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The map label for this gene is ruvA [H]

Identifier: 157962184

GI number: 157962184

Start: 2881574

End: 2882191

Strand: Reverse

Name: ruvA [H]

Synonym: Spea_2363

Alternate gene names: 157962184

Gene position: 2882191-2881574 (Counterclockwise)

Preceding gene: 157962185

Following gene: 157962183

Centisome position: 55.7

GC content: 43.69

Gene sequence:

>618_bases
ATGATAGGTCGTATTCGCGGAATACTTATTGAGAAACAGGCACCAGAAGTTCTGGTCGATGTTTCTGGAGTCGGTTATGA
GCTTCAAATGCCACTCACCAGCTTTTACGAGCTACCTGAGCTTGGGCAAGAGGCCGTTATTTATACTCACTTTGTGGTGA
GAGAAGATGCGCAGTTGTTATACGGCTTCGTATCGAAACAAGAAAGAAGTCTGTTTCGATTGCTTATCAAGGCTAATGGC
GTTGGACCAAAACTGGGTTTAACGATTTTATCAGGTATGACAGCGGGTGAATTTGTTGCTTGTGTTGAACGAGATGATAT
CGCGACTTTGGTTAAATTACCCGGCGTAGGTAAAAAAACCGCCGAGCGCTTATTGGTCGAAATGCGCGATAAGTTAAAGA
GCTTAATGGAAGCTTCTGTCGGCTCTGAGCGCGAGTTTATGCTGCAATCAAATTACAAGGCGTCAGAAGTTGTAAACACA
GCTGAAGAAGACGCAATTGCTGCACTGTTATCACTGGGTTATAAACCTGCCCAAGCGAGCAAAGCAGTATCATCAGTTTA
TACCGATGGTATGAGTTCAGAAACGCTGATTAAATCTGCATTGAAATCGATGCTGTAA

Upstream 100 bases:

>100_bases
CCGCTGATGCGCTTGGTGTGGCTGTGTGTCATTATCACACGAGTCAGAGTCTAGTTGCCTTGGCTGGCAGAGCAAATGTA
AGAACATATGGACGATATAA

Downstream 100 bases:

>100_bases
GGGAAAAAGATGATTGAAGCAGATCGACTTATACAACCGAACATAATAGAGCGCGATGAAATCGAAGCCGTTGATCGCGC
TATGCGTCCGAAGATGCTGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGRIRGILIEKQAPEVLVDVSGVGYELQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFVSKQERSLFRLLIKANG
VGPKLGLTILSGMTAGEFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYKASEVVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML

Sequences:

>Translated_205_residues
MIGRIRGILIEKQAPEVLVDVSGVGYELQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFVSKQERSLFRLLIKANG
VGPKLGLTILSGMTAGEFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYKASEVVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML
>Mature_205_residues
MIGRIRGILIEKQAPEVLVDVSGVGYELQMPLTSFYELPELGQEAVIYTHFVVREDAQLLYGFVSKQERSLFRLLIKANG
VGPKLGLTILSGMTAGEFVACVERDDIATLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFMLQSNYKASEVVNT
AEEDAIAALLSLGYKPAQASKAVSSVYTDGMSSETLIKSALKSML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=60.4878048780488, Blast_Score=254, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22354; Mature: 22354

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIRGILIEKQAPEVLVDVSGVGYELQMPLTSFYELPELGQEAVIYTHFVVREDAQLL
CCCCHHEEEEECCCCCEEEEECCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGFVSKQERSLFRLLIKANGVGPKLGLTILSGMTAGEFVACVERDDIATLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHEEECCCCCHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFMLQSNYKASEVVNTAEEDAIAALLSLGYKPAQAS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
KAVSSVYTDGMSSETLIKSALKSML
HHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIRGILIEKQAPEVLVDVSGVGYELQMPLTSFYELPELGQEAVIYTHFVVREDAQLL
CCCCHHEEEEECCCCCEEEEECCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YGFVSKQERSLFRLLIKANGVGPKLGLTILSGMTAGEFVACVERDDIATLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHEEECCCCCHHHHHHCCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFMLQSNYKASEVVNTAEEDAIAALLSLGYKPAQAS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
KAVSSVYTDGMSSETLIKSALKSML
HHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA