSDNILNRVHLLES
DIRVNSGKLAGKLVIGGGTLTSSRILGELLNEFVKYSPSISVELRARDVSELHQLLAKGEIDLFVAETKVTQFDQRDDLE
IINYCNSVGVFCCRPGHPLVREKNLYTPRLKDFPLSLPRATTKEVEDLFGDLFDIERPAFSGLLRFELFNSISLPLYNTN
MICLLPKLVIDEELKAGSLVLLDVKDMPHINVDFGAVYLKSKNLNPAAKEFISFVKSYVN

Sequences:

>Translated_300_residues
MDLRHLKHFSALAECRSFSKAAEKLEITQPSLTRSIQKMEQDLGVQLFTRDSRQVKLTYHGGIVLKHSDNILNRVHLLES
DIRVNSGKLAGKLVIGGGTLTSSRILGELLNEFVKYSPSISVELRARDVSELHQLLAKGEIDLFVAETKVTQFDQRDDLE
IINYCNSVGVFCCRPGHPLVREKNLYTPRLKDFPLSLPRATTKEVEDLFGDLFDIERPAFSGLLRFELFNSISLPLYNTN
MICLLPKLVIDEELKAGSLVLLDVKDMPHINVDFGAVYLKSKNLNPAAKEFISFVKSYVN
>Mature_300_residues
MDLRHLKHFSALAECRSFSKAAEKLEITQPSLTRSIQKMEQDLGVQLFTRDSRQVKLTYHGGIVLKHSDNILNRVHLLES
DIRVNSGKLAGKLVIGGGTLTSSRILGELLNEFVKYSPSISVELRARDVSELHQLLAKGEIDLFVAETKVTQFDQRDDLE
IINYCNSVGVFCCRPGHPLVREKNLYTPRLKDFPLSLPRATTKEVEDLFGDLFDIERPAFSGLLRFELFNSISLPLYNTN
MICLLPKLVIDEELKAGSLVLLDVKDMPHINVDFGAVYLKSKNLNPAAKEFISFVKSYVN

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=267, Percent_Identity=25.4681647940075, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI157672245, Length=298, Percent_Identity=28.5234899328859, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693105, Length=300, Percent_Identity=26, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=33.5616438356164, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788887, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=148, Percent_Identity=35.1351351351351, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367136, Length=143, Percent_Identity=33.5664335664336, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790399, Length=148, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=193, Percent_Identity=24.3523316062176, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693193, Length=129, Percent_Identity=32.5581395348837, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788626, Length=153, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787530, Length=178, Percent_Identity=21.3483146067416, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33850; Mature: 33850

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRHLKHFSALAECRSFSKAAEKLEITQPSLTRSIQKMEQDLGVQLFTRDSRQVKLTYH
CCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEEE
GGIVLKHSDNILNRVHLLESDIRVNSGKLAGKLVIGGGTLTSSRILGELLNEFVKYSPSI
CCEEEEECCHHHHHHHHHHHCCEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
SVELRARDVSELHQLLAKGEIDLFVAETKVTQFDQRDDLEIINYCNSVGVFCCRPGHPLV
EEEEECCCHHHHHHHHHCCCEEEEEEECHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCC
REKNLYTPRLKDFPLSLPRATTKEVEDLFGDLFDIERPAFSGLLRFELFNSISLPLYNTN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCC
MICLLPKLVIDEELKAGSLVLLDVKDMPHINVDFGAVYLKSKNLNPAAKEFISFVKSYVN
HHEEHHHHHHHCCCCCCCEEEEEECCCCEEEECEEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLRHLKHFSALAECRSFSKAAEKLEITQPSLTRSIQKMEQDLGVQLFTRDSRQVKLTYH
CCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEEE
GGIVLKHSDNILNRVHLLESDIRVNSGKLAGKLVIGGGTLTSSRILGELLNEFVKYSPSI
CCEEEEECCHHHHHHHHHHHCCEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
SVELRARDVSELHQLLAKGEIDLFVAETKVTQFDQRDDLEIINYCNSVGVFCCRPGHPLV
EEEEECCCHHHHHHHHHCCCEEEEEEECHHHCCCCCCCHHHHHHHCCCCEEEECCCCCCC
REKNLYTPRLKDFPLSLPRATTKEVEDLFGDLFDIERPAFSGLLRFELFNSISLPLYNTN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCC
MICLLPKLVIDEELKAGSLVLLDVKDMPHINVDFGAVYLKSKNLNPAAKEFISFVKSYVN
HHEEHHHHHHHCCCCCCCEEEEEECCCCEEEECEEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]