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The map label for this gene is dctS [H]

Identifier: 157962858

GI number: 157962858

Start: 3729023

End: 3730807

Strand: Reverse

Name: dctS [H]

Synonym: Spea_3040

Alternate gene names: 157962858

Gene position: 3730807-3729023 (Counterclockwise)

Preceding gene: 157962860

Following gene: 157962857

Centisome position: 72.1

GC content: 47.62

Gene sequence:

>1785_bases
TTGTCTCGGTTGTTGCTTTGTATTTGTGTGCTTTTGTTTTCATCGGTGGCTTGGGCTAAGCCGCAACAGTTCTATGTGGG
CGTACTAGCAAACTGGGGGCATCAGCAAGCAGTAGAGCGTTGGACACCTATGATGCAGTATCTCAATGAGCAGGTGCCTG
ATGCCGAGTTTCATGTGTACCCGGGAAACTTTGAGGCGCTAAATTTAGCCATGGAGTTGGGGCAAATTCAGTTCATCATC
ACCAACCCTGGACAATACCTATACCTCTCTAATCAATATCCCCTGTCTTGGCTTGCAACCATGCGTTCCATGCGCCACAG
GGGCACGACCTCGGCCATTGGCTCGGCGATCATTGTTAAGGCCGATAGTGAGTATCGTACTCTGTATGATTTAAAGGGAA
AAATTGTTGCGGCGAGTGATCCTCATGCGCTAGGTGGATACCAAGCAACAGTGGGTTTGATGCACAGCTTAGGCATGGAT
CCTGAAACCTACTTTGGCCAGACCAAGTTCCTAGGCTTTCCCCTTGACCCTTTGCTTTACCAAGTGCGAGACGGCAATGT
GGATGCGGCCATTACCCCTTTGTGCACTCTAGAAGACATGGTGGCGCGTGGATTAATTCAGCGCGGGGAGTATCGAGTGC
TCAATCCGAGCCGCCCCGAAGGAGTAGAGTGCCAGTGCAGTACCACCTTGTATCCCAACTGGTCATTTGCCGCGACTGAG
AGCGTCAGCACTGAGCTTAGTAAAGCGATCACCCAGGCTTTGCTTGATTTGAGCGCCGATAACCCGGCAGCCATTCAAGC
CCAGTTAAAGGGCTGGACATCGCCTATTAGTCAATTAGCGGTAATTAAACTATTTAAAGAGCTGCATGTTCAGTCTCCAG
ATAACAGCCGCTGGGATTCGGTTGAGCAATGGCTTAAGGATAATCGTCATTGGGGCATTTTATCTGTTTTAGTGTTTATT
ATTGCGACCTTGTATCACTTGTGGATTGAATACAGATTTCATCAAAAGAGCAGCTCCTTGATTGAGTCCGAGCGGCAATT
AAAGCAGCAAGCGGTCGCGCTTGAGCGCTTACAGAGTGCTTCTATTATTGGTGAGATTGGTGCAGGCTTGGCCCATGAGA
TAAACCAACCTATCGCGGCGATTACCAGTTATAGCGAAGGTGGCATCATGCGCTTACAAGGCCAGCAGCAAGCCGATGTT
GAGTCTTGTATCGCACTACTAGAAAAAATTCATAAACAATCGACTCGTGCGGGTGAGGTAGTACATCGAATTCGCGGCTT
GCTAAAGCGCCGAGAGGCGGTAATGGTCGATGTGAATATTCTTACCTTAGTCGAGGAGAGCATTTCACTATTAAGGCTTG
AGCTTGCAAGGCGCGAAATACAGATTAATACTCAGATTAAGGGCGAACCATTCTTTATTACCGCCGACAGGGTCGGCTTA
TTGCAGGTGCTGATAAATCTTATTAAAAATAGCTTAGATGCGATTGCTGACAGTGAGAATGCCCGTGTTGGTAAAATTAA
TATTGAGCTGGATTTTAAAGAGTATCAAGTGAATGTGCGTATTACCGATAATGGTCCCGGCTTAGCATTGGACTCAGACA
CGGTTATGGCAACCTTCTACACCACAAAGCTTGATGGTTTAGGCCTTGGGCTTGCCATCTGTAGAGAGGTGGTTAACGAC
CATAATGGACACTTTTTACTGAGTAATAGGGAGGATGATGCTTTAGGCTGCGTGGCAAAGGTTTACTTGAAGAAGCGTGG
TAGCGAAGCACCCATTGAAGTTTAG

Upstream 100 bases:

>100_bases
AAGTCCTATTTTACATTGAGTGAGTGCACAATACCTGAGTGTTCCCTCGTTACGGCTTTATTTGTAAATAGTGAATGACG
TTGATTCTAAGGAAATTTAA

Downstream 100 bases:

>100_bases
TTTAAACAGTGTTCATCGTATTTTAAGTACACTAATGTGCGGCTATTAAGCCGCACATTTTGTATCGAAAATATGCAGTA
ACTAGCAAAATTTTCAATTT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MSRLLLCICVLLFSSVAWAKPQQFYVGVLANWGHQQAVERWTPMMQYLNEQVPDAEFHVYPGNFEALNLAMELGQIQFII
TNPGQYLYLSNQYPLSWLATMRSMRHRGTTSAIGSAIIVKADSEYRTLYDLKGKIVAASDPHALGGYQATVGLMHSLGMD
PETYFGQTKFLGFPLDPLLYQVRDGNVDAAITPLCTLEDMVARGLIQRGEYRVLNPSRPEGVECQCSTTLYPNWSFAATE
SVSTELSKAITQALLDLSADNPAAIQAQLKGWTSPISQLAVIKLFKELHVQSPDNSRWDSVEQWLKDNRHWGILSVLVFI
IATLYHLWIEYRFHQKSSSLIESERQLKQQAVALERLQSASIIGEIGAGLAHEINQPIAAITSYSEGGIMRLQGQQQADV
ESCIALLEKIHKQSTRAGEVVHRIRGLLKRREAVMVDVNILTLVEESISLLRLELARREIQINTQIKGEPFFITADRVGL
LQVLINLIKNSLDAIADSENARVGKINIELDFKEYQVNVRITDNGPGLALDSDTVMATFYTTKLDGLGLGLAICREVVND
HNGHFLLSNREDDALGCVAKVYLKKRGSEAPIEV

Sequences:

>Translated_594_residues
MSRLLLCICVLLFSSVAWAKPQQFYVGVLANWGHQQAVERWTPMMQYLNEQVPDAEFHVYPGNFEALNLAMELGQIQFII
TNPGQYLYLSNQYPLSWLATMRSMRHRGTTSAIGSAIIVKADSEYRTLYDLKGKIVAASDPHALGGYQATVGLMHSLGMD
PETYFGQTKFLGFPLDPLLYQVRDGNVDAAITPLCTLEDMVARGLIQRGEYRVLNPSRPEGVECQCSTTLYPNWSFAATE
SVSTELSKAITQALLDLSADNPAAIQAQLKGWTSPISQLAVIKLFKELHVQSPDNSRWDSVEQWLKDNRHWGILSVLVFI
IATLYHLWIEYRFHQKSSSLIESERQLKQQAVALERLQSASIIGEIGAGLAHEINQPIAAITSYSEGGIMRLQGQQQADV
ESCIALLEKIHKQSTRAGEVVHRIRGLLKRREAVMVDVNILTLVEESISLLRLELARREIQINTQIKGEPFFITADRVGL
LQVLINLIKNSLDAIADSENARVGKINIELDFKEYQVNVRITDNGPGLALDSDTVMATFYTTKLDGLGLGLAICREVVND
HNGHFLLSNREDDALGCVAKVYLKKRGSEAPIEV
>Mature_593_residues
SRLLLCICVLLFSSVAWAKPQQFYVGVLANWGHQQAVERWTPMMQYLNEQVPDAEFHVYPGNFEALNLAMELGQIQFIIT
NPGQYLYLSNQYPLSWLATMRSMRHRGTTSAIGSAIIVKADSEYRTLYDLKGKIVAASDPHALGGYQATVGLMHSLGMDP
ETYFGQTKFLGFPLDPLLYQVRDGNVDAAITPLCTLEDMVARGLIQRGEYRVLNPSRPEGVECQCSTTLYPNWSFAATES
VSTELSKAITQALLDLSADNPAAIQAQLKGWTSPISQLAVIKLFKELHVQSPDNSRWDSVEQWLKDNRHWGILSVLVFII
ATLYHLWIEYRFHQKSSSLIESERQLKQQAVALERLQSASIIGEIGAGLAHEINQPIAAITSYSEGGIMRLQGQQQADVE
SCIALLEKIHKQSTRAGEVVHRIRGLLKRREAVMVDVNILTLVEESISLLRLELARREIQINTQIKGEPFFITADRVGLL
QVLINLIKNSLDAIADSENARVGKINIELDFKEYQVNVRITDNGPGLALDSDTVMATFYTTKLDGLGLGLAICREVVNDH
NGHFLLSNREDDALGCVAKVYLKKRGSEAPIEV

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=28.6274509803922, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=31.25, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66269; Mature: 66138

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLLCICVLLFSSVAWAKPQQFYVGVLANWGHQQAVERWTPMMQYLNEQVPDAEFHVY
CCHHHHHHHHHHHHHHCCCCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
PGNFEALNLAMELGQIQFIITNPGQYLYLSNQYPLSWLATMRSMRHRGTTSAIGSAIIVK
CCCHHHHHHHEECCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCHHHCCCEEEEE
ADSEYRTLYDLKGKIVAASDPHALGGYQATVGLMHSLGMDPETYFGQTKFLGFPLDPLLY
ECCCHHHHEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCEECCCCHHHHHE
QVRDGNVDAAITPLCTLEDMVARGLIQRGEYRVLNPSRPEGVECQCSTTLYPNWSFAATE
EEECCCCCEECCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHH
SVSTELSKAITQALLDLSADNPAAIQAQLKGWTSPISQLAVIKLFKELHVQSPDNSRWDS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VEQWLKDNRHWGILSVLVFIIATLYHLWIEYRFHQKSSSLIESERQLKQQAVALERLQSA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SIIGEIGAGLAHEINQPIAAITSYSEGGIMRLQGQQQADVESCIALLEKIHKQSTRAGEV
HHHHHHCCHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHH
VHRIRGLLKRREAVMVDVNILTLVEESISLLRLELARREIQINTQIKGEPFFITADRVGL
HHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEECCHHHH
LQVLINLIKNSLDAIADSENARVGKINIELDFKEYQVNVRITDNGPGLALDSDTVMATFY
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEEEECCCCCEEECCCCEEEEEE
TTKLDGLGLGLAICREVVNDHNGHFLLSNREDDALGCVAKVYLKKRGSEAPIEV
EEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SRLLLCICVLLFSSVAWAKPQQFYVGVLANWGHQQAVERWTPMMQYLNEQVPDAEFHVY
CHHHHHHHHHHHHHHCCCCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
PGNFEALNLAMELGQIQFIITNPGQYLYLSNQYPLSWLATMRSMRHRGTTSAIGSAIIVK
CCCHHHHHHHEECCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCHHHCCCEEEEE
ADSEYRTLYDLKGKIVAASDPHALGGYQATVGLMHSLGMDPETYFGQTKFLGFPLDPLLY
ECCCHHHHEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCEECCCCHHHHHE
QVRDGNVDAAITPLCTLEDMVARGLIQRGEYRVLNPSRPEGVECQCSTTLYPNWSFAATE
EEECCCCCEECCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCCCHHHH
SVSTELSKAITQALLDLSADNPAAIQAQLKGWTSPISQLAVIKLFKELHVQSPDNSRWDS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VEQWLKDNRHWGILSVLVFIIATLYHLWIEYRFHQKSSSLIESERQLKQQAVALERLQSA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SIIGEIGAGLAHEINQPIAAITSYSEGGIMRLQGQQQADVESCIALLEKIHKQSTRAGEV
HHHHHHCCHHHHHHCCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHH
VHRIRGLLKRREAVMVDVNILTLVEESISLLRLELARREIQINTQIKGEPFFITADRVGL
HHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEECCHHHH
LQVLINLIKNSLDAIADSENARVGKINIELDFKEYQVNVRITDNGPGLALDSDTVMATFY
HHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEEEEEEEECCCCCEEECCCCEEEEEE
TTKLDGLGLGLAICREVVNDHNGHFLLSNREDDALGCVAKVYLKKRGSEAPIEV
EEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]