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The map label for this gene is 157961946

Identifier: 157961946

GI number: 157961946

Start: 2572035

End: 2573798

Strand: Direct

Name: 157961946

Synonym: Spea_2125

Alternate gene names: NA

Gene position: 2572035-2573798 (Clockwise)

Preceding gene: 157961945

Following gene: 157961947

Centisome position: 49.71

GC content: 45.35

Gene sequence:

>1764_bases
ATGACATTCAGTGCCTTAGATAAACCTACAAATGACAACCAAACCACTTTCGACATCATTATCGTTGGCTCTGGAGCTGG
GGCAATGGCTTCATCTATTGTTGCCTCTGATCATGGCTTATCAGTATTAGTGGTTGAAAAGTCGGGTAAGTTTGGCGGAA
CTTCAGCACTTTCTGGTGGTGGAATTTGGATCCCCAATAATGATCACTTCAAGGCAAAAGGTGGCCAGGACAGTTATCAA
CAAGCATTTGATTACCTAAAAGCGTCTACCGAGAACAGAGTGTCAGACTCTAGATTACATGCCTACTTAACTCATGCTCC
AGAAATGATCCGATATTTAGAGCGCAAAAGCCGCGTACGCTACGCCGTTGCCGAAAAATACCCAGATTATTATCCTCATC
TTGAAGGATCGTTGGCTGGTGGGCGTACTCTTGATCCTGAAATATTTGATACCACATGCATGGGCGATGAGGTTGAAAAC
CAGTTAAAGGCTTCAGCGTCTACGCTATTGATGGGAAAAATTGCGTGGACTGCCCGCGATGCTCATAAAGCGATGGCCCG
TGAGCGCGGCTGGCGATTATTACTGTTAAAGCTGATCATGAAATATAAGCTTGATTTTGGTCAACGCCGTAAAACTCGGC
GCGATAGACGGGCAGCGTTAGGCAGCTCATTAGTTGCTTCACTTAGGCAGTCAATGACAGATCGGAATATTCCGCTTTGG
CTTGATACAGACTTTACCGATATCGTGTTTAGTCAAGATAGAGTTTGTGGAATTGAAGTCGTCCGTGATGGTGAAAAACA
AACACTTAACGCAAAGCTAGCGGTGATTTTTGCAAGTGGGGGGTTTGAGCAAAATCAGAAGCTTAGGGATAAGTATCTGC
CGAGCCCATCAAATGTTAAGTGGAGCGCAACGCCTCCAGGTAATAACACTGGCGCGGCTTTAGAAGCAGGGATCCGTGCT
GGTGCAAACACAGATATCATGGATTGGTGTTGGTGGTCACCTACAGTGAAGGTGCCTAAAGAAGATAAAGCAAGAGGCCT
TTTTGCTGAACGTGCTTTTCCCGGTGCAATTGTCGTTGATGGCTTGGGCAAGCGCTTTGTTAATGAGGCCGCTCCTTACC
TAGAGTTTGGTGATGCAATGTATCGAAATAATGCGGCAACAGACGGTAAGTCTCTACCTGCATGGGTGATATTCGATGCA
AACTTTAGGTTTAACTACGCCATGGGGCCTTTTATGCCGGCACAAATTCAGCCCGATAGTCGATTACCTAAAGGCTGGTT
AAATACCCTTTATTGGAAGGCTGATAGTCTCGATGAATTGGCCAAACAGATTAAAATAGATGCCGATGGACTTTCACATA
CTGTAGAGCGGATCAATCGGTTTGCAACAACTGGGGTTGATGAAGATTTTGGCCGAGGGAGTAATGTTTTCGACCGCTAT
TATGGTGACACCAATGTTAAACCTAACCCTTGTTTAGCACCAATAGTTAAGGGGCCTTTTTATGCTATGCGAATTGAAGC
GGGGGATATTGGAACTAAAGGGGGTTTGCTAACCAATGAGCATGCTCAGGTAATGAATACAGACAACATGCCGATTGCTG
GACTCTACGCTATCGGTAACTGTTCAGCTTCTGTAATGGGTCAAAGTTATCCAGGTGCTGGAGCAACGTTAGGCCCTGCT
ATGACCTTTGGCTATATCGCCGCAAATCATATAGCAAAGGACATTACAAAGGACCTGACTAATGGCAAACAAACTACTCT
CTAG

Upstream 100 bases:

>100_bases
CCAAATTTAGTGGATTGTGTATTCCACTAGTTAACACGCTTCTTGCTGATACCGAGCAGGGAGTACTGGTAATCATTAGT
TCACAATAGTGAGATAGCAA

Downstream 100 bases:

>100_bases
CATTGAACAGGCTTTTACTCTGCTGTTATTTTGCCACTCTGACGAAGCATATTGTATATACAGTTGTGATTCGTTAATTG
AAGGTATGCGTGCTTGGCCT

Product: fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MTFSALDKPTNDNQTTFDIIIVGSGAGAMASSIVASDHGLSVLVVEKSGKFGGTSALSGGGIWIPNNDHFKAKGGQDSYQ
QAFDYLKASTENRVSDSRLHAYLTHAPEMIRYLERKSRVRYAVAEKYPDYYPHLEGSLAGGRTLDPEIFDTTCMGDEVEN
QLKASASTLLMGKIAWTARDAHKAMARERGWRLLLLKLIMKYKLDFGQRRKTRRDRRAALGSSLVASLRQSMTDRNIPLW
LDTDFTDIVFSQDRVCGIEVVRDGEKQTLNAKLAVIFASGGFEQNQKLRDKYLPSPSNVKWSATPPGNNTGAALEAGIRA
GANTDIMDWCWWSPTVKVPKEDKARGLFAERAFPGAIVVDGLGKRFVNEAAPYLEFGDAMYRNNAATDGKSLPAWVIFDA
NFRFNYAMGPFMPAQIQPDSRLPKGWLNTLYWKADSLDELAKQIKIDADGLSHTVERINRFATTGVDEDFGRGSNVFDRY
YGDTNVKPNPCLAPIVKGPFYAMRIEAGDIGTKGGLLTNEHAQVMNTDNMPIAGLYAIGNCSASVMGQSYPGAGATLGPA
MTFGYIAANHIAKDITKDLTNGKQTTL

Sequences:

>Translated_587_residues
MTFSALDKPTNDNQTTFDIIIVGSGAGAMASSIVASDHGLSVLVVEKSGKFGGTSALSGGGIWIPNNDHFKAKGGQDSYQ
QAFDYLKASTENRVSDSRLHAYLTHAPEMIRYLERKSRVRYAVAEKYPDYYPHLEGSLAGGRTLDPEIFDTTCMGDEVEN
QLKASASTLLMGKIAWTARDAHKAMARERGWRLLLLKLIMKYKLDFGQRRKTRRDRRAALGSSLVASLRQSMTDRNIPLW
LDTDFTDIVFSQDRVCGIEVVRDGEKQTLNAKLAVIFASGGFEQNQKLRDKYLPSPSNVKWSATPPGNNTGAALEAGIRA
GANTDIMDWCWWSPTVKVPKEDKARGLFAERAFPGAIVVDGLGKRFVNEAAPYLEFGDAMYRNNAATDGKSLPAWVIFDA
NFRFNYAMGPFMPAQIQPDSRLPKGWLNTLYWKADSLDELAKQIKIDADGLSHTVERINRFATTGVDEDFGRGSNVFDRY
YGDTNVKPNPCLAPIVKGPFYAMRIEAGDIGTKGGLLTNEHAQVMNTDNMPIAGLYAIGNCSASVMGQSYPGAGATLGPA
MTFGYIAANHIAKDITKDLTNGKQTTL
>Mature_586_residues
TFSALDKPTNDNQTTFDIIIVGSGAGAMASSIVASDHGLSVLVVEKSGKFGGTSALSGGGIWIPNNDHFKAKGGQDSYQQ
AFDYLKASTENRVSDSRLHAYLTHAPEMIRYLERKSRVRYAVAEKYPDYYPHLEGSLAGGRTLDPEIFDTTCMGDEVENQ
LKASASTLLMGKIAWTARDAHKAMARERGWRLLLLKLIMKYKLDFGQRRKTRRDRRAALGSSLVASLRQSMTDRNIPLWL
DTDFTDIVFSQDRVCGIEVVRDGEKQTLNAKLAVIFASGGFEQNQKLRDKYLPSPSNVKWSATPPGNNTGAALEAGIRAG
ANTDIMDWCWWSPTVKVPKEDKARGLFAERAFPGAIVVDGLGKRFVNEAAPYLEFGDAMYRNNAATDGKSLPAWVIFDAN
FRFNYAMGPFMPAQIQPDSRLPKGWLNTLYWKADSLDELAKQIKIDADGLSHTVERINRFATTGVDEDFGRGSNVFDRYY
GDTNVKPNPCLAPIVKGPFYAMRIEAGDIGTKGGLLTNEHAQVMNTDNMPIAGLYAIGNCSASVMGQSYPGAGATLGPAM
TFGYIAANHIAKDITKDLTNGKQTTL

Specific function: Dehydrogenates steroids by introducing a double bond in steroid ring A (Probable) [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 64387; Mature: 64255

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSALDKPTNDNQTTFDIIIVGSGAGAMASSIVASDHGLSVLVVEKSGKFGGTSALSGG
CCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
GIWIPNNDHFKAKGGQDSYQQAFDYLKASTENRVSDSRLHAYLTHAPEMIRYLERKSRVR
EEECCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAVAEKYPDYYPHLEGSLAGGRTLDPEIFDTTCMGDEVENQLKASASTLLMGKIAWTARD
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHH
AHKAMARERGWRLLLLKLIMKYKLDFGQRRKTRRDRRAALGSSLVASLRQSMTDRNIPLW
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LDTDFTDIVFSQDRVCGIEVVRDGEKQTLNAKLAVIFASGGFEQNQKLRDKYLPSPSNVK
ECCCCHHEEECCCCEEEEEEEECCCCCEECEEEEEEEECCCCCCCHHHHHHCCCCCCCEE
WSATPPGNNTGAALEAGIRAGANTDIMDWCWWSPTVKVPKEDKARGLFAERAFPGAIVVD
EECCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCCHHHHCCCCEEEEC
GLGKRFVNEAAPYLEFGDAMYRNNAATDGKSLPAWVIFDANFRFNYAMGPFMPAQIQPDS
CHHHHHHHHCCCHHHHCHHHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCC
RLPKGWLNTLYWKADSLDELAKQIKIDADGLSHTVERINRFATTGVDEDFGRGSNVFDRY
CCCHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHH
YGDTNVKPNPCLAPIVKGPFYAMRIEAGDIGTKGGLLTNEHAQVMNTDNMPIAGLYAIGN
CCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCCCCEEECCCHHEECCCCCCEEEEEEECC
CSASVMGQSYPGAGATLGPAMTFGYIAANHIAKDITKDLTNGKQTTL
CCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TFSALDKPTNDNQTTFDIIIVGSGAGAMASSIVASDHGLSVLVVEKSGKFGGTSALSGG
CCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
GIWIPNNDHFKAKGGQDSYQQAFDYLKASTENRVSDSRLHAYLTHAPEMIRYLERKSRVR
EEECCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAVAEKYPDYYPHLEGSLAGGRTLDPEIFDTTCMGDEVENQLKASASTLLMGKIAWTARD
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHH
AHKAMARERGWRLLLLKLIMKYKLDFGQRRKTRRDRRAALGSSLVASLRQSMTDRNIPLW
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LDTDFTDIVFSQDRVCGIEVVRDGEKQTLNAKLAVIFASGGFEQNQKLRDKYLPSPSNVK
ECCCCHHEEECCCCEEEEEEEECCCCCEECEEEEEEEECCCCCCCHHHHHHCCCCCCCEE
WSATPPGNNTGAALEAGIRAGANTDIMDWCWWSPTVKVPKEDKARGLFAERAFPGAIVVD
EECCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCCHHHHCCCCEEEEC
GLGKRFVNEAAPYLEFGDAMYRNNAATDGKSLPAWVIFDANFRFNYAMGPFMPAQIQPDS
CHHHHHHHHCCCHHHHCHHHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCCCC
RLPKGWLNTLYWKADSLDELAKQIKIDADGLSHTVERINRFATTGVDEDFGRGSNVFDRY
CCCHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHH
YGDTNVKPNPCLAPIVKGPFYAMRIEAGDIGTKGGLLTNEHAQVMNTDNMPIAGLYAIGN
CCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCCCCEEECCCHHEECCCCCCEEEEEEECC
CSASVMGQSYPGAGATLGPAMTFGYIAANHIAKDITKDLTNGKQTTL
CCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1657885 [H]