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The map label for this gene is fadR [H]

Identifier: 157962259

GI number: 157962259

Start: 2982409

End: 2983128

Strand: Reverse

Name: fadR [H]

Synonym: Spea_2438

Alternate gene names: 157962259

Gene position: 2983128-2982409 (Counterclockwise)

Preceding gene: 157962262

Following gene: 157962256

Centisome position: 57.65

GC content: 42.78

Gene sequence:

>720_bases
ATGATCATCAATGCCAAAGGTCCTGCAAGCTTTGCAGAGAAGTATATTGTGCGATCCATATGGGAAGATAAGTTTCCGCC
AGGCTCTATTCTGCCCGCAGAACGCGAGCTTTCAGAACTGATTGGTGTAACTCGTACAACATTACGAGAAGTGCTACAAC
GTTTGGCTCGTGATGGATGGTTGACGATTCAACATGGTAAGCCAACAAGAGTGAATAACTTTTGGGAAACGTCTGGTTTG
AATATTTTGGAAACTATCGCCGAATTGAATCCCGATGGTTTTCCTGAACTCGTTGACCAATTGCTATCTGCGAGAAGTAG
CGTCAGTGCGATCTATTTTAGAGGTGCTATCCGTAACAATCCTGAAGAAGCGATAGAAGCCTTATCTCATCTTTCTGAGC
TTGAAGATACGGCTCAAGCATATGCTGAGTTTGACTATCAGCTACAGCACACTTTAGCATTTTCATCAGGAAATCCACTT
TACGTGTTAATCTTGAATGGCTTTAAAGGTTTATATAGTCGAGTCGGGCGTTACTATTTCTCAAGCGCTGAAGCCCGCGC
ATTAGCAATGGATTTTTATAAGCAGTTGCAGCAACTTGCGATTGACAAAAACTATACCGACGTGCCGGCATTAATGCGTA
CTTATGGCATTAATAGTGGTGTGATGTGGCAGAGTCTTCGAGATGATATGCCTGTCGACTTAGGTTATTCAGATAACTAA

Upstream 100 bases:

>100_bases
GGATGGATACCGTCTAATCGGTCTGTTTTGGTTTTTCATTTCTCGCCGCTCTGGTATGATCTGTCCAAGAACAACACTAA
TAATTGGGTAGAGTAGGTTA

Downstream 100 bases:

>100_bases
ATATTCAGATGACTAAAGCTGGTCAGTCAGGTAACCAAAGCAAATAACAATTATCTGTCATTCTGTATTAAACAAAAGCC
ATCGTGAAGATGGCTTTTTT

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MIINAKGPASFAEKYIVRSIWEDKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNNPEEAIEALSHLSELEDTAQAYAEFDYQLQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVDLGYSDN

Sequences:

>Translated_239_residues
MIINAKGPASFAEKYIVRSIWEDKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNNPEEAIEALSHLSELEDTAQAYAEFDYQLQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVDLGYSDN
>Mature_239_residues
MIINAKGPASFAEKYIVRSIWEDKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTRVNNFWETSGL
NILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNNPEEAIEALSHLSELEDTAQAYAEFDYQLQHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFSSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVDLGYSDN

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=234, Percent_Identity=59.4017094017094, Blast_Score=301, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26982; Mature: 26982

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWEDKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNN
EEEECCCCCCCCCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PEEAIEALSHLSELEDTAQAYAEFDYQLQHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVDLGYSDN
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWEDKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTIQHGKPTRVNNFWETSGLNILETIAELNPDGFPELVDQLLSARSSVSAIYFRGAIRNN
EEEECCCCCCCCCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PEEAIEALSHLSELEDTAQAYAEFDYQLQHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHH
SSAEARALAMDFYKQLQQLAIDKNYTDVPALMRTYGINSGVMWQSLRDDMPVDLGYSDN
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA