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The map label for this gene is mhpF [C]

Identifier: 157961938

GI number: 157961938

Start: 2561614

End: 2562537

Strand: Reverse

Name: mhpF [C]

Synonym: Spea_2117

Alternate gene names: 157961938

Gene position: 2562537-2561614 (Counterclockwise)

Preceding gene: 157961939

Following gene: 157961937

Centisome position: 49.52

GC content: 44.59

Gene sequence:

>924_bases
ATGACAAGTAAAATAAAATGTGCGCTGATTGGCTCTGGCAATATTGGCACCGACCTACTGTACAAATTACTGCGAAGTGA
TGTGCTTGAGCCGGTGTGGATGGTAGGAATAGACCCAGACTCTGACGGTTTAGCTAAAGCTAAAGCTGCTGGGCTAAAAG
TAACCGCTGATGGTATAGATGGTTTACTTCCCTTTGTTGAAGCCGATGAGATAAAAATTGCTTTCGATGCGACATCAGCT
TATGTGCATGCAGAAAATTCAAGAAAACTAAATGAATTAGGGGTGGTGATGATTGATTTAACCCCAGCTGCAATTGGTCC
CTTTTGCGTACCGCCAGTCAACCTTGAGCAACTTGATGAAAATATTAACAACATTAATATGGTCACCTGTGGTGGACAAG
CAACTATTCCTATGGTTGCAGCGGTGTCACAAGTACAGGCTGTAGAGTACGGTGAAATTGTTGCCACGGTATCTTCGCGC
TCCGTGGGTCCGGGAACGAGGCAAAACATTGATGAATTTACCCGTACCACAGCTGGTGCAGTTGAACAAATTGGCGGTGC
AGAAAAAGGCAAAGCTATTATTGTCATTAACCCTGCTGAGCCACCGTTACTGATGCGCGATACCATTCATTGTCTAACAA
AAGATCAACCCGATGAACAGGCGATTACTGCATCTGTTCATAAGATGATTGAACAAGTTCAACAATATGTACCCGGTTAC
ACCCTTAAAAACGGTCCGGTGTTTGATGGTCGTAAGGTCACTATCTTTTTAGAAGTCGAAGGGCTGGGCGATTACTTACC
AAAGTATGCCGGTAACCTAGACATAATGACCGCTGCAGCAGCCAGAACAGCAGAAATGCTAGCGTCCAAAATGCTCAATG
TTAAAACCCATCTTAACGTTACCAAAGAAGCGGCGCTAGCCTAG

Upstream 100 bases:

>100_bases
TTCACCATGGAAATCGAAGGTTTGGGAAGCTGCAGCATCAGTTTTTGTGATTAATGCAATCTCAACTCTCAGCACGGAAA
TAATACAAAGGAAAACCGAC

Downstream 100 bases:

>100_bases
GAGATCACGATGAACTTAACTGGAAAAAAAGTTATCTTACACGATATGTCATTAAGAGACGGCATGCATGCTCGCCAACA
CCAAATTAGTTTGAAAGAGA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGIDGLLPFVEADEIKIAFDATSA
YVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDENINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSR
SVGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGY
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNVTKEAALA

Sequences:

>Translated_307_residues
MTSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGIDGLLPFVEADEIKIAFDATSA
YVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDENINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSR
SVGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGY
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNVTKEAALA
>Mature_306_residues
TSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGIDGLLPFVEADEIKIAFDATSAY
VHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDENINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSRS
VGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGYT
LKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNVTKEAALA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=309, Percent_Identity=55.663430420712, Blast_Score=317, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 32661; Mature: 32530

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGID
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCEEEEECCCC
GLLPFVEADEIKIAFDATSAYVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDE
CCCCCCCCCCEEEEEECCEEEEEECCCCCHHHCCEEEEEECHHHCCCCCCCCCCHHHHHC
NINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSRSVGPGTRQNIDEFTRTTAGA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
VEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGY
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNV
EECCCCEECCEEEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
TKEAALA
HHHHHCC
>Mature Secondary Structure 
TSKIKCALIGSGNIGTDLLYKLLRSDVLEPVWMVGIDPDSDGLAKAKAAGLKVTADGID
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCEEEEECCCC
GLLPFVEADEIKIAFDATSAYVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLEQLDE
CCCCCCCCCCEEEEEECCEEEEEECCCCCHHHCCEEEEEECHHHCCCCCCCCCCHHHHHC
NINNINMVTCGGQATIPMVAAVSQVQAVEYGEIVATVSSRSVGPGTRQNIDEFTRTTAGA
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
VEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKDQPDEQAITASVHKMIEQVQQYVPGY
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNVKTHLNV
EECCCCEECCEEEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
TKEAALA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA