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The map label for this gene is ruvB [H]

Identifier: 157962183

GI number: 157962183

Start: 2880551

End: 2881564

Strand: Reverse

Name: ruvB [H]

Synonym: Spea_2362

Alternate gene names: 157962183

Gene position: 2881564-2880551 (Counterclockwise)

Preceding gene: 157962184

Following gene: 157962182

Centisome position: 55.69

GC content: 45.86

Gene sequence:

>1014_bases
ATGATTGAAGCAGATCGACTTATACAACCGAACATAATAGAGCGCGATGAAATCGAAGCCGTTGATCGCGCTATGCGTCC
GAAGATGCTGGATGAGTATACCGGTCAGGATGATACTCGCGCGCAGCTTAAGATTTTTATTCAAGCAGCGCAAAAACGAG
GGGAAGCACTGGATCATATGCTGATTTATGGTCCTCCAGGTTTAGGTAAAACCACCTTGGCAATGATTGTAGCCAATGAA
ATGGGAGTGAACATTAAGTCAACTTCCGGCCCAGTTTTAGAAAAGGCTGGCGACTTAGCTGCCTTGTTAACTAACCTTGA
GCCAAATGATGTATTGTTTATTGACGAAATTCATCGTTTAAGCCCCGTGGTTGAAGAGATTTTATATCCAGCTATGGAAG
ATTATCAGCTAGATATCATGATTGGAGAGGGCCCGGCCGCGCGTTCAATCAAGCTAGATCTGCCGCCATTTACACTGGTC
GGTGCAACGACCCGTGCAGGTGCATTAACTTCGCCTTTAAGAGCTCGTTTCGGAATTCCACTTAGACTCGAGTTCTACAA
TGTTAAAGACCTATCAAGCATTGTGACTCGCTCCGCTAAAGTCATGGATCTTGCTATCGATGACGAAGGTGCGATTGAAA
TTGCACGTCGCTCTCGTGGTACACCACGTATCGCTAATCGCCTACTCAGGCGCGTGCGTGACTTTGCCGAAGTTAAACAT
CGCGGTGAAGTGACTAAAATTATCGCCGAAGAAGCACTCGATATGCTTGATGTTGACGCGGAAGGCTTTGACTATATGGA
TAGAAAGTTGTTGTTGGCAATTATCGACAAATTTATGGGCGGCCCAGTAGGTTTAGATAATCTCGCGGCGGCTATCGGCG
AAGAGCGAGAAACGATTGAAGATGTGTTAGAGCCTTTTTTAATTCAGCAAGGCTTTATACAGAGAACGCCAAGAGGGCGC
ATTGCCACTCCTAGAGCCTATAGCCACTTTAATATCATTCAGCCAGTGTCTTAA

Upstream 100 bases:

>100_bases
TGCCCAAGCGAGCAAAGCAGTATCATCAGTTTATACCGATGGTATGAGTTCAGAAACGCTGATTAAATCTGCATTGAAAT
CGATGCTGTAAGGGAAAAAG

Downstream 100 bases:

>100_bases
CCCTGCTAGGGATCTTCTTTATTTCAGAGCGTTAAACTCAGCTAGATGCTTTCTATACTTTCTATATTAGAGGAGTGAGA
TGTGAATGCTCCTCAATATA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIEADRLIQPNIIERDEIEAVDRAMRPKMLDEYTGQDDTRAQLKIFIQAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVTRSAKVMDLAIDDEGAIEIARRSRGTPRIANRLLRRVRDFAEVKH
RGEVTKIIAEEALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYSHFNIIQPVS

Sequences:

>Translated_337_residues
MIEADRLIQPNIIERDEIEAVDRAMRPKMLDEYTGQDDTRAQLKIFIQAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVTRSAKVMDLAIDDEGAIEIARRSRGTPRIANRLLRRVRDFAEVKH
RGEVTKIIAEEALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYSHFNIIQPVS
>Mature_337_residues
MIEADRLIQPNIIERDEIEAVDRAMRPKMLDEYTGQDDTRAQLKIFIQAAQKRGEALDHMLIYGPPGLGKTTLAMIVANE
MGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLV
GATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVTRSAKVMDLAIDDEGAIEIARRSRGTPRIANRLLRRVRDFAEVKH
RGEVTKIIAEEALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGR
IATPRAYSHFNIIQPVS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=335, Percent_Identity=77.0149253731343, Blast_Score=526, Evalue=1e-151,
Organism=Escherichia coli, GI1787119, Length=233, Percent_Identity=28.3261802575107, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37471; Mature: 37471

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIQPNIIERDEIEAVDRAMRPKMLDEYTGQDDTRAQLKIFIQAAQKRGEALDHM
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCE
LIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHCHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIP
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCC
LRLEFYNVKDLSSIVTRSAKVMDLAIDDEGAIEIARRSRGTPRIANRLLRRVRDFAEVKH
EEEEEECHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RGEVTKIIAEEALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
DVLEPFLIQQGFIQRTPRGRIATPRAYSHFNIIQPVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MIEADRLIQPNIIERDEIEAVDRAMRPKMLDEYTGQDDTRAQLKIFIQAAQKRGEALDHM
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCE
LIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRL
EEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHCHHHHHHHCCCCCCEEEHHHHHHH
SPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIP
HHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCC
LRLEFYNVKDLSSIVTRSAKVMDLAIDDEGAIEIARRSRGTPRIANRLLRRVRDFAEVKH
EEEEEECHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RGEVTKIIAEEALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
DVLEPFLIQQGFIQRTPRGRIATPRAYSHFNIIQPVS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA