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The map label for this gene is vibA [H]

Identifier: 157961935

GI number: 157961935

Start: 2558294

End: 2559073

Strand: Reverse

Name: vibA [H]

Synonym: Spea_2114

Alternate gene names: 157961935

Gene position: 2559073-2558294 (Counterclockwise)

Preceding gene: 157961936

Following gene: 157961933

Centisome position: 49.45

GC content: 46.41

Gene sequence:

>780_bases
ATGCCTATTACTGCAGTAACGGGATCATCCTCAGGCATTGGCGCGGCTGTTTGTGCTCAACTTGAAAAAGCGGGTCACAC
GATTATTGGTATAGATAGAATAGCTGATGACAAATTTACCCGTATTGCTGCTGATTTAGCGACAGCTGAAGGTCGTCAAA
ACGCCATAAACCATGTTTATGAACAGTCTAAAGGTACACTAGATGGGTTAGTATGTTGTGCAGGCCTTGGTGTCACTGCG
CCTAATTGTGGACTCATCGTTGAGGTTAATTACTTTGGTGTCACATCTTTAGTTACTGGTCTCTATGACGCATTAGCTCA
AGGTACGCAACCTTCTGTTGTCGTTATCGGCTCTGTCGCGGCAAATCAGCAAGTTGCCACGCCGCATCCTATGGCGTTAG
CCATGCTAGATAATGACGAAGCGCTAGCGACACAATTAGCAAATGAAGATCAGCAAGCTCATATCGCATATGCAGCGTCA
AAGTATGCGGTGACCAGTTGGTGTCGTCAAACTGCTGTAAACTGGGGGCCTAAAGGGATCAGAGTCAACATCATCGCACC
TGGCGCAGTAGAAACGCCTTTGCATCAAGCATCTAAAGATGATGCTCGATATGGCGAGGCTGTAAGAAACTTTGTCGCAC
CGATTGGCCGCAATAGTGAAGCAGCAGAAATCGCCTCAGTGGTAAGCTTCTTACAATCAAAACAAGCCAGTTTTATCCAT
GGCAGTGTAATTTTTGTCGATGGTGGCATGGATGCAATGATGCGCGCAAACACCTTTTAG

Upstream 100 bases:

>100_bases
ACAGACTCTCTGGGCATACTGGTTTTATCTACATCTATTATCGCTTTTATATTTACTTTGTTAAGCGCAGAGTATTGCTT
ACGATTAAAGGAGAAACAAT

Downstream 100 bases:

>100_bases
GCCGTAAATTAAAGCATATTAAAATAATCAGCCAACTAAAAGCCCCTAGTATTTCTGCTAGGGGCTTCATCTTGAATGTG
GCGGAGAGATAGCTGACTTT

Product: 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MPITAVTGSSSGIGAAVCAQLEKAGHTIIGIDRIADDKFTRIAADLATAEGRQNAINHVYEQSKGTLDGLVCCAGLGVTA
PNCGLIVEVNYFGVTSLVTGLYDALAQGTQPSVVVIGSVAANQQVATPHPMALAMLDNDEALATQLANEDQQAHIAYAAS
KYAVTSWCRQTAVNWGPKGIRVNIIAPGAVETPLHQASKDDARYGEAVRNFVAPIGRNSEAAEIASVVSFLQSKQASFIH
GSVIFVDGGMDAMMRANTF

Sequences:

>Translated_259_residues
MPITAVTGSSSGIGAAVCAQLEKAGHTIIGIDRIADDKFTRIAADLATAEGRQNAINHVYEQSKGTLDGLVCCAGLGVTA
PNCGLIVEVNYFGVTSLVTGLYDALAQGTQPSVVVIGSVAANQQVATPHPMALAMLDNDEALATQLANEDQQAHIAYAAS
KYAVTSWCRQTAVNWGPKGIRVNIIAPGAVETPLHQASKDDARYGEAVRNFVAPIGRNSEAAEIASVVSFLQSKQASFIH
GSVIFVDGGMDAMMRANTF
>Mature_258_residues
PITAVTGSSSGIGAAVCAQLEKAGHTIIGIDRIADDKFTRIAADLATAEGRQNAINHVYEQSKGTLDGLVCCAGLGVTAP
NCGLIVEVNYFGVTSLVTGLYDALAQGTQPSVVVIGSVAANQQVATPHPMALAMLDNDEALATQLANEDQQAHIAYAASK
YAVTSWCRQTAVNWGPKGIRVNIIAPGAVETPLHQASKDDARYGEAVRNFVAPIGRNSEAAEIASVVSFLQSKQASFIHG
SVIFVDGGMDAMMRANTF

Specific function: Involved in an early step of the biosynthesis of the catechol siderophore vibriobactin. Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787335, Length=269, Percent_Identity=28.2527881040892, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=24.2537313432836, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=278, Percent_Identity=26.2589928057554, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=28.7272727272727, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=277, Percent_Identity=26.7148014440433, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=26.5454545454545, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=267, Percent_Identity=27.3408239700375, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=287, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=278, Percent_Identity=26.6187050359712, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=268, Percent_Identity=26.4925373134328, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644337, Length=102, Percent_Identity=38.2352941176471, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=27.1698113207547, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=278, Percent_Identity=26.2589928057554, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI23397609, Length=269, Percent_Identity=27.8810408921933, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=29.5019157088123, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR003560
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.28 [H]

Molecular weight: Translated: 27004; Mature: 26873

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITAVTGSSSGIGAAVCAQLEKAGHTIIGIDRIADDKFTRIAADLATAEGRQNAINHVY
CCEEEECCCCCCHHHHHHHHHHHCCCEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHH
EQSKGTLDGLVCCAGLGVTAPNCGLIVEVNYFGVTSLVTGLYDALAQGTQPSVVVIGSVA
HHCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECC
ANQQVATPHPMALAMLDNDEALATQLANEDQQAHIAYAASKYAVTSWCRQTAVNWGPKGI
CCCCCCCCCCEEEEEECCCHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCE
RVNIIAPGAVETPLHQASKDDARYGEAVRNFVAPIGRNSEAAEIASVVSFLQSKQASFIH
EEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEE
GSVIFVDGGMDAMMRANTF
CEEEEEECCHHHHHHCCCC
>Mature Secondary Structure 
PITAVTGSSSGIGAAVCAQLEKAGHTIIGIDRIADDKFTRIAADLATAEGRQNAINHVY
CEEEECCCCCCHHHHHHHHHHHCCCEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHH
EQSKGTLDGLVCCAGLGVTAPNCGLIVEVNYFGVTSLVTGLYDALAQGTQPSVVVIGSVA
HHCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECC
ANQQVATPHPMALAMLDNDEALATQLANEDQQAHIAYAASKYAVTSWCRQTAVNWGPKGI
CCCCCCCCCCEEEEEECCCHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCE
RVNIIAPGAVETPLHQASKDDARYGEAVRNFVAPIGRNSEAAEIASVVSFLQSKQASFIH
EEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEE
GSVIFVDGGMDAMMRANTF
CEEEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371453; 10952301 [H]