Click here to switch to the map view.

The map label for this gene is codA [H]

Identifier: 157962008

GI number: 157962008

Start: 2651397

End: 2652692

Strand: Reverse

Name: codA [H]

Synonym: Spea_2187

Alternate gene names: 157962008

Gene position: 2652692-2651397 (Counterclockwise)

Preceding gene: 157962009

Following gene: 157962006

Centisome position: 51.26

GC content: 46.76

Gene sequence:

>1296_bases
ATGTCATCAGCAAGTATGTTGATCAAAAATGTGACTCTAAAAGGTCAAGAAGGCCTTCAACAATTGTTGATTGAAGACGG
TAAGTTCAAAGCGATTGCTGCTATGAGCCAAAGCATCGAACTTCCAAGTGCCGATTCTTTACAAGTGATTGATGGTGAAG
GCGGCATGGCTGTGCCACCTTTTTGTGAGCCACATGTTCACTTAGATACCACGCAAACTGCTGGCGAGCCGAGCTGGAAC
ATTTCAGGCACCTTGTTTGAAGGGATCGAACGCTGGTCTGAGCGTAAATCCATGCTGTCTATCGAAGACGTTAAGTCTCG
TGCTAAGCAAACCCTAAAATGGCAGATTGCCAACGGTATCCAGCACGTTCGTACTCACGTCGATGTATCGGATCCGACTC
TAATTGCACTTAAAGCCATGCTTGAAGTGAAAGAAGAGATGAAGCCTTGGGTGGATATCCAGATTGTGGCTTTCCCGCAA
GAAGGTATTCTGTCTTACCCTAACGGTAAAGAGCTACTAGAAGAAGCGGTAAAGCTAGGCGCAGATGTGATTGGCGCGAT
CCCGCACTTTGAATTTACCCGTGAATACGGCGTAGAGTCGCTACATTATGTGTTTGATCTTGCTCGTAAGTACGACCGCC
TAATCGACGTTCACTGTGATGAAATTGATGATGAGCAGTCTCGCTTTGTAGAAACGGTTGCAGCTCTTGCACATAAGTAT
CAAATGGGCGAGCGCGTAACAGCGAGTCACACAACGGCAATGCACTCTTACAATGGTGCATATGCTTCACGTCTGTTCCG
TCTACTTGGCATGTCAGGGATTAACTTCGTTGCCAACCCGCTAGTGAATATCCATCTACAGGGCCGTTTCGATGATTATC
CTAAGCGCCGTGGTATTACCCGCGTGAAAGAGATGCTAGCTGCTGACATTAACGTCTGTTTTGGTCACGATGATATTTTC
GACCCTTGGTATCCACTAGGTACAGCTAACATGCTGCAGGTGCTGCACATGGGGCTACATGTTTGCCAAATCATGGGTTA
CGATCAAATCAACAACTCGCTAGAGCTTATCACCAACAAGTCAGCACGCACGCTAAACATCCAAGACACCTATGGTATTG
AGCTAGGTAAACCAGGTAACTTGCTTATCTTGCCTGCCGATAATGGCTTTGATGCGCTACGTCGTCAGGTTCCAGTACGT
TACTCTGTGCGTCAGGGTAAGGTGTTAGCTGAGACTCAGGTTGCACAAACACAAATTCACTTGAATGAAACCGAAGAAGT
GACCTTCCGTCGTTAA

Upstream 100 bases:

>100_bases
ATCAGCTATTTATTAATAGATGAAGCGCTAAAACGCATGAATAAACAAAAATTAGTTAAATCAGATTGTAAAAATGCTAC
CAATGCATAAGGAAAACACC

Downstream 100 bases:

>100_bases
AACAACTTGCTTAAAAGGCTAATAGCTTAAGAAAAGTGGTAAATTTATTTGTGCTCAGTAAAACTTGCAGCGTAGATAGG
CTTACCACTTTTGATTAAAA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSSASMLIKNVTLKGQEGLQQLLIEDGKFKAIAAMSQSIELPSADSLQVIDGEGGMAVPPFCEPHVHLDTTQTAGEPSWN
ISGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKPWVDIQIVAFPQ
EGILSYPNGKELLEEAVKLGADVIGAIPHFEFTREYGVESLHYVFDLARKYDRLIDVHCDEIDDEQSRFVETVAALAHKY
QMGERVTASHTTAMHSYNGAYASRLFRLLGMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLAADINVCFGHDDIF
DPWYPLGTANMLQVLHMGLHVCQIMGYDQINNSLELITNKSARTLNIQDTYGIELGKPGNLLILPADNGFDALRRQVPVR
YSVRQGKVLAETQVAQTQIHLNETEEVTFRR

Sequences:

>Translated_431_residues
MSSASMLIKNVTLKGQEGLQQLLIEDGKFKAIAAMSQSIELPSADSLQVIDGEGGMAVPPFCEPHVHLDTTQTAGEPSWN
ISGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKPWVDIQIVAFPQ
EGILSYPNGKELLEEAVKLGADVIGAIPHFEFTREYGVESLHYVFDLARKYDRLIDVHCDEIDDEQSRFVETVAALAHKY
QMGERVTASHTTAMHSYNGAYASRLFRLLGMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLAADINVCFGHDDIF
DPWYPLGTANMLQVLHMGLHVCQIMGYDQINNSLELITNKSARTLNIQDTYGIELGKPGNLLILPADNGFDALRRQVPVR
YSVRQGKVLAETQVAQTQIHLNETEEVTFRR
>Mature_430_residues
SSASMLIKNVTLKGQEGLQQLLIEDGKFKAIAAMSQSIELPSADSLQVIDGEGGMAVPPFCEPHVHLDTTQTAGEPSWNI
SGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGIQHVRTHVDVSDPTLIALKAMLEVKEEMKPWVDIQIVAFPQE
GILSYPNGKELLEEAVKLGADVIGAIPHFEFTREYGVESLHYVFDLARKYDRLIDVHCDEIDDEQSRFVETVAALAHKYQ
MGERVTASHTTAMHSYNGAYASRLFRLLGMSGINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLAADINVCFGHDDIFD
PWYPLGTANMLQVLHMGLHVCQIMGYDQINNSLELITNKSARTLNIQDTYGIELGKPGNLLILPADNGFDALRRQVPVRY
SVRQGKVLAETQVAQTQIHLNETEEVTFRR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=430, Percent_Identity=75.1162790697674, Blast_Score=675, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=336, Percent_Identity=24.4047619047619, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 48360; Mature: 48229

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASMLIKNVTLKGQEGLQQLLIEDGKFKAIAAMSQSIELPSADSLQVIDGEGGMAVPP
CCCHHEEHHHEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEECCC
FCEPHVHLDTTQTAGEPSWNISGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGI
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QHVRTHVDVSDPTLIALKAMLEVKEEMKPWVDIQIVAFPQEGILSYPNGKELLEEAVKLG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
ADVIGAIPHFEFTREYGVESLHYVFDLARKYDRLIDVHCDEIDDEQSRFVETVAALAHKY
HHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
QMGERVTASHTTAMHSYNGAYASRLFRLLGMSGINFVANPLVNIHLQGRFDDYPKRRGIT
HCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCHHHCCHH
RVKEMLAADINVCFGHDDIFDPWYPLGTANMLQVLHMGLHVCQIMGYDQINNSLELITNK
HHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEECC
SARTLNIQDTYGIELGKPGNLLILPADNGFDALRRQVPVRYSVRQGKVLAETQVAQTQIH
CCEEEEECCCCCEEECCCCCEEEEECCCCHHHHHHCCCCEEECCCCCEEHHHHHHHHEEE
LNETEEVTFRR
ECCCCCCCCCC
>Mature Secondary Structure 
SSASMLIKNVTLKGQEGLQQLLIEDGKFKAIAAMSQSIELPSADSLQVIDGEGGMAVPP
CCHHEEHHHEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEECCC
FCEPHVHLDTTQTAGEPSWNISGTLFEGIERWSERKSMLSIEDVKSRAKQTLKWQIANGI
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QHVRTHVDVSDPTLIALKAMLEVKEEMKPWVDIQIVAFPQEGILSYPNGKELLEEAVKLG
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
ADVIGAIPHFEFTREYGVESLHYVFDLARKYDRLIDVHCDEIDDEQSRFVETVAALAHKY
HHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
QMGERVTASHTTAMHSYNGAYASRLFRLLGMSGINFVANPLVNIHLQGRFDDYPKRRGIT
HCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCHHHCCHH
RVKEMLAADINVCFGHDDIFDPWYPLGTANMLQVLHMGLHVCQIMGYDQINNSLELITNK
HHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEECC
SARTLNIQDTYGIELGKPGNLLILPADNGFDALRRQVPVRYSVRQGKVLAETQVAQTQIH
CCEEEEECCCCCEEECCCCCEEEEECCCCHHHHHHCCCCEEECCCCCEEHHHHHHHHEEE
LNETEEVTFRR
ECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]