Click here to switch to the map view.

The map label for this gene is caiD [C]

Identifier: 157961979

GI number: 157961979

Start: 2612196

End: 2612981

Strand: Direct

Name: caiD [C]

Synonym: Spea_2158

Alternate gene names: 157961979

Gene position: 2612196-2612981 (Clockwise)

Preceding gene: 157961978

Following gene: 157961980

Centisome position: 50.48

GC content: 47.58

Gene sequence:

>786_bases
ATGGCCAATGCATCGGTTAACCCTATTTCGCTGCCTAAATCAGCATTTATTACAGAGCTAAAAAATGGCGTCGCGGAGTT
GGTGATCAACAAACCGCCAGTCAATGCCTTAGATAGCCATGAATGGTTCGCCTTAGCTCATGAGATTGAACGACTCAACG
CGGATCTAGCCGTTAGAGTGATTGTTATTCGTGCTGAAGGTCGAGGCTTTTGTGCCGGCGTTGACATTAAAGAACTGGAT
CAGTACCCAGAACGCATTGTTGCCGTAAATGCCGGTAATTATGCGACGTTTAAAGCCATTCATCGGGCAACAGTGCCGGT
AATTGTCGCCGTTCATGGATTTGTACTGGGCGGTGGAATTGGTATCACAGGTGCTGCAGATATTGTAGTTGCATCCGATT
GTGCCACATTTGCACTACCAGAGGTGGATCGCGGCGCAATGGGCGGTGGAGCCCATTTACAAAGATTGTTCCCGGTACAG
AAAGTACGCTACATGTTTTTTACTGGTGACACTATCACGGCACCAGATGCAGAGCGCTATGGCTTTATTGAGCGCATCGT
TACTAAGCAAGAGCTGCGTAAAACGGCGTTAGCTATTGCCACTAAAATCGCGGCGAAAAGTCCTGAAATGATCCGTATTG
CCAAAGAAGCCTTAAATGGTATTGAAGATGGCAATCTCGAAGACAAATACCGCTGGGAGCAAGGTTTCACACTGCAGGCC
TATACCTCTCCAGACTCAGCTGAAACTCGTAAGGCGTTTATCGAAAAGCGTGAAGCGAGCTTTTAG

Upstream 100 bases:

>100_bases
TAAAACAAGCACATCAATGCTTAAGCCAACTTCAGGCTCGAACATTAATTACCGAGACACCAATCAATAAAAATCACTCT
ACAAAGGAGGCTAGCTAATT

Downstream 100 bases:

>100_bases
TTTTAACCCTTTACCATTCGAGGCAGCTTATGAATTTAACATATACAAAACAACAACAAGCGTTTCGGTTAGAAGTACGC
CAATGGTTAGCGGATAACTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MANASVNPISLPKSAFITELKNGVAELVINKPPVNALDSHEWFALAHEIERLNADLAVRVIVIRAEGRGFCAGVDIKELD
QYPERIVAVNAGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQ
KVRYMFFTGDTITAPDAERYGFIERIVTKQELRKTALAIATKIAAKSPEMIRIAKEALNGIEDGNLEDKYRWEQGFTLQA
YTSPDSAETRKAFIEKREASF

Sequences:

>Translated_261_residues
MANASVNPISLPKSAFITELKNGVAELVINKPPVNALDSHEWFALAHEIERLNADLAVRVIVIRAEGRGFCAGVDIKELD
QYPERIVAVNAGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQ
KVRYMFFTGDTITAPDAERYGFIERIVTKQELRKTALAIATKIAAKSPEMIRIAKEALNGIEDGNLEDKYRWEQGFTLQA
YTSPDSAETRKAFIEKREASF
>Mature_260_residues
ANASVNPISLPKSAFITELKNGVAELVINKPPVNALDSHEWFALAHEIERLNADLAVRVIVIRAEGRGFCAGVDIKELDQ
YPERIVAVNAGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQK
VRYMFFTGDTITAPDAERYGFIERIVTKQELRKTALAIATKIAAKSPEMIRIAKEALNGIEDGNLEDKYRWEQGFTLQAY
TSPDSAETRKAFIEKREASF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=30.4, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI31542718, Length=242, Percent_Identity=28.5123966942149, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI70995211, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594469, Length=253, Percent_Identity=27.6679841897233, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI37594471, Length=253, Percent_Identity=27.6679841897233, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4502327, Length=274, Percent_Identity=27.3722627737226, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=31.1740890688259, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=32.5581395348837, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082183, Length=211, Percent_Identity=28.9099526066351, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=25.2918287937743, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=31.0204081632653, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=29.2, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=281, Percent_Identity=28.1138790035587, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=25.8964143426295, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=204, Percent_Identity=30.3921568627451, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=27.4900398406374, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=215, Percent_Identity=24.6511627906977, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129971, Length=256, Percent_Identity=30.859375, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24653477, Length=256, Percent_Identity=30.859375, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI19920382, Length=252, Percent_Identity=29.3650793650794, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28400; Mature: 28269

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANASVNPISLPKSAFITELKNGVAELVINKPPVNALDSHEWFALAHEIERLNADLAVRV
CCCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
IVIRAEGRGFCAGVDIKELDQYPERIVAVNAGNYATFKAIHRATVPVIVAVHGFVLGGGI
EEEEECCCCEEECCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQKVRYMFFTGDTITAPDAERY
CCCCCCEEEEECCCHHHCCCCCCCCCCCCCHHHHHHCCHHHEEEEEEECCEECCCCHHHH
GFIERIVTKQELRKTALAIATKIAAKSPEMIRIAKEALNGIEDGNLEDKYRWEQGFTLQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEE
YTSPDSAETRKAFIEKREASF
ECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANASVNPISLPKSAFITELKNGVAELVINKPPVNALDSHEWFALAHEIERLNADLAVRV
CCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
IVIRAEGRGFCAGVDIKELDQYPERIVAVNAGNYATFKAIHRATVPVIVAVHGFVLGGGI
EEEEECCCCEEECCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQKVRYMFFTGDTITAPDAERY
CCCCCCEEEEECCCHHHCCCCCCCCCCCCCHHHHHHCCHHHEEEEEEECCEECCCCHHHH
GFIERIVTKQELRKTALAIATKIAAKSPEMIRIAKEALNGIEDGNLEDKYRWEQGFTLQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEE
YTSPDSAETRKAFIEKREASF
ECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA