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The map label for this gene is atoD [C]

Identifier: 157961975

GI number: 157961975

Start: 2608306

End: 2609181

Strand: Direct

Name: atoD [C]

Synonym: Spea_2154

Alternate gene names: 157961975

Gene position: 2608306-2609181 (Clockwise)

Preceding gene: 157961974

Following gene: 157961976

Centisome position: 50.41

GC content: 46.69

Gene sequence:

>876_bases
ATGAATAAATTACAAACCGTAAAGCAAATGGTCGAACAGCTCGAAGACGGCATGACTATCGGTATCGGTGGTTGGGGACC
AAGACGAAAGCCGATGGCGCTAATTCGCGAGATCCTTCGCTCAGACTTAAAAGATCTCACCATTGTTGCCTATGGCGGTG
CAGACGTTGGCATGCTTTGCGCTGCCAATAAAGTAAAGAAAGTTATCTTCGCATTTGTATCTCTTGATTTTATTCCCCTC
GAGCCCTTTTTCAGAAAGGCTCGTCAAAATGGTGACATCGACATCATGGAAATTGATGAGGGAATGATGTTGCTCGGCTT
ACGGGCTGCAGCATGGGGTTGCCCATTTATACCGACTCAAGTCGGCTTAGGTACCGATGTCGTTAAGGTTAATCCGGACT
TAAAAGTCATTGATAGCCCCTATGACGATAAAGAGTGGGTAGCCATGCCAGCATTGAAGCTCGACGCGGCACTGATCCAT
GTCGATAGAGCCGATGTTCGCGGTGTGTGTCAAATCACTGGACCCGATCACTATATGGATGATTGGTTTGTTAGAGCGGC
TAAAAAAGCCTTGGTGACCTGCGATGAACTTGTGGGATCTGAAGTATTTAACGACCCTAATGCAGCACGCTGTGTTTTTT
GGGAGCGTAGCCTAACAACCGCAGTCGCCCATGTCCCCGCGGGTGCTCATCCAACCTCTTGCGCGCCTTTTTACGGTTTT
GATACCGCCCATTTTAAAGAATACAACGCTTGTGCGCGTGACGGTGGTTTTGAACTGTATTTCGATAAATATGTAAAAGA
TAAGTGTGAAAATGATTATCAAGCGTTAGTCGGCGGGGTAGACACCATAAAACAATTAGCCTTACCGGTTTACTAA

Upstream 100 bases:

>100_bases
GCAAGTTGATTGGCAGGACCATTGCGCCTTTGAGTTTACTCGAGTGAGCATTTGGGGCCACGATTTTTCAGTTGGACAAA
ATCAACAAGGAGCCGAGTAG

Downstream 100 bases:

>100_bases
ACATATCAACGACAGCAGCGCCTTGAATACATTGCGAGGCGGTCAAATTTTGCAGCAAGGAAAAGGATAACACGATGACT
ATAGCGAAAGAGTACAGCTT

Product: coenzyme A transferase

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNKLQTVKQMVEQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKALVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKDKCENDYQALVGGVDTIKQLALPVY

Sequences:

>Translated_291_residues
MNKLQTVKQMVEQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKALVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKDKCENDYQALVGGVDTIKQLALPVY
>Mature_291_residues
MNKLQTVKQMVEQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKALVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKDKCENDYQALVGGVDTIKQLALPVY

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552 [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Escherichia coli, GI1788551, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 32218; Mature: 32218

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLQTVKQMVEQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLC
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AANKVKKVIFAFVSLDFIPLEPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQ
HHHHHHHHHHHHHHCCCEECCHHHHHHHCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCC
VGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIHVDRADVRGVCQITGPDHYMD
CCCCCCEEEECCCCEEECCCCCCCCEEECCHHHHCEEEEEECCCCCCEEEEECCCCCHHH
DWFVRAAKKALVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
DTAHFKEYNACARDGGFELYFDKYVKDKCENDYQALVGGVDTIKQLALPVY
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MNKLQTVKQMVEQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLC
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AANKVKKVIFAFVSLDFIPLEPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQ
HHHHHHHHHHHHHHCCCEECCHHHHHHHCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCC
VGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIHVDRADVRGVCQITGPDHYMD
CCCCCCEEEECCCCEEECCCCCCCCEEECCHHHHCEEEEEECCCCCCEEEEECCCCCHHH
DWFVRAAKKALVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
DTAHFKEYNACARDGGFELYFDKYVKDKCENDYQALVGGVDTIKQLALPVY
CHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]