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The map label for this gene is atoB [H]

Identifier: 157962604

GI number: 157962604

Start: 3400507

End: 3401697

Strand: Reverse

Name: atoB [H]

Synonym: Spea_2783

Alternate gene names: 157962604

Gene position: 3401697-3400507 (Counterclockwise)

Preceding gene: 157962605

Following gene: 157962603

Centisome position: 65.74

GC content: 52.56

Gene sequence:

>1191_bases
ATGAGTTCAGTTCAGTTAGAACAAGATATTGTTATTGTTGCCGCAAAGCGCACGCCAATGGGCGGGTTTCAGGGCGCTCT
TTCAAGTGTTGCCTCACCAAAGCTTGCTGCAACGGCGATTAAAGGCTTGATGCAACAAAGCGGTCTAGCAGGTGAGCTTG
TCGATGAAGTCTTGATGGGTTGTGTATTGCCAGCAGGCCTAGGCCAAGCTCCGGCACGCCAAGCGGCATTAGGCGCTGAG
TTACCTCTTTCTGTTGGTGCGACTACCGTTAACAAGGTGTGTGGTTCAGGCATGAAAACCGTGATGCTAGCGCATGACTT
AATTAAAGCGGGCAGCGCCAATGTGGTGGTAGCTGGTGGTATGGAAAGTATGAGCCAAGCGCCTTATCTACTAGATAAAG
CTCGTGGCGGCATGCGTATGGGGCATGGCAAAGTGATGGACCATATGTTCCTCGATGGTCTTGAAGATGCTTACACGGGT
GGCGCCATGGGCACGTTCGCGCAAAACACCGCCGATGACTTTAAGTTGACTCGAGAGCAGATGGACAGCTTTGCGCTGAA
CTCTTTAGAAAAAGCCAACGCCGCTATCGACTCGGGTGCCTTTAGCGATGAAATCGCTCCAGTAACAGTGGCGAATCGCC
GCGGCGATATAGTGGTCGATACCGATGAGCAGCCGGGTAATGCCCGTCCAGACAAAATCCCAACACTTCGCCCAGCCTTT
GCTAAAGACGGCACCATCACCGCCGCTAACTCAAGCTCCATCTCAGATGGCGCCGCGGCGCTGATGCTAATGACACGCGG
CCAAGCTGCCGAGCTAGGCCTCGAAGTAATGGCAACAATTAAAGGTCACACTACCCACGCACAAGAGCCTTCAATGTTCA
CCACCGCGCCAGTCGGTGCGATGAACAAACTGCTCGACAAAGTTAACTGGACTAAAGAAGAGGTCGACCTTTTTGAAATC
AACGAAGCCTTTGCCATGGTAACTATGCTGGCGATTTCAGAGCTTGGACTCGATGCTAGCAAGGTCAATGTTAATGGCGG
TGCTTGTGCGTTAGGCCACCCAATAGGCTGCTCTGGTGCGCGCCTATTAGTGACCTTGATTTATGCTCTAAAAGCACGCG
GCCTTAAGCGCGGTGTAGCGTCTCTGTGTATCGGTGGCGGCGAAGCGACAGCGATGGCTATTGAGCTTTAA

Upstream 100 bases:

>100_bases
AGCCTGAGAACAGTCAATAAACTAAGTCGCTCAACCCTACAACTAGCGCGGCTTTAGACGACTTCTAATAAAGGTTAACT
AGCGTATTACCGGAGTAATT

Downstream 100 bases:

>100_bases
AGCTTGTAATTACATTGAAATAGCAGCTTAAAACTAATCAACAAGACTCGATTTAACTTAGGACCAAGATATTGAAAGCG
ACGTTTTTGCTATCAATATG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSSVQLEQDIVIVAAKRTPMGGFQGALSSVASPKLAATAIKGLMQQSGLAGELVDEVLMGCVLPAGLGQAPARQAALGAE
LPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSANVVVAGGMESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTG
GAMGTFAQNTADDFKLTREQMDSFALNSLEKANAAIDSGAFSDEIAPVTVANRRGDIVVDTDEQPGNARPDKIPTLRPAF
AKDGTITAANSSSISDGAAALMLMTRGQAAELGLEVMATIKGHTTHAQEPSMFTTAPVGAMNKLLDKVNWTKEEVDLFEI
NEAFAMVTMLAISELGLDASKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL

Sequences:

>Translated_396_residues
MSSVQLEQDIVIVAAKRTPMGGFQGALSSVASPKLAATAIKGLMQQSGLAGELVDEVLMGCVLPAGLGQAPARQAALGAE
LPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSANVVVAGGMESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTG
GAMGTFAQNTADDFKLTREQMDSFALNSLEKANAAIDSGAFSDEIAPVTVANRRGDIVVDTDEQPGNARPDKIPTLRPAF
AKDGTITAANSSSISDGAAALMLMTRGQAAELGLEVMATIKGHTTHAQEPSMFTTAPVGAMNKLLDKVNWTKEEVDLFEI
NEAFAMVTMLAISELGLDASKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
>Mature_395_residues
SSVQLEQDIVIVAAKRTPMGGFQGALSSVASPKLAATAIKGLMQQSGLAGELVDEVLMGCVLPAGLGQAPARQAALGAEL
PLSVGATTVNKVCGSGMKTVMLAHDLIKAGSANVVVAGGMESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTGG
AMGTFAQNTADDFKLTREQMDSFALNSLEKANAAIDSGAFSDEIAPVTVANRRGDIVVDTDEQPGNARPDKIPTLRPAFA
KDGTITAANSSSISDGAAALMLMTRGQAAELGLEVMATIKGHTTHAQEPSMFTTAPVGAMNKLLDKVNWTKEEVDLFEIN
EAFAMVTMLAISELGLDASKVNVNGGACALGHPIGCSGARLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=45.6410256410256, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=44.7300771208226, Blast_Score=318, Evalue=7e-87,
Organism=Homo sapiens, GI167614485, Length=395, Percent_Identity=36.9620253164557, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI4501853, Length=406, Percent_Identity=36.2068965517241, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4504327, Length=426, Percent_Identity=30.2816901408451, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI194353979, Length=87, Percent_Identity=50.5747126436782, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082165, Length=389, Percent_Identity=45.2442159383033, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1788554, Length=390, Percent_Identity=50, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1787663, Length=392, Percent_Identity=38.0102040816327, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI48994986, Length=403, Percent_Identity=37.2208436724566, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1788683, Length=402, Percent_Identity=28.1094527363184, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25147385, Length=384, Percent_Identity=42.7083333333333, Blast_Score=305, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=40.4092071611253, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=35.6589147286822, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17535917, Length=392, Percent_Identity=33.9285714285714, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17551802, Length=423, Percent_Identity=29.5508274231678, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6325229, Length=396, Percent_Identity=46.7171717171717, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6322031, Length=387, Percent_Identity=35.4005167958656, Blast_Score=203, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24655093, Length=388, Percent_Identity=46.6494845360825, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24640423, Length=389, Percent_Identity=44.987146529563, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17648125, Length=392, Percent_Identity=36.2244897959184, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17137578, Length=423, Percent_Identity=32.1513002364066, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40811; Mature: 40679

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVQLEQDIVIVAAKRTPMGGFQGALSSVASPKLAATAIKGLMQQSGLAGELVDEVLMG
CCCCEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
CVLPAGLGQAPARQAALGAELPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSANVVVAGG
HHCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECC
MESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTGGAMGTFAQNTADDFKLTREQ
HHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHCCCHHHHHHHHHH
MDSFALNSLEKANAAIDSGAFSDEIAPVTVANRRGDIVVDTDEQPGNARPDKIPTLRPAF
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCC
AKDGTITAANSSSISDGAAALMLMTRGQAAELGLEVMATIKGHTTHAQEPSMFTTAPVGA
CCCCEEEECCCCCCCCHHHEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHH
MNKLLDKVNWTKEEVDLFEINEAFAMVTMLAISELGLDASKVNVNGGACALGHPIGCSGA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCHH
RLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
>Mature Secondary Structure 
SSVQLEQDIVIVAAKRTPMGGFQGALSSVASPKLAATAIKGLMQQSGLAGELVDEVLMG
CCCEECCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
CVLPAGLGQAPARQAALGAELPLSVGATTVNKVCGSGMKTVMLAHDLIKAGSANVVVAGG
HHCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECC
MESMSQAPYLLDKARGGMRMGHGKVMDHMFLDGLEDAYTGGAMGTFAQNTADDFKLTREQ
HHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCHHHCCCHHHHHHHHHH
MDSFALNSLEKANAAIDSGAFSDEIAPVTVANRRGDIVVDTDEQPGNARPDKIPTLRPAF
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCC
AKDGTITAANSSSISDGAAALMLMTRGQAAELGLEVMATIKGHTTHAQEPSMFTTAPVGA
CCCCEEEECCCCCCCCHHHEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCHHH
MNKLLDKVNWTKEEVDLFEINEAFAMVTMLAISELGLDASKVNVNGGACALGHPIGCSGA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCCCHH
RLLVTLIYALKARGLKRGVASLCIGGGEATAMAIEL
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]