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The map label for this gene is ydjJ [C]

Identifier: 157962107

GI number: 157962107

Start: 2769030

End: 2770064

Strand: Reverse

Name: ydjJ [C]

Synonym: Spea_2286

Alternate gene names: 157962107

Gene position: 2770064-2769030 (Counterclockwise)

Preceding gene: 157962110

Following gene: 157962106

Centisome position: 53.53

GC content: 47.54

Gene sequence:

>1035_bases
ATGAAAGCTTTGGTACTAGAAAAAGTAAATGAACTTGCCTTAAAAGAGGTAATGACGCCTACAGAAGTCGGTGCAAATGA
TGTAAAAATTAAAATTCAAGCCGTTGGTATATGTGGCTCAGACGTTCATTACCTTTCTCATGGCCGTATAGGACATTTTG
TCGTTGAAAAACCAATGATCCTCGGCCATGAAGCGGCAGGTATCGTCACCGCGGTAGGTAGCAATGTTAAGCACCTTAAA
GAGGGGGACCGAGTCTGTATGGAGCCGGGCATACCTCAGCCACAGTCAGCAGAGACTATGGAGGGGATCTATAACCTAGA
TCCGGATGTGCAGTTTTGGGCTACGCCTCCTTACGACGGTTGCTGCTCTGAGTTTGTGGTACACCCTGCGGCTTTCACCT
TTAAAATCCCTCAGCATATGAGCTATGCAGAAGGTGCCATGGTTGAGCCTTTAGCTATCGGCATGCAGGCTGCGACTAAA
GCCGAAATTAAACCGGGCGATATTGGCCTAGTTTACGGCGCGGGTACAATTGGCGTTATGTGCGCACTATCAGCGTTGGC
GAGTGGCTGCGCTGAAGTCATCGTTGTCGACGTCGTCAATGAAAAGTTAGCTACGGTTAATGACTATGAAGGCATTACCG
TGGTTAACAGCTTGACCCAAGATGTGGCTGAGGTGGTTGCGGCTAAAACTGGCGGCCGTGGCGTCAATGTGGTGTTTGAA
TGTTGCGGCGTTGAAGCGGTGATTACCCGTATCTGCCAGCACGTTGCAGCAAATGGCACAGTCGTTTTAGTGGGAATGCC
TGTAGAGCCTGTTAAATTCGATATCGTTGCGGCTCAGGTTAAAGAAATCACGTTCAAGACCATCTTCCGTTACGCCAATA
TGTACCCTAAAACCATCAACCTTATCGCTTCAGGCAAGTTAAACGTCAAGCCGTTGATCAGCAAGACCTATAAGTTTGAA
GATTCACTAAAGGCCTATGCTAGAGCACTTGAAGCGAACCCTTCAGATGTAAAGATCATGATAGAGATGGAGTAA

Upstream 100 bases:

>100_bases
TTTTGTGAGTTTTAGCGCAAAAGCTTTTCAAGTAAAAGATTATCTTAAATGAAAGTGTTAATGACATCGATAACATTGTT
TTGATAAAGGGAACCATTAC

Downstream 100 bases:

>100_bases
GCGATGAATATTGTCGCGGGTGTCGATTGTGGCACACAGGGCACTAAGGTCATTCTGGTTGATTTAGGCACATCTCGTGT
GTTGGCTGAATGTTCTGCTC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKALVLEKVNELALKEVMTPTEVGANDVKIKIQAVGICGSDVHYLSHGRIGHFVVEKPMILGHEAAGIVTAVGSNVKHLK
EGDRVCMEPGIPQPQSAETMEGIYNLDPDVQFWATPPYDGCCSEFVVHPAAFTFKIPQHMSYAEGAMVEPLAIGMQAATK
AEIKPGDIGLVYGAGTIGVMCALSALASGCAEVIVVDVVNEKLATVNDYEGITVVNSLTQDVAEVVAAKTGGRGVNVVFE
CCGVEAVITRICQHVAANGTVVLVGMPVEPVKFDIVAAQVKEITFKTIFRYANMYPKTINLIASGKLNVKPLISKTYKFE
DSLKAYARALEANPSDVKIMIEME

Sequences:

>Translated_344_residues
MKALVLEKVNELALKEVMTPTEVGANDVKIKIQAVGICGSDVHYLSHGRIGHFVVEKPMILGHEAAGIVTAVGSNVKHLK
EGDRVCMEPGIPQPQSAETMEGIYNLDPDVQFWATPPYDGCCSEFVVHPAAFTFKIPQHMSYAEGAMVEPLAIGMQAATK
AEIKPGDIGLVYGAGTIGVMCALSALASGCAEVIVVDVVNEKLATVNDYEGITVVNSLTQDVAEVVAAKTGGRGVNVVFE
CCGVEAVITRICQHVAANGTVVLVGMPVEPVKFDIVAAQVKEITFKTIFRYANMYPKTINLIASGKLNVKPLISKTYKFE
DSLKAYARALEANPSDVKIMIEME
>Mature_344_residues
MKALVLEKVNELALKEVMTPTEVGANDVKIKIQAVGICGSDVHYLSHGRIGHFVVEKPMILGHEAAGIVTAVGSNVKHLK
EGDRVCMEPGIPQPQSAETMEGIYNLDPDVQFWATPPYDGCCSEFVVHPAAFTFKIPQHMSYAEGAMVEPLAIGMQAATK
AEIKPGDIGLVYGAGTIGVMCALSALASGCAEVIVVDVVNEKLATVNDYEGITVVNSLTQDVAEVVAAKTGGRGVNVVFE
CCGVEAVITRICQHVAANGTVVLVGMPVEPVKFDIVAAQVKEITFKTIFRYANMYPKTINLIASGKLNVKPLISKTYKFE
DSLKAYARALEANPSDVKIMIEME

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=346, Percent_Identity=39.3063583815029, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI4501933, Length=327, Percent_Identity=28.4403669724771, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501929, Length=330, Percent_Identity=29.6969696969697, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI34577061, Length=329, Percent_Identity=28.8753799392097, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71565154, Length=362, Percent_Identity=26.2430939226519, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788073, Length=333, Percent_Identity=36.9369369369369, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1790718, Length=300, Percent_Identity=28.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790045, Length=331, Percent_Identity=30.2114803625378, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787863, Length=334, Percent_Identity=26.3473053892216, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788407, Length=352, Percent_Identity=25.2840909090909, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082125, Length=353, Percent_Identity=28.0453257790368, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI226510992, Length=345, Percent_Identity=27.536231884058, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788075, Length=313, Percent_Identity=27.1565495207668, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081918, Length=248, Percent_Identity=30.241935483871, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=333, Percent_Identity=41.1411411411411, Blast_Score=260, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI17562878, Length=340, Percent_Identity=40, Blast_Score=242, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6323099, Length=347, Percent_Identity=41.7867435158501, Blast_Score=275, Evalue=7e-75,
Organism=Saccharomyces cerevisiae, GI6322619, Length=346, Percent_Identity=41.0404624277457, Blast_Score=255, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6319955, Length=346, Percent_Identity=41.0404624277457, Blast_Score=255, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6319257, Length=377, Percent_Identity=25.4641909814324, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=293, Percent_Identity=30.3754266211604, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17137530, Length=344, Percent_Identity=38.3720930232558, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI17737897, Length=343, Percent_Identity=38.4839650145773, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI45550770, Length=308, Percent_Identity=28.8961038961039, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45551930, Length=308, Percent_Identity=28.8961038961039, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221457811, Length=308, Percent_Identity=28.8961038961039, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 36797; Mature: 36797

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVLEKVNELALKEVMTPTEVGANDVKIKIQAVGICGSDVHYLSHGRIGHFVVEKPMI
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCHHHCCCCEEEEEECCCEE
LGHEAAGIVTAVGSNVKHLKEGDRVCMEPGIPQPQSAETMEGIYNLDPDVQFWATPPYDG
ECCCCCCHHHHHCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCH
CCSEFVVHPAAFTFKIPQHMSYAEGAMVEPLAIGMQAATKAEIKPGDIGLVYGAGTIGVM
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCEEEEECCHHHHHH
CALSALASGCAEVIVVDVVNEKLATVNDYEGITVVNSLTQDVAEVVAAKTGGRGVNVVFE
HHHHHHHCCHHHEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
CCGVEAVITRICQHVAANGTVVLVGMPVEPVKFDIVAAQVKEITFKTIFRYANMYPKTIN
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
LIASGKLNVKPLISKTYKFEDSLKAYARALEANPSDVKIMIEME
EEECCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MKALVLEKVNELALKEVMTPTEVGANDVKIKIQAVGICGSDVHYLSHGRIGHFVVEKPMI
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCHHHCCCCEEEEEECCCEE
LGHEAAGIVTAVGSNVKHLKEGDRVCMEPGIPQPQSAETMEGIYNLDPDVQFWATPPYDG
ECCCCCCHHHHHCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCH
CCSEFVVHPAAFTFKIPQHMSYAEGAMVEPLAIGMQAATKAEIKPGDIGLVYGAGTIGVM
HHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCEEEEECCHHHHHH
CALSALASGCAEVIVVDVVNEKLATVNDYEGITVVNSLTQDVAEVVAAKTGGRGVNVVFE
HHHHHHHCCHHHEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
CCGVEAVITRICQHVAANGTVVLVGMPVEPVKFDIVAAQVKEITFKTIFRYANMYPKTIN
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
LIASGKLNVKPLISKTYKFEDSLKAYARALEANPSDVKIMIEME
EEECCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3886639 [H]