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The map label for this gene is acyII [H]

Identifier: 157962732

GI number: 157962732

Start: 3565620

End: 3567932

Strand: Reverse

Name: acyII [H]

Synonym: Spea_2914

Alternate gene names: 157962732

Gene position: 3567932-3565620 (Counterclockwise)

Preceding gene: 157962737

Following gene: 157962724

Centisome position: 68.95

GC content: 47.47

Gene sequence:

>2313_bases
ATGCATAAAACAATAAAAATAGCACTCATTGGAACCTCGTCAGTTGCAGCGGCCGTTGCTGGTGGTTTGTACCTAACTTT
GTCTTTGAGTTTACCCAAGCTCGATACCGATGTAATCAGCGAAAATATTAAGCAGCCAGTGAGCCTAGCGCGAGATAGGC
TAGGTACTGCAATTATTCACGCTAGTGACCGACAGGATGCGGCCTATGGTCTAGGTTATGCTCATGGACAGGACAGATTC
TTTCAAATGGATCTGCTGCGCCGCAACTCCGCCGGTGAACTCGCGGAGATCTTCGGTGAAAAAGCTTTAGATTTAGATAA
GCGTCGTCGTTTTCATCAGTTACGTAAACGTGCAGAGCTTATTGTCACAAAGTTAGATGCAACGCATTTGAAGGTGCTCA
CCACCTACGCTCAAGGGGTGAATGATGCGCTTGCTGCTCAGAGTCTCTCTTCATTTGAGTATATTGTAACAGGGGCAAAT
CCAAAACCTTGGGTACCAGCAGACAGCTTGCTGGTGATCTACAGCATGTATCTCGACCTGCAGGGCAACACCATTAAGCG
CGACTTAGCGCTTACTCAAATTCAAGATCTATTTGGCGAGAAGATGGTCGATTTTCTTATTCAGCCGAGTCAATATCAAG
CGGCGCTGGATGGCAGTCAACTTGCGTTAACAGCAATGCCGATCCCACCGCTCTCTAATAACATGCTTGCACAGGCCAAG
TTCCAACAGATTGCTGAGCCACTCGATATTGGCAGTAATAACTGGGCGGTCACCGGAGAGTTAACCGCTAACGGTAAGGC
TATGTTATCCGATGATATGCATCTGTCTTTTGCCGTGCCGATTATCTGGTATCGGGCTCAATTGAATTATCAAAAAGAGG
GCGTTGAGCAACAGGTGACCGGAGTCTCACTACCCGGCGCGCCAGCGATTGTTGTGGGCAGTAATGGCAAGGTGGCTTGG
GGCTTCACCAATGCTTATATCGATACCGCAGATTGGATAGCAATTGATGAGCAAACACCTATCTATTTTGAACATGAAAC
CATTGCCTTACCCGATTCAGAGGTAAGCTATACCATCGAGATGTCGCCTTTCGGGCCAGTCAAAGAGGTTGGTGATAAAA
GGTATGCGCTATCTTGGGTTGGCCATAGCGATTATGCGGTGGATATGCAGTTAATTGAGCTAGATAGCATCGGCAATGTT
GAGCAAGGCATTGAGGTTGCCGAGAAAATGGGGATCCCGGTGCAAAATATGCTGTTAGTTGACAGTAACGGCAGTGTGGC
TTGGAAACCGGCGGGGGCATATCCATCGAGGACGAATCCCAGTAATGTTGCCATGGCAACAACAGATTTTCAAAGTGTAA
ATTGGCAACAAGATAAAGCAGTATTACCGCAGGTTATCAATCCTGAAAATAACCGACTATGGACCGGAAACTCTCGTGTG
GTATCGGTTGAACAGCAACAGCTGCTAGGAGATGGTGGTTATGCCCTTGGGGCTCGCAGTATGCAGATCCGAGACAGACT
GTTTGAGTCGGACCGTTTCTCGGTCGAGGATTTTTATCAGTTACAGCTAGATAATGAAGCGCGTTTTTTGATGGACTGGC
AGCAGTTACTGCTTAATCAATTAAGCCAACAACCTGAACGTTTTGCTAAAGATATTGAGTACTTAACATCATGGCAGGCA
TGTGCTTGCAGTGATTCTGTCGGTTATACCTTAGTTCGCCACTTTAGAACGCGAGTTATCGATACCACCTTTGCGCCAAT
TGAAACTGAGCTTGCTAAAAGTGAGCTCAGTCTCTCAGCTATAAAGCGCTATTTAGAGCCGGGAATATGGCAGCTGATTA
ATGCGCAAGAGCCTAGCTGGTTACCTCAGGATGAGCACAGCTGGTCAGGCTATCTGCTACAAATTTACCTAAACGTTAAA
GAGGCGAGTTTAGCTAAATACAGTGACAATAATGACATGGCAGATTTGGCTTGGGGCAAGGTGAATCAACTTAAGATCCA
GCATCCGTTTTCTAAGCAGATCCCGGCGCTGAGTAGCTTGCTGGATATGCCGGTAGTTGAAGGCTTTGGTGACAGCTTTA
TGCCCGCAGTGCAAGGTGCATCGTTTGGTGCATCCCAGCGCTTTATTGTACAGCCGGGTGATGAAGTCAATGCCATAATG
ACGATACCGGGTGGCCAGTCAGGGCATCCGCTATCCGCTTTTTATCGCTCCGGTTTCGATGACTATGTGACACAGCAAAG
TACACCGTTACTCCCGGGAGAGGCGATTCATCGACTGGAGATCACCCCTGAAGTGAAGCGGGGTTATGAGTAA

Upstream 100 bases:

>100_bases
ATTTGTTTGAAATAAAGATAAAATTCAAATGACTGTTTAACAATTTTGTAACCCAGTTTATGATGCATTAGATATATTTA
GCGCAGGGACAGCAGAAGCG

Downstream 100 bases:

>100_bases
CTATTTAGCTGATATGTTCGAGATAAAGCGCCTTTGTCTAAGGAGGGCTTTATCTCGTGCTTGCTAAGGCTGAACACTAC
CATCTGAATTATAGAAAGCA

Product: penicillin amidase

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MHKTIKIALIGTSSVAAAVAGGLYLTLSLSLPKLDTDVISENIKQPVSLARDRLGTAIIHASDRQDAAYGLGYAHGQDRF
FQMDLLRRNSAGELAEIFGEKALDLDKRRRFHQLRKRAELIVTKLDATHLKVLTTYAQGVNDALAAQSLSSFEYIVTGAN
PKPWVPADSLLVIYSMYLDLQGNTIKRDLALTQIQDLFGEKMVDFLIQPSQYQAALDGSQLALTAMPIPPLSNNMLAQAK
FQQIAEPLDIGSNNWAVTGELTANGKAMLSDDMHLSFAVPIIWYRAQLNYQKEGVEQQVTGVSLPGAPAIVVGSNGKVAW
GFTNAYIDTADWIAIDEQTPIYFEHETIALPDSEVSYTIEMSPFGPVKEVGDKRYALSWVGHSDYAVDMQLIELDSIGNV
EQGIEVAEKMGIPVQNMLLVDSNGSVAWKPAGAYPSRTNPSNVAMATTDFQSVNWQQDKAVLPQVINPENNRLWTGNSRV
VSVEQQQLLGDGGYALGARSMQIRDRLFESDRFSVEDFYQLQLDNEARFLMDWQQLLLNQLSQQPERFAKDIEYLTSWQA
CACSDSVGYTLVRHFRTRVIDTTFAPIETELAKSELSLSAIKRYLEPGIWQLINAQEPSWLPQDEHSWSGYLLQIYLNVK
EASLAKYSDNNDMADLAWGKVNQLKIQHPFSKQIPALSSLLDMPVVEGFGDSFMPAVQGASFGASQRFIVQPGDEVNAIM
TIPGGQSGHPLSAFYRSGFDDYVTQQSTPLLPGEAIHRLEITPEVKRGYE

Sequences:

>Translated_770_residues
MHKTIKIALIGTSSVAAAVAGGLYLTLSLSLPKLDTDVISENIKQPVSLARDRLGTAIIHASDRQDAAYGLGYAHGQDRF
FQMDLLRRNSAGELAEIFGEKALDLDKRRRFHQLRKRAELIVTKLDATHLKVLTTYAQGVNDALAAQSLSSFEYIVTGAN
PKPWVPADSLLVIYSMYLDLQGNTIKRDLALTQIQDLFGEKMVDFLIQPSQYQAALDGSQLALTAMPIPPLSNNMLAQAK
FQQIAEPLDIGSNNWAVTGELTANGKAMLSDDMHLSFAVPIIWYRAQLNYQKEGVEQQVTGVSLPGAPAIVVGSNGKVAW
GFTNAYIDTADWIAIDEQTPIYFEHETIALPDSEVSYTIEMSPFGPVKEVGDKRYALSWVGHSDYAVDMQLIELDSIGNV
EQGIEVAEKMGIPVQNMLLVDSNGSVAWKPAGAYPSRTNPSNVAMATTDFQSVNWQQDKAVLPQVINPENNRLWTGNSRV
VSVEQQQLLGDGGYALGARSMQIRDRLFESDRFSVEDFYQLQLDNEARFLMDWQQLLLNQLSQQPERFAKDIEYLTSWQA
CACSDSVGYTLVRHFRTRVIDTTFAPIETELAKSELSLSAIKRYLEPGIWQLINAQEPSWLPQDEHSWSGYLLQIYLNVK
EASLAKYSDNNDMADLAWGKVNQLKIQHPFSKQIPALSSLLDMPVVEGFGDSFMPAVQGASFGASQRFIVQPGDEVNAIM
TIPGGQSGHPLSAFYRSGFDDYVTQQSTPLLPGEAIHRLEITPEVKRGYE
>Mature_770_residues
MHKTIKIALIGTSSVAAAVAGGLYLTLSLSLPKLDTDVISENIKQPVSLARDRLGTAIIHASDRQDAAYGLGYAHGQDRF
FQMDLLRRNSAGELAEIFGEKALDLDKRRRFHQLRKRAELIVTKLDATHLKVLTTYAQGVNDALAAQSLSSFEYIVTGAN
PKPWVPADSLLVIYSMYLDLQGNTIKRDLALTQIQDLFGEKMVDFLIQPSQYQAALDGSQLALTAMPIPPLSNNMLAQAK
FQQIAEPLDIGSNNWAVTGELTANGKAMLSDDMHLSFAVPIIWYRAQLNYQKEGVEQQVTGVSLPGAPAIVVGSNGKVAW
GFTNAYIDTADWIAIDEQTPIYFEHETIALPDSEVSYTIEMSPFGPVKEVGDKRYALSWVGHSDYAVDMQLIELDSIGNV
EQGIEVAEKMGIPVQNMLLVDSNGSVAWKPAGAYPSRTNPSNVAMATTDFQSVNWQQDKAVLPQVINPENNRLWTGNSRV
VSVEQQQLLGDGGYALGARSMQIRDRLFESDRFSVEDFYQLQLDNEARFLMDWQQLLLNQLSQQPERFAKDIEYLTSWQA
CACSDSVGYTLVRHFRTRVIDTTFAPIETELAKSELSLSAIKRYLEPGIWQLINAQEPSWLPQDEHSWSGYLLQIYLNVK
EASLAKYSDNNDMADLAWGKVNQLKIQHPFSKQIPALSSLLDMPVVEGFGDSFMPAVQGASFGASQRFIVQPGDEVNAIM
TIPGGQSGHPLSAFYRSGFDDYVTQQSTPLLPGEAIHRLEITPEVKRGYE

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 85373; Mature: 85373

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKTIKIALIGTSSVAAAVAGGLYLTLSLSLPKLDTDVISENIKQPVSLARDRLGTAIIH
CCCEEEEEEEECCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
ASDRQDAAYGLGYAHGQDRFFQMDLLRRNSAGELAEIFGEKALDLDKRRRFHQLRKRAEL
ECCCCCCHHCCCEECCCCCEEEEHHHHCCCCCHHHHHHCHHHCCHHHHHHHHHHHHHHHH
IVTKLDATHLKVLTTYAQGVNDALAAQSLSSFEYIVTGANPKPWVPADSLLVIYSMYLDL
EEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHEEEHHEEC
QGNTIKRDLALTQIQDLFGEKMVDFLIQPSQYQAALDGSQLALTAMPIPPLSNNMLAQAK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
FQQIAEPLDIGSNNWAVTGELTANGKAMLSDDMHLSFAVPIIWYRAQLNYQKEGVEQQVT
HHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCEEEEEEEEEEEEEECCCHHHCHHHHHC
GVSLPGAPAIVVGSNGKVAWGFTNAYIDTADWIAIDEQTPIYFEHETIALPDSEVSYTIE
CCCCCCCCEEEECCCCEEEEEEECCEECCCCEEEECCCCCEEEECCEEECCCCCEEEEEE
MSPFGPVKEVGDKRYALSWVGHSDYAVDMQLIELDSIGNVEQGIEVAEKMGIPVQNMLLV
ECCCCCHHHHCCCEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEE
DSNGSVAWKPAGAYPSRTNPSNVAMATTDFQSVNWQQDKAVLPQVINPENNRLWTGNSRV
ECCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCHHCCCCCCEEEECCCEE
VSVEQQQLLGDGGYALGARSMQIRDRLFESDRFSVEDFYQLQLDNEARFLMDWQQLLLNQ
EEEEHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LSQQPERFAKDIEYLTSWQACACSDSVGYTLVRHFRTRVIDTTFAPIETELAKSELSLSA
HHHCHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IKRYLEPGIWQLINAQEPSWLPQDEHSWSGYLLQIYLNVKEASLAKYSDNNDMADLAWGK
HHHHHCCCCEEHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHEECCCCCCHHHCCCC
VNQLKIQHPFSKQIPALSSLLDMPVVEGFGDSFMPAVQGASFGASQRFIVQPGDEVNAIM
CCEEEEECCCHHCCHHHHHHHHCHHHHCCCCCHHHHHCCCCCCCCCEEEECCCCCCCEEE
TIPGGQSGHPLSAFYRSGFDDYVTQQSTPLLPGEAIHRLEITPEVKRGYE
ECCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCCHHEEEEECCHHHHCCCC
>Mature Secondary Structure
MHKTIKIALIGTSSVAAAVAGGLYLTLSLSLPKLDTDVISENIKQPVSLARDRLGTAIIH
CCCEEEEEEEECCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
ASDRQDAAYGLGYAHGQDRFFQMDLLRRNSAGELAEIFGEKALDLDKRRRFHQLRKRAEL
ECCCCCCHHCCCEECCCCCEEEEHHHHCCCCCHHHHHHCHHHCCHHHHHHHHHHHHHHHH
IVTKLDATHLKVLTTYAQGVNDALAAQSLSSFEYIVTGANPKPWVPADSLLVIYSMYLDL
EEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHEEEHHEEC
QGNTIKRDLALTQIQDLFGEKMVDFLIQPSQYQAALDGSQLALTAMPIPPLSNNMLAQAK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
FQQIAEPLDIGSNNWAVTGELTANGKAMLSDDMHLSFAVPIIWYRAQLNYQKEGVEQQVT
HHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCEEEEEEEEEEEEEECCCHHHCHHHHHC
GVSLPGAPAIVVGSNGKVAWGFTNAYIDTADWIAIDEQTPIYFEHETIALPDSEVSYTIE
CCCCCCCCEEEECCCCEEEEEEECCEECCCCEEEECCCCCEEEECCEEECCCCCEEEEEE
MSPFGPVKEVGDKRYALSWVGHSDYAVDMQLIELDSIGNVEQGIEVAEKMGIPVQNMLLV
ECCCCCHHHHCCCEEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEE
DSNGSVAWKPAGAYPSRTNPSNVAMATTDFQSVNWQQDKAVLPQVINPENNRLWTGNSRV
ECCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCHHCCCCCCEEEECCCEE
VSVEQQQLLGDGGYALGARSMQIRDRLFESDRFSVEDFYQLQLDNEARFLMDWQQLLLNQ
EEEEHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LSQQPERFAKDIEYLTSWQACACSDSVGYTLVRHFRTRVIDTTFAPIETELAKSELSLSA
HHHCHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
IKRYLEPGIWQLINAQEPSWLPQDEHSWSGYLLQIYLNVKEASLAKYSDNNDMADLAWGK
HHHHHCCCCEEHHCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHEECCCCCCHHHCCCC
VNQLKIQHPFSKQIPALSSLLDMPVVEGFGDSFMPAVQGASFGASQRFIVQPGDEVNAIM
CCEEEEECCCHHCCHHHHHHHHCHHHHCCCCCHHHHHCCCCCCCCCEEEECCCCCCCEEE
TIPGGQSGHPLSAFYRSGFDDYVTQQSTPLLPGEAIHRLEITPEVKRGYE
ECCCCCCCCCHHHHHHCCCHHHHCCCCCCCCCCHHEEEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]