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The map label for this gene is 157962756

Identifier: 157962756

GI number: 157962756

Start: 3599380

End: 3600759

Strand: Reverse

Name: 157962756

Synonym: Spea_2938

Alternate gene names: NA

Gene position: 3600759-3599380 (Counterclockwise)

Preceding gene: 157962757

Following gene: 157962750

Centisome position: 69.59

GC content: 43.99

Gene sequence:

>1380_bases
TTGCACACCATCGAGCAGTTAAAATCGGGGCAGTTAAAAGGAATTAAACGCGTACAGATTGCTGAAGGCTTAACGCAGTT
TCCACAAGAAATTTTCTCTCTAGCCGATAGCTTGGAAGTACTGGATCTATCAGGCAATAAACTGAGTGAGTTACCAGATA
ATCTAAGTGATTTGCATCAGTTAAAGATCCTGTTCCTCACCGAAAATTGTTTTGAATCTGTTCCGTTAGTGCTTGCACAG
TGCCCTAAGCTTGAAATGATCAGCTTTAAGTCGAACAACTTAACGCAACTTCCTGAAAAAGCACTGCCCGATAATACCCG
CTGGTTAATTCTAACGGATAATAAGCTTGCCTCTTTGCCTGAAGATATGGGCAGGTTGCATCGACTGCAAAAGCTTGCAT
TAGCGGGTAATAAGCTCACTTGCTTACCCGAGGGTATGGCTAAGTGTACTAACTTAGAATTAGCTCGCTTATCGGCAAAT
GACTTTGACTCATTGCCAGATTGGTTATTTCAGCTACCACGCCTGAGCTGGTTAGCAGTTGATGGCAGTCCACTTATATC
GCAGCAAGACTCAACCGCAGAAGCTGGTGTAGAGCTTATCTCTATGCCAAGAGTGGGTCTTGACGATATCGAGCTGCAAG
AAGTCATTGGTCAAGGTGCATCGGGTGTGATTTACCGCGCTAAATGGGTTAACCAACCTCTTGAGTTGATGACAACGCCT
GTCTATATTGCAGTCAAAATATTTAAGGGGGAGGTCACCAGTGACGGTTACCCAAAAGATGAATTGGCTAATTGTTTGCA
AGCTGGGCAACACAGTAATCTGATCAAGGTTGTTGCAGAGCTTAAGCAAGCGGATAAAACGGGACTCGTGATGGAGCTTA
TTCCGAGTCACTACCAAAACTTAGGTCTGCCACCGTCACTAGAGACTTGTACTCGAGATACCTTCGCCAATGAGTCTGTG
TTTGAGCTTAAAGCAATACTGCTTATCTTGAAACAGATGGCGTCGGGTCTTGCTCATCTACATCAAAATCAAATCAGTCA
TGGCGATATCTACGCTCATAACACCATGTTCAATACCCATGCTGAGATCCTATTTGGCGACTTTGGTGCTGCAACCAACT
TAAGCCAGTTACCTATGCAGCAAAGAGAGGCTATGGAGGCAATAGAAGTGCGAGCTTTAGGTTGCTTAATAGAGGATTTA
GTCGAGCATTGTCTGCAAAATCCAATGCAAGTAAACCAAGTGATGCTTACTGAGTTATTGCAGTTGAAAGAGGCATGTTT
ACAGCCAAGTTTGGGATTACGCCCACGCTTTAAAGAGGTACATGTGCTGTTACAGCAAATGAGTGAGCAGCTCGATTCTG
AAGCTTGTTTAAGTGCTTAG

Upstream 100 bases:

>100_bases
GTTGGATGATTAATCTCTAACTTTTGAATTTTCCGCGACGATAGCCTTTGAATCGTATAATATTGCGCGCTGTTTTTCAT
CGGCATTTAGGATTAAGATT

Downstream 100 bases:

>100_bases
AGTTAGTGCTTAGAGTTAGCGCTTAGAGATTGCTTAGCATTAAACATAAAAACGCCGTCAATTGACGGCGTTTTTGTTTG
AACAGTTTGATAGATTTGCT

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: Leucine-Rich Repeat-Containing Protein; Protein Kinase; Cytoplasmic Membrane Protein; Leucine-Rich Repeat Protein; Leucine-Rich Repeat-Containing Protein Kinase; Ras Family; Miro-Like Protein; Outer Membrane Protein; Kinase; Phosphoprotein Phosphatase; Serine/Threonine-Protein Kinase-Like Domain Protein; Miro Domain Protein; Miro Domain-Containing Protein; Serine/Threonine-Protein Kinase-Like Domain; Leucine Rich Repeat Domain-Containing Protein; Protein Kinase Domain-Containing Protein; Leucine Rich Repeat Domain Protein; Leucine-Rich Repeat-Containing Protein Typical Subtype; Outermembrane Protein; Protein KinaseLeucine-Rich Repeat Protein; Lipoprotein

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MHTIEQLKSGQLKGIKRVQIAEGLTQFPQEIFSLADSLEVLDLSGNKLSELPDNLSDLHQLKILFLTENCFESVPLVLAQ
CPKLEMISFKSNNLTQLPEKALPDNTRWLILTDNKLASLPEDMGRLHRLQKLALAGNKLTCLPEGMAKCTNLELARLSAN
DFDSLPDWLFQLPRLSWLAVDGSPLISQQDSTAEAGVELISMPRVGLDDIELQEVIGQGASGVIYRAKWVNQPLELMTTP
VYIAVKIFKGEVTSDGYPKDELANCLQAGQHSNLIKVVAELKQADKTGLVMELIPSHYQNLGLPPSLETCTRDTFANESV
FELKAILLILKQMASGLAHLHQNQISHGDIYAHNTMFNTHAEILFGDFGAATNLSQLPMQQREAMEAIEVRALGCLIEDL
VEHCLQNPMQVNQVMLTELLQLKEACLQPSLGLRPRFKEVHVLLQQMSEQLDSEACLSA

Sequences:

>Translated_459_residues
MHTIEQLKSGQLKGIKRVQIAEGLTQFPQEIFSLADSLEVLDLSGNKLSELPDNLSDLHQLKILFLTENCFESVPLVLAQ
CPKLEMISFKSNNLTQLPEKALPDNTRWLILTDNKLASLPEDMGRLHRLQKLALAGNKLTCLPEGMAKCTNLELARLSAN
DFDSLPDWLFQLPRLSWLAVDGSPLISQQDSTAEAGVELISMPRVGLDDIELQEVIGQGASGVIYRAKWVNQPLELMTTP
VYIAVKIFKGEVTSDGYPKDELANCLQAGQHSNLIKVVAELKQADKTGLVMELIPSHYQNLGLPPSLETCTRDTFANESV
FELKAILLILKQMASGLAHLHQNQISHGDIYAHNTMFNTHAEILFGDFGAATNLSQLPMQQREAMEAIEVRALGCLIEDL
VEHCLQNPMQVNQVMLTELLQLKEACLQPSLGLRPRFKEVHVLLQQMSEQLDSEACLSA
>Mature_459_residues
MHTIEQLKSGQLKGIKRVQIAEGLTQFPQEIFSLADSLEVLDLSGNKLSELPDNLSDLHQLKILFLTENCFESVPLVLAQ
CPKLEMISFKSNNLTQLPEKALPDNTRWLILTDNKLASLPEDMGRLHRLQKLALAGNKLTCLPEGMAKCTNLELARLSAN
DFDSLPDWLFQLPRLSWLAVDGSPLISQQDSTAEAGVELISMPRVGLDDIELQEVIGQGASGVIYRAKWVNQPLELMTTP
VYIAVKIFKGEVTSDGYPKDELANCLQAGQHSNLIKVVAELKQADKTGLVMELIPSHYQNLGLPPSLETCTRDTFANESV
FELKAILLILKQMASGLAHLHQNQISHGDIYAHNTMFNTHAEILFGDFGAATNLSQLPMQQREAMEAIEVRALGCLIEDL
VEHCLQNPMQVNQVMLTELLQLKEACLQPSLGLRPRFKEVHVLLQQMSEQLDSEACLSA

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI95113664, Length=164, Percent_Identity=34.1463414634146, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI110825984, Length=202, Percent_Identity=29.7029702970297, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI8923909, Length=187, Percent_Identity=32.0855614973262, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI55770895, Length=187, Percent_Identity=32.0855614973262, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI154091020, Length=150, Percent_Identity=30.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI6912638, Length=155, Percent_Identity=36.1290322580645, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI256017180, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI34577083, Length=142, Percent_Identity=35.9154929577465, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI16904383, Length=186, Percent_Identity=31.1827956989247, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33859670, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61742786, Length=270, Percent_Identity=30, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61742784, Length=270, Percent_Identity=30, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI256017174, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI197333706, Length=165, Percent_Identity=32.1212121212121, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI34222199, Length=165, Percent_Identity=32.1212121212121, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI122937315, Length=162, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI187829877, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI62241040, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI187829871, Length=165, Percent_Identity=30.9090909090909, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI45827729, Length=159, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI45827731, Length=159, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI238908508, Length=164, Percent_Identity=28.6585365853659, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI153792305, Length=143, Percent_Identity=34.965034965035, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI21389431, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI157743290, Length=211, Percent_Identity=30.3317535545024, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI41281398, Length=162, Percent_Identity=31.4814814814815, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI194394161, Length=152, Percent_Identity=30.9210526315789, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI19923729, Length=163, Percent_Identity=30.6748466257669, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI40217803, Length=169, Percent_Identity=34.9112426035503, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI190014581, Length=159, Percent_Identity=32.7044025157233, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71981160, Length=179, Percent_Identity=31.2849162011173, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71981152, Length=179, Percent_Identity=31.2849162011173, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71998904, Length=173, Percent_Identity=34.1040462427746, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71998900, Length=173, Percent_Identity=34.1040462427746, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537883, Length=173, Percent_Identity=34.1040462427746, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552452, Length=155, Percent_Identity=34.8387096774194, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71991525, Length=174, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71991531, Length=174, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550406, Length=149, Percent_Identity=30.8724832214765, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324929, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221379725, Length=173, Percent_Identity=29.4797687861272, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221379722, Length=173, Percent_Identity=29.4797687861272, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362653, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281362651, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24650334, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24650332, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI62472958, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24650336, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281362657, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007092, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281362655, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24650330, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17933612, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18858105, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922294, Length=159, Percent_Identity=30.8176100628931, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50961; Mature: 50961

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIEQLKSGQLKGIKRVQIAEGLTQFPQEIFSLADSLEVLDLSGNKLSELPDNLSDLHQ
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCHHHHHH
LKILFLTENCFESVPLVLAQCPKLEMISFKSNNLTQLPEKALPDNTRWLILTDNKLASLP
HHHHEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCEEEEEECCHHHHCH
EDMGRLHRLQKLALAGNKLTCLPEGMAKCTNLELARLSANDFDSLPDWLFQLPRLSWLAV
HHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCHHEECCCCCCCHHHHHHHHCCCCEEEEE
DGSPLISQQDSTAEAGVELISMPRVGLDDIELQEVIGQGASGVIYRAKWVNQPLELMTTP
CCCCCCCCCCCHHHHCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCHHHHCCC
VYIAVKIFKGEVTSDGYPKDELANCLQAGQHSNLIKVVAELKQADKTGLVMELIPSHYQN
EEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGLPPSLETCTRDTFANESVFELKAILLILKQMASGLAHLHQNQISHGDIYAHNTMFNTH
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEECCC
AEILFGDFGAATNLSQLPMQQREAMEAIEVRALGCLIEDLVEHCLQNPMQVNQVMLTELL
HHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QLKEACLQPSLGLRPRFKEVHVLLQQMSEQLDSEACLSA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure
MHTIEQLKSGQLKGIKRVQIAEGLTQFPQEIFSLADSLEVLDLSGNKLSELPDNLSDLHQ
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCHHHHHH
LKILFLTENCFESVPLVLAQCPKLEMISFKSNNLTQLPEKALPDNTRWLILTDNKLASLP
HHHHEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCCCCEEEEEECCHHHHCH
EDMGRLHRLQKLALAGNKLTCLPEGMAKCTNLELARLSANDFDSLPDWLFQLPRLSWLAV
HHHHHHHHHHHHHHCCCCEEECCHHHHHHCCCHHEECCCCCCCHHHHHHHHCCCCEEEEE
DGSPLISQQDSTAEAGVELISMPRVGLDDIELQEVIGQGASGVIYRAKWVNQPLELMTTP
CCCCCCCCCCCHHHHCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCHHHHCCC
VYIAVKIFKGEVTSDGYPKDELANCLQAGQHSNLIKVVAELKQADKTGLVMELIPSHYQN
EEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGLPPSLETCTRDTFANESVFELKAILLILKQMASGLAHLHQNQISHGDIYAHNTMFNTH
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEECCC
AEILFGDFGAATNLSQLPMQQREAMEAIEVRALGCLIEDLVEHCLQNPMQVNQVMLTELL
HHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QLKEACLQPSLGLRPRFKEVHVLLQQMSEQLDSEACLSA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA