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The map label for this gene is umuD [H]

Identifier: 157962017

GI number: 157962017

Start: 2665347

End: 2665754

Strand: Reverse

Name: umuD [H]

Synonym: Spea_2196

Alternate gene names: 157962017

Gene position: 2665754-2665347 (Counterclockwise)

Preceding gene: 157962023

Following gene: 157962016

Centisome position: 51.52

GC content: 44.36

Gene sequence:

>408_bases
ATGAACATTATCCCGATTGCAGCCAGTGCTGGCATTACAGGCTTTGAGTCCCCCGCTACCGATTACCGGCAACTGCCGTT
AAGTCTTGACGAGTTACTGATAGAACATCCGAGTTCAACGTTTATTGGCCAAGCCAATGGCGACTCTATGCAAGGTGTTG
GCATCTTTGATGGTGACATTTTAATTGTCGATAGGCATGTTGAGGTTCGCAATCAAGACGTGATAGTCGCCAACTACAAC
GGCTCGTTTGTTTGTAAGATTATCGATAAGGTAAATCGATTACTGCTATCCGCTAACGAATCCCACATGAGCACGCCCAT
TCTTGAACACGATACTTTTAGTGTTGAAGGCGTGGTTATACGTTCTATTCGCTGTCATCGTAGAAGCTCAATTTTAGAGA
ACGATTAA

Upstream 100 bases:

>100_bases
GAGAATGCTGCAAACTGCTCACAGATAGTTGTCATCCTTATTGCGCAAAATGATATAAAACCACTATACTGTATAAACAT
ACAGTTAATTATTTTTTAGC

Downstream 100 bases:

>100_bases
TCATGTATGCACTTGTGGATGCAAACTCATTTTATTGCAGCGCCGAGCAGGTATTTAGGCCTGACTGGCGTAACCGCCCT
ATCGTAGTGCTCAGTAACAA

Product: peptidase S24/S26 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MNIIPIAASAGITGFESPATDYRQLPLSLDELLIEHPSSTFIGQANGDSMQGVGIFDGDILIVDRHVEVRNQDVIVANYN
GSFVCKIIDKVNRLLLSANESHMSTPILEHDTFSVEGVVIRSIRCHRRSSILEND

Sequences:

>Translated_135_residues
MNIIPIAASAGITGFESPATDYRQLPLSLDELLIEHPSSTFIGQANGDSMQGVGIFDGDILIVDRHVEVRNQDVIVANYN
GSFVCKIIDKVNRLLLSANESHMSTPILEHDTFSVEGVVIRSIRCHRRSSILEND
>Mature_135_residues
MNIIPIAASAGITGFESPATDYRQLPLSLDELLIEHPSSTFIGQANGDSMQGVGIFDGDILIVDRHVEVRNQDVIVANYN
GSFVCKIIDKVNRLLLSANESHMSTPILEHDTFSVEGVVIRSIRCHRRSSILEND

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=115, Percent_Identity=39.1304347826087, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 14848; Mature: 14848

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIPIAASAGITGFESPATDYRQLPLSLDELLIEHPSSTFIGQANGDSMQGVGIFDGDI
CCEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCEEECCCCCCCCCEEEECCCE
LIVDRHVEVRNQDVIVANYNGSFVCKIIDKVNRLLLSANESHMSTPILEHDTFSVEGVVI
EEEECEEEECCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEE
RSIRCHRRSSILEND
EEEHHHHHCCCCCCC
>Mature Secondary Structure
MNIIPIAASAGITGFESPATDYRQLPLSLDELLIEHPSSTFIGQANGDSMQGVGIFDGDI
CCEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCEEECCCCCCCCCEEEECCCE
LIVDRHVEVRNQDVIVANYNGSFVCKIIDKVNRLLLSANESHMSTPILEHDTFSVEGVVI
EEEECEEEECCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEE
RSIRCHRRSSILEND
EEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]