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The map label for this gene is hlyB [H]

Identifier: 157962063

GI number: 157962063

Start: 2717834

End: 2719828

Strand: Reverse

Name: hlyB [H]

Synonym: Spea_2242

Alternate gene names: 157962063

Gene position: 2719828-2717834 (Counterclockwise)

Preceding gene: 157962064

Following gene: 157962060

Centisome position: 52.56

GC content: 45.86

Gene sequence:

>1995_bases
ATGAAGCGGACTATCATTGCTAATCTCAGCTTAAAGCAGAAGTTTTTTGTCCTTATCCTACCGCCACTCATTGCATCAGT
CATTTTCGGTGGTCTCTACGCTAAAACCCAATACCAATTAAAGAGCGAGCTTACTGAGGTTTTGGTGTTAAGCGAATTGG
CTGTGACCAACAGTAACTTAGTTCATGAAATCCAAAAAGAGCGAGGCATGAGTGCTGGGTTTATCGGCTCCCAAGGCCAA
TCGTTTTCTCAGAAACTTCCACAGCAGCATGATGCAACGGACGCTTTGCTTAACAGTTACCAGCAATTTCTTAAAAGCCA
TGAACTCCCAACTGCATTTGCGACACAAATTGCACGAGTAGAAAGCCTGCTTAGCCAGATCCCCGATATACGTACTCGTG
TTGAAGGTTTATCTATTTCTGTCGCCGAAGAGGTAAAGTTCTACACCCAGGTTAATGCACTATTACTGAGTATTGTTGAC
TTGACGGCAAATAATGCCGCTAACCAAGAGATAGCTATAAGAGCTGCAGCATTTTCGGCATATTTGCAAATGAAGGAGAG
AGCAGGCATAGAGCGAGCAGTACTCAGTTCAACTTTTGGCAATATGGGGTTTAAAGAAGATGTCTATCGCCGCTTTGTAA
CCTTAGTGGCAGAGCAGGCCAGTTATCAAGAGCGTTTCTTAGCCTTAGCCGATGAACAAAGTAAGACAAACTATCAAGCA
CTGTTAAATACCAATGCAGTTAAAGATGTTAACCAGTATAGAAACATCGCTTTTAAGCAGATAACTTCTGAGATTGCAGC
GCAGAAAGCTGAATCCTGGTTTCAAACGTCCACCCAACGGATTGAGTTATTAAGAGAATTTGAACATGCGCTGTCAACCG
AGCTTATCAATGTGACCAAGCAGCGTTTATCGGCGGCCAGCCAAAGTTTTTACATCACATTATTAGGACTGCTGTTCGGC
GCAGGGATTGTACTGACTCTCTCTATCTCTGTACTGCGCTATATTCATGGCAGTGTTGCCAACTTGCACAACAGTGTCAC
TCGAGCTAGGGCAAACTTTGATCTTAGCATCCGTATTGATCAACAGAGTAAAGATGAATTTGGTGAGTTGGCTCTGGCCT
TTAATGACATGATGTCTGACTTTGAGCGCGTGATTGAACACGTACGTATTAATTCGACCTCTTTATTGACTGCTGTCTCT
CAGATGGAGCAATACTCTACTCAACTACGTCAAGATGTAGAGCTTGGCCATGGCGAAGCTGAGCAGGTTGCTTCTGCGAT
GACAGAGATGAGTGCCACGGTTGCCGAAATCGCTATCAATGCAGAGCGGGCATCAGAGGCCTCGACTCAGGCGAATATTG
AGGCTAAAGAGGGCAATGCCGAGGTAGGGCGTACCAGTGATGCCATTGGTGTACTCGCGGGTGATATTCGTGATTCAGCA
CAGGCATTGCAGCAACTCGAGCAAGATATTCAAAGCATTGTCACTGTGTCAGATGTGATCAGTGGTATTGCCGACCAGAC
AAACCTACTGGCTCTTAATGCTGCAATCGAAGCGGCTAGAGCCGGAGAGTCAGGCAGAGGATTTGCCGTCGTCGCCGATG
AGGTTCGTGGGCTCGCTCAGCGGGCACAAACGGCAACGGGTGATATTAAATCCATGACTGAACGTTTACGTAGTGGTGCT
AACACTGCGGTATTGGCGATGGAGCGTGGAACTAAGCAGACCAACGAAAGTGTTGTAGAAGCAAACCGAGCCAGTAGCGA
ACTAGATAAAATAGTCGATCATATTGGTGTTATCGAGAGTATGAACGAGCAGATCGCAGCATCGACTCATGAGCAAACGG
CCGTGGCTGAAGAAGTGAATCGAAATGCGCAGAAAATTAGCGAGATCTATCTGCAAACTCACAGCGTGGCAGATCAGCTA
AGCGTTCTAACTGATAAACTCGTTGAGGACACGGCAGAGATGTCGAAAGAGGTGCAAAAATTCAAGTTAAGTTAA

Upstream 100 bases:

>100_bases
GCTTTTTTTTCAAAAAATTTAAGAAATCTATTTACCTACAGTAGGTTTCGACTATGCTATTGCAACAATAAAATAATATT
TAAACAGGGTTGTTTAACAT

Downstream 100 bases:

>100_bases
TCCATTAACTATTTTGTGCGGAATTGGCTAGCAATTATGCAAACGTTTGAGATTACGGTAATTTGGCTTGACGCAATTGT
GCCTTTTAAGTAAAGTAGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKRTIIANLSLKQKFFVLILPPLIASVIFGGLYAKTQYQLKSELTEVLVLSELAVTNSNLVHEIQKERGMSAGFIGSQGQ
SFSQKLPQQHDATDALLNSYQQFLKSHELPTAFATQIARVESLLSQIPDIRTRVEGLSISVAEEVKFYTQVNALLLSIVD
LTANNAANQEIAIRAAAFSAYLQMKERAGIERAVLSSTFGNMGFKEDVYRRFVTLVAEQASYQERFLALADEQSKTNYQA
LLNTNAVKDVNQYRNIAFKQITSEIAAQKAESWFQTSTQRIELLREFEHALSTELINVTKQRLSAASQSFYITLLGLLFG
AGIVLTLSISVLRYIHGSVANLHNSVTRARANFDLSIRIDQQSKDEFGELALAFNDMMSDFERVIEHVRINSTSLLTAVS
QMEQYSTQLRQDVELGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANIEAKEGNAEVGRTSDAIGVLAGDIRDSA
QALQQLEQDIQSIVTVSDVISGIADQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQRAQTATGDIKSMTERLRSGA
NTAVLAMERGTKQTNESVVEANRASSELDKIVDHIGVIESMNEQIAASTHEQTAVAEEVNRNAQKISEIYLQTHSVADQL
SVLTDKLVEDTAEMSKEVQKFKLS

Sequences:

>Translated_664_residues
MKRTIIANLSLKQKFFVLILPPLIASVIFGGLYAKTQYQLKSELTEVLVLSELAVTNSNLVHEIQKERGMSAGFIGSQGQ
SFSQKLPQQHDATDALLNSYQQFLKSHELPTAFATQIARVESLLSQIPDIRTRVEGLSISVAEEVKFYTQVNALLLSIVD
LTANNAANQEIAIRAAAFSAYLQMKERAGIERAVLSSTFGNMGFKEDVYRRFVTLVAEQASYQERFLALADEQSKTNYQA
LLNTNAVKDVNQYRNIAFKQITSEIAAQKAESWFQTSTQRIELLREFEHALSTELINVTKQRLSAASQSFYITLLGLLFG
AGIVLTLSISVLRYIHGSVANLHNSVTRARANFDLSIRIDQQSKDEFGELALAFNDMMSDFERVIEHVRINSTSLLTAVS
QMEQYSTQLRQDVELGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANIEAKEGNAEVGRTSDAIGVLAGDIRDSA
QALQQLEQDIQSIVTVSDVISGIADQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQRAQTATGDIKSMTERLRSGA
NTAVLAMERGTKQTNESVVEANRASSELDKIVDHIGVIESMNEQIAASTHEQTAVAEEVNRNAQKISEIYLQTHSVADQL
SVLTDKLVEDTAEMSKEVQKFKLS
>Mature_664_residues
MKRTIIANLSLKQKFFVLILPPLIASVIFGGLYAKTQYQLKSELTEVLVLSELAVTNSNLVHEIQKERGMSAGFIGSQGQ
SFSQKLPQQHDATDALLNSYQQFLKSHELPTAFATQIARVESLLSQIPDIRTRVEGLSISVAEEVKFYTQVNALLLSIVD
LTANNAANQEIAIRAAAFSAYLQMKERAGIERAVLSSTFGNMGFKEDVYRRFVTLVAEQASYQERFLALADEQSKTNYQA
LLNTNAVKDVNQYRNIAFKQITSEIAAQKAESWFQTSTQRIELLREFEHALSTELINVTKQRLSAASQSFYITLLGLLFG
AGIVLTLSISVLRYIHGSVANLHNSVTRARANFDLSIRIDQQSKDEFGELALAFNDMMSDFERVIEHVRINSTSLLTAVS
QMEQYSTQLRQDVELGHGEAEQVASAMTEMSATVAEIAINAERASEASTQANIEAKEGNAEVGRTSDAIGVLAGDIRDSA
QALQQLEQDIQSIVTVSDVISGIADQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQRAQTATGDIKSMTERLRSGA
NTAVLAMERGTKQTNESVVEANRASSELDKIVDHIGVIESMNEQIAASTHEQTAVAEEVNRNAQKISEIYLQTHSVADQL
SVLTDKLVEDTAEMSKEVQKFKLS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=251, Percent_Identity=35.0597609561753, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1787690, Length=394, Percent_Identity=28.6802030456853, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=31.986531986532, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788194, Length=300, Percent_Identity=29.6666666666667, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1789453, Length=298, Percent_Identity=30.2013422818792, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72785; Mature: 72785

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTIIANLSLKQKFFVLILPPLIASVIFGGLYAKTQYQLKSELTEVLVLSELAVTNSNL
CCCEEEECCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VHEIQKERGMSAGFIGSQGQSFSQKLPQQHDATDALLNSYQQFLKSHELPTAFATQIARV
HHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ESLLSQIPDIRTRVEGLSISVAEEVKFYTQVNALLLSIVDLTANNAANQEIAIRAAAFSA
HHHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YLQMKERAGIERAVLSSTFGNMGFKEDVYRRFVTLVAEQASYQERFLALADEQSKTNYQA
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LLNTNAVKDVNQYRNIAFKQITSEIAAQKAESWFQTSTQRIELLREFEHALSTELINVTK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSAASQSFYITLLGLLFGAGIVLTLSISVLRYIHGSVANLHNSVTRARANFDLSIRID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
QQSKDEFGELALAFNDMMSDFERVIEHVRINSTSLLTAVSQMEQYSTQLRQDVELGHGEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EQVASAMTEMSATVAEIAINAERASEASTQANIEAKEGNAEVGRTSDAIGVLAGDIRDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
QALQQLEQDIQSIVTVSDVISGIADQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
RAQTATGDIKSMTERLRSGANTAVLAMERGTKQTNESVVEANRASSELDKIVDHIGVIES
HHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNEQIAASTHEQTAVAEEVNRNAQKISEIYLQTHSVADQLSVLTDKLVEDTAEMSKEVQK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLS
HCCC
>Mature Secondary Structure
MKRTIIANLSLKQKFFVLILPPLIASVIFGGLYAKTQYQLKSELTEVLVLSELAVTNSNL
CCCEEEECCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VHEIQKERGMSAGFIGSQGQSFSQKLPQQHDATDALLNSYQQFLKSHELPTAFATQIARV
HHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ESLLSQIPDIRTRVEGLSISVAEEVKFYTQVNALLLSIVDLTANNAANQEIAIRAAAFSA
HHHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YLQMKERAGIERAVLSSTFGNMGFKEDVYRRFVTLVAEQASYQERFLALADEQSKTNYQA
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LLNTNAVKDVNQYRNIAFKQITSEIAAQKAESWFQTSTQRIELLREFEHALSTELINVTK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSAASQSFYITLLGLLFGAGIVLTLSISVLRYIHGSVANLHNSVTRARANFDLSIRID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
QQSKDEFGELALAFNDMMSDFERVIEHVRINSTSLLTAVSQMEQYSTQLRQDVELGHGEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EQVASAMTEMSATVAEIAINAERASEASTQANIEAKEGNAEVGRTSDAIGVLAGDIRDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
QALQQLEQDIQSIVTVSDVISGIADQTNLLALNAAIEAARAGESGRGFAVVADEVRGLAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
RAQTATGDIKSMTERLRSGANTAVLAMERGTKQTNESVVEANRASSELDKIVDHIGVIES
HHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNEQIAASTHEQTAVAEEVNRNAQKISEIYLQTHSVADQLSVLTDKLVEDTAEMSKEVQK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]