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The map label for this gene is nlpI [H]

Identifier: 157962872

GI number: 157962872

Start: 3745676

End: 3746569

Strand: Reverse

Name: nlpI [H]

Synonym: Spea_3054

Alternate gene names: 157962872

Gene position: 3746569-3745676 (Counterclockwise)

Preceding gene: 157962873

Following gene: 157962871

Centisome position: 72.4

GC content: 44.52

Gene sequence:

>894_bases
ATGAATCAAAAGATGCGAACAGCCGTAATTATGCTTATGGCAAGTGTGAGTATGCTGCTGACAGGATGTGTGTCCACTCA
GTCCGATAGTGATCAACAAGCGTCGATTAGGGTTGCCCCCATTTCGCCTGATTATAAGTTAGAAATTACCTTAGCAAAGT
TAAATGAAATCCTAGCATCAGTCGAGTTAACGCCTGAGCAACGAGCACGTTTTCATTATGACCGCGGTGTGATTTACGAC
CGTGTTGGTTTGCGCATTCTGAGTCGAATCGATTTCCATCAGGCGCTAAAGCTGCAGCCTAATTTAGCCGATGCCTACAA
TTTTCTCGGGATCTATTACACTCAGGAAAGTGAGTTTGAAAGTGCCTATGAAGCATTTGATGCGGTATTGGAATTGTCCC
CTGAATACGACTATGCCTATCTGAACCGCGGAATTTCGCTTTATTATGGTGAGCGCATGGAGCTTGCTGTTTCAGATATG
ACCGCTTTTTATGACCGTGAGCCGTCAGATGGTTATAGAGTTCTTTGGCTCTATTTAGCCGAGCGGGAAGTCGATGAGCA
AGCCGCGCTGCTACAGCTGACGGAAAACCGCAAGAATTTGCAGGCGAATGCTTGGTCGACAGCGTTAGTTGATTTCTACT
TAGGCCAGAAGAGTAAGGAAGAGGTATTTAACCTCGCTAAAGAAGGGCTAAAACACCCTGATGAGTATGCCGAGCGTCTC
TGTGAAGCATATTTCTATATGGCTAAAATTGCGCAAAAACGAGGTGATAACGTTCAGGCGGCTAATTACTTTAGACTCGC
ATTGGCGACTAATATCTATGACTTCGTTGAACATAGATATGCAAGACTTGAGCTTGCGAGAACCAATGAAGCATTAAGAT
TGGCTACGAATTAA

Upstream 100 bases:

>100_bases
ATTAATCAACGATAAGTGGATTATTTTCAATTCCTTGATAGCAGTCGTGATTAGGGGTTGCTATGATTGGTGCTATTGGC
GAACTCAGAAGGTTAAATGG

Downstream 100 bases:

>100_bases
AGCGTTTTTATATCCTTGAAAGCCTCCTTTAGGAGGCTTTTTTATTGTCTGTATTTTACAAATGGTGGTGATGCTCATTT
TAGCCGCTTAGTGTGGTAGC

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNQKMRTAVIMLMASVSMLLTGCVSTQSDSDQQASIRVAPISPDYKLEITLAKLNEILASVELTPEQRARFHYDRGVIYD
RVGLRILSRIDFHQALKLQPNLADAYNFLGIYYTQESEFESAYEAFDAVLELSPEYDYAYLNRGISLYYGERMELAVSDM
TAFYDREPSDGYRVLWLYLAEREVDEQAALLQLTENRKNLQANAWSTALVDFYLGQKSKEEVFNLAKEGLKHPDEYAERL
CEAYFYMAKIAQKRGDNVQAANYFRLALATNIYDFVEHRYARLELARTNEALRLATN

Sequences:

>Translated_297_residues
MNQKMRTAVIMLMASVSMLLTGCVSTQSDSDQQASIRVAPISPDYKLEITLAKLNEILASVELTPEQRARFHYDRGVIYD
RVGLRILSRIDFHQALKLQPNLADAYNFLGIYYTQESEFESAYEAFDAVLELSPEYDYAYLNRGISLYYGERMELAVSDM
TAFYDREPSDGYRVLWLYLAEREVDEQAALLQLTENRKNLQANAWSTALVDFYLGQKSKEEVFNLAKEGLKHPDEYAERL
CEAYFYMAKIAQKRGDNVQAANYFRLALATNIYDFVEHRYARLELARTNEALRLATN
>Mature_297_residues
MNQKMRTAVIMLMASVSMLLTGCVSTQSDSDQQASIRVAPISPDYKLEITLAKLNEILASVELTPEQRARFHYDRGVIYD
RVGLRILSRIDFHQALKLQPNLADAYNFLGIYYTQESEFESAYEAFDAVLELSPEYDYAYLNRGISLYYGERMELAVSDM
TAFYDREPSDGYRVLWLYLAEREVDEQAALLQLTENRKNLQANAWSTALVDFYLGQKSKEEVFNLAKEGLKHPDEYAERL
CEAYFYMAKIAQKRGDNVQAANYFRLALATNIYDFVEHRYARLELARTNEALRLATN

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=282, Percent_Identity=42.9078014184397, Blast_Score=238, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 34262; Mature: 34262

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKMRTAVIMLMASVSMLLTGCVSTQSDSDQQASIRVAPISPDYKLEITLAKLNEILAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHH
VELTPEQRARFHYDRGVIYDRVGLRILSRIDFHQALKLQPNLADAYNFLGIYYTQESEFE
CCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEECCHHHH
SAYEAFDAVLELSPEYDYAYLNRGISLYYGERMELAVSDMTAFYDREPSDGYRVLWLYLA
HHHHHHHHHHHCCCCCCHHHHHCCEEEEECCCCEEHHHHHHHHHCCCCCCCEEEEEEEEE
EREVDEQAALLQLTENRKNLQANAWSTALVDFYLGQKSKEEVFNLAKEGLKHPDEYAERL
HHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
CEAYFYMAKIAQKRGDNVQAANYFRLALATNIYDFVEHRYARLELARTNEALRLATN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MNQKMRTAVIMLMASVSMLLTGCVSTQSDSDQQASIRVAPISPDYKLEITLAKLNEILAS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHH
VELTPEQRARFHYDRGVIYDRVGLRILSRIDFHQALKLQPNLADAYNFLGIYYTQESEFE
CCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEECCHHHH
SAYEAFDAVLELSPEYDYAYLNRGISLYYGERMELAVSDMTAFYDREPSDGYRVLWLYLA
HHHHHHHHHHHCCCCCCHHHHHCCEEEEECCCCEEHHHHHHHHHCCCCCCCEEEEEEEEE
EREVDEQAALLQLTENRKNLQANAWSTALVDFYLGQKSKEEVFNLAKEGLKHPDEYAERL
HHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHH
CEAYFYMAKIAQKRGDNVQAANYFRLALATNIYDFVEHRYARLELARTNEALRLATN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]