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The map label for this gene is nadA [H]

Identifier: 157962064

GI number: 157962064

Start: 2720017

End: 2721084

Strand: Reverse

Name: nadA [H]

Synonym: Spea_2243

Alternate gene names: 157962064

Gene position: 2721084-2720017 (Counterclockwise)

Preceding gene: 157962065

Following gene: 157962063

Centisome position: 52.59

GC content: 45.41

Gene sequence:

>1068_bases
ATGAGCGCATTCGCCCCAATTATCGAAAATATTGATTACCCTTTTCCACCAAAGCCAGCTCCTTTATCTGAGCGAGAAAA
AGCCGAATCAAAAGCAAAAATTAAGCAGCTTTTAAAAGATAAAGATGCCGTGCTTGTGGCGCACTACTATACCGACCCAG
AGATCCAAGCCTTAGCCGAAGAAACGGGAGGCTGTGTTTCTGACTCGTTAGAGATGGCGCGTTTTGGTCGTGATCACCCA
GCAAAGACGTTAATCGTCGCTGGCGTTAAATTTATGGGCGAAACCGCAAAAATTTTAAGTCCTGAGAAGACTATCTTGAT
GCCGACGCTCGAAGCGACCTGTTCTTTAGATATAGGTTGCCCAATCGAGACATTCAGTGAGTTCTGCGATGCGCACCCAG
ATCACACGGTAGTCGTATATGCCAATACTTCAGCGGCGGTAAAAGCCAGAGCCGACTGGGTGGTTACATCGAGCATTGCC
CTTGAAATCGTTGAGCACCTAGACAGTGAAGATAAAAAGATTATCTGGGGACCAGATCGTCATTTAGGCAGCTATATCGC
CAAGCAAACCGGTGCCGAGATGTTGATGTGGCAAGGCGAATGTATCGTTCATGATGAATTCCAAGCCAAAGCTTTACGTG
AGCTGAAAAAGATCCATCCAAATGCCGCTGTACTGGTACATCCAGAATCTCCTGCAAGTGTGGTAGAGCTAGGCGATGCT
GTGGGCTCAACAAGCCAGCTGATTAAAGCGGCGCAAACCATGGATAATGATACTTTTATCGTGGCTACCGACAAAGGGAT
CTTCTATAAGATGCAGCAAGCTGCACCTAATAAAAATTTAATTGCCGCACCAACGGGTGGTAATGGAGCGACTTGTAAGA
GTTGTGCACATTGCCCATGGATGGCGATGAATGGCTTAAAAGCTATCGAGAGTGCGTTAGAAAACGTAGATGCGAGTCAT
CATGAGATATTTGTCGATGATAGTTTACGCTTAGATGCGTTAAAACCATTAGACAGAATGCTGAATTTTGCTCAGACACT
GAATATGAAAGTAAAAGGCAATGCGTAA

Upstream 100 bases:

>100_bases
AAATAGCGCCTTTTTTATTGGCAGCGTCGCTATAAGAGTTTTAAATTTGTGAAGTATTCCGTATAATTCCGCTAATCTGT
TATTGCCCGTTGGTTGTACT

Downstream 100 bases:

>100_bases
ATAGCTTAACTCTTATCATAGCCACCTACATTTAGTTGGCGCATTGAGTGACTATTATAGTTTAAAGAAAAAAAGCCCGT
TGATACGGGCTTTTTTTTCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSAFAPIIENIDYPFPPKPAPLSEREKAESKAKIKQLLKDKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDIGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEDKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKIHPNAAVLVHPESPASVVELGDA
VGSTSQLIKAAQTMDNDTFIVATDKGIFYKMQQAAPNKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENVDASH
HEIFVDDSLRLDALKPLDRMLNFAQTLNMKVKGNA

Sequences:

>Translated_355_residues
MSAFAPIIENIDYPFPPKPAPLSEREKAESKAKIKQLLKDKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHP
AKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDIGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIA
LEIVEHLDSEDKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKIHPNAAVLVHPESPASVVELGDA
VGSTSQLIKAAQTMDNDTFIVATDKGIFYKMQQAAPNKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENVDASH
HEIFVDDSLRLDALKPLDRMLNFAQTLNMKVKGNA
>Mature_354_residues
SAFAPIIENIDYPFPPKPAPLSEREKAESKAKIKQLLKDKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHPA
KTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDIGCPIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAL
EIVEHLDSEDKKIIWGPDRHLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKIHPNAAVLVHPESPASVVELGDAV
GSTSQLIKAAQTMDNDTFIVATDKGIFYKMQQAAPNKNLIAAPTGGNGATCKSCAHCPWMAMNGLKAIESALENVDASHH
EIFVDDSLRLDALKPLDRMLNFAQTLNMKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=336, Percent_Identity=71.1309523809524, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38625; Mature: 38493

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFAPIIENIDYPFPPKPAPLSEREKAESKAKIKQLLKDKDAVLVAHYYTDPEIQALAE
CCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDIGC
HHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCCEEEEEECCCEEEEECCC
PIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEDKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKIHPNAAVLVHPESPASVVELGDA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTMDNDTFIVATDKGIFYKMQQAAPNKNLIAAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEEHHCCCCCCEEEECCCCCCCCCHHHCCCCH
MAMNGLKAIESALENVDASHHEIFVDDSLRLDALKPLDRMLNFAQTLNMKVKGNA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCC
>Mature Secondary Structure 
SAFAPIIENIDYPFPPKPAPLSEREKAESKAKIKQLLKDKDAVLVAHYYTDPEIQALAE
CCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHH
ETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDIGC
HHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHHHHCCCCCEEEEEECCCEEEEECCC
PIETFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEDKKIIWGPDR
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHCCCCCCEEEECCCH
HLGSYIAKQTGAEMLMWQGECIVHDEFQAKALRELKKIHPNAAVLVHPESPASVVELGDA
HHHHHHHHHCCCCEEEECCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAAQTMDNDTFIVATDKGIFYKMQQAAPNKNLIAAPTGGNGATCKSCAHCPW
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEEHHCCCCCCEEEECCCCCCCCCHHHCCCCH
MAMNGLKAIESALENVDASHHEIFVDDSLRLDALKPLDRMLNFAQTLNMKVKGNA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]