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The map label for this gene is yjjL [H]

Identifier: 157961936

GI number: 157961936

Start: 2559224

End: 2560579

Strand: Reverse

Name: yjjL [H]

Synonym: Spea_2115

Alternate gene names: 157961936

Gene position: 2560579-2559224 (Counterclockwise)

Preceding gene: 157961937

Following gene: 157961935

Centisome position: 49.48

GC content: 45.13

Gene sequence:

>1356_bases
ATGGTCAGCTGCGCTAACAATAACGGACAACAGTGGCGCCGACACGGTCTGCTACTGTTGTTGACCTTATTTTATGGTGA
AACTTTCATCGGTAGGCAAATTATTGCAGTGATGATTGAGCCCATAAAATTAGAGTTCGGAGCCAGCGACACCCAGATGG
GCTTAATGTCGGGGCTGGCGTTTGCTGTTGTGTTTGCGGTTTTAGGCTTACCTGCCGGGCAGTTAGCAGATAAAAAATCA
CGAACAAGAATATTGGCTTTTTGCGCCTTAGCTTGGGCATTTGCAACCGCGCTATGTGGTTTTGCTGTTGGCTTTTATAT
GTTGGTCGCCGCGCGGATGCTTGTAGCAGTAGCAGAGGTCCCTATCGGCTCCTCTTCAATGTCTCTTATTGCCGATTTAT
ATCCGTTAAATAAGCGTGCATTTGCCATTAGTTGTTACAGCTCAGCAGCGACTCTGGCCTCTATTGTAGCATTAGGTCTT
GGCGCATATCTCATTGGTCTATTGGGGTGGCGCCACACTTTTCTTTTACTCTCTATCCCCGCTCTGATCCTTTCGGCGAT
ATTTTTCATTTTTGTAAAAGAGCCAATAAGAGGTCAATTTAATAACAAAGCACAAGCTAACTTAACCGCAGTACAAACAG
AACTGAACACTAGCAACGACACGTTAGCTGATACACTACGCTCCCTATGGGCCCACAAGCGATTTAAATTACTCGTTTTT
TCAAGTTCAATGGCAACGATGTCGGCAAATGCTTTTGGTATGTGGAATATTACTTTTTTAATGCGAAGCCACCAATTAGA
TCTATACAGTGCTGGCGTACTCGCCGGAATTATTGGCGGTGGCGCAGCTGCAATCGGGATTCTTTTAGGCGGCTATTTAG
CAGATAAACGTAGTGAACAAACCTCGCCATTACAGCTACCAATAATAGGCCATATTCTTGGGATCAGCTCTCTGTACTTT
TATCTGCTGTGGCCAAGTGAGCAGACCATACTACTTTTTGGCTATAACGTGCCAGTCGCGATGTTTGCTTGCGCGCTAAC
GAGCTTTTTTTCTGTTTGGTGGGTAGGACCCTGCTTTAGCTTACTCACTCATTTAGTCCCAACTCATCAACGAGCCGTTG
CCATCGCATGTCAATCAATCTTAGTTTCGTTACTCGGAATGGGAATAGGCCCTGTTTTAGTCGGCGGTCTTAGTGACATT
CTTTCGCCTAGTATGGGCCTTGAATCTTTGAGGTATGCCCTCATCTTCAGTAGCTTTTCGACAATCATAGCCGTAATACT
GTTAATCAGGCTTAATCGCATATTTGTGACTAACGAGCCAGATAATGCCGGTGTGAACTCATCGAGCCTGTTATAA

Upstream 100 bases:

>100_bases
GAGATATACTGCTCGAACTGGGTAGGCGTGGCACTGTTGGCGGCCAAGAAGATATGATTGACGACACGGCAATGAATATG
GCCAGAGAACGCGCATAACT

Downstream 100 bases:

>100_bases
AACACTAAAACCTTGAGTGCCAGATCTAGTCTCTTTAAACGAGGAGGCAAACAGACTCTCTGGGCATACTGGTTTTATCT
ACATCTATTATCGCTTTTAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MVSCANNNGQQWRRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGASDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYSSAATLASIVALGL
GAYLIGLLGWRHTFLLLSIPALILSAIFFIFVKEPIRGQFNNKAQANLTAVQTELNTSNDTLADTLRSLWAHKRFKLLVF
SSSMATMSANAFGMWNITFLMRSHQLDLYSAGVLAGIIGGGAAAIGILLGGYLADKRSEQTSPLQLPIIGHILGISSLYF
YLLWPSEQTILLFGYNVPVAMFACALTSFFSVWWVGPCFSLLTHLVPTHQRAVAIACQSILVSLLGMGIGPVLVGGLSDI
LSPSMGLESLRYALIFSSFSTIIAVILLIRLNRIFVTNEPDNAGVNSSSLL

Sequences:

>Translated_451_residues
MVSCANNNGQQWRRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGASDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYSSAATLASIVALGL
GAYLIGLLGWRHTFLLLSIPALILSAIFFIFVKEPIRGQFNNKAQANLTAVQTELNTSNDTLADTLRSLWAHKRFKLLVF
SSSMATMSANAFGMWNITFLMRSHQLDLYSAGVLAGIIGGGAAAIGILLGGYLADKRSEQTSPLQLPIIGHILGISSLYF
YLLWPSEQTILLFGYNVPVAMFACALTSFFSVWWVGPCFSLLTHLVPTHQRAVAIACQSILVSLLGMGIGPVLVGGLSDI
LSPSMGLESLRYALIFSSFSTIIAVILLIRLNRIFVTNEPDNAGVNSSSLL
>Mature_451_residues
MVSCANNNGQQWRRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGASDTQMGLMSGLAFAVVFAVLGLPAGQLADKKS
RTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEVPIGSSSMSLIADLYPLNKRAFAISCYSSAATLASIVALGL
GAYLIGLLGWRHTFLLLSIPALILSAIFFIFVKEPIRGQFNNKAQANLTAVQTELNTSNDTLADTLRSLWAHKRFKLLVF
SSSMATMSANAFGMWNITFLMRSHQLDLYSAGVLAGIIGGGAAAIGILLGGYLADKRSEQTSPLQLPIIGHILGISSLYF
YLLWPSEQTILLFGYNVPVAMFACALTSFFSVWWVGPCFSLLTHLVPTHQRAVAIACQSILVSLLGMGIGPVLVGGLSDI
LSPSMGLESLRYALIFSSFSTIIAVILLIRLNRIFVTNEPDNAGVNSSSLL

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=438, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367379, Length=434, Percent_Identity=22.8110599078341, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789152, Length=323, Percent_Identity=22.2910216718266, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082320, Length=292, Percent_Identity=23.972602739726, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654041, Length=408, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654037, Length=408, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640209, Length=147, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48527; Mature: 48527

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSCANNNGQQWRRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGASDTQMGLMSGLA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
FAVVFAVLGLPAGQLADKKSRTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEV
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIGSSSMSLIADLYPLNKRAFAISCYSSAATLASIVALGLGAYLIGLLGWRHTFLLLSIP
CCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALILSAIFFIFVKEPIRGQFNNKAQANLTAVQTELNTSNDTLADTLRSLWAHKRFKLLVF
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
SSSMATMSANAFGMWNITFLMRSHQLDLYSAGVLAGIIGGGAAAIGILLGGYLADKRSEQ
ECCHHHHCCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
TSPLQLPIIGHILGISSLYFYLLWPSEQTILLFGYNVPVAMFACALTSFFSVWWVGPCFS
CCCEECHHHHHHHHHHHHHEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLTHLVPTHQRAVAIACQSILVSLLGMGIGPVLVGGLSDILSPSMGLESLRYALIFSSFS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIIAVILLIRLNRIFVTNEPDNAGVNSSSLL
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MVSCANNNGQQWRRHGLLLLLTLFYGETFIGRQIIAVMIEPIKLEFGASDTQMGLMSGLA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHH
FAVVFAVLGLPAGQLADKKSRTRILAFCALAWAFATALCGFAVGFYMLVAARMLVAVAEV
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIGSSSMSLIADLYPLNKRAFAISCYSSAATLASIVALGLGAYLIGLLGWRHTFLLLSIP
CCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALILSAIFFIFVKEPIRGQFNNKAQANLTAVQTELNTSNDTLADTLRSLWAHKRFKLLVF
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
SSSMATMSANAFGMWNITFLMRSHQLDLYSAGVLAGIIGGGAAAIGILLGGYLADKRSEQ
ECCHHHHCCCCCEEEEHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
TSPLQLPIIGHILGISSLYFYLLWPSEQTILLFGYNVPVAMFACALTSFFSVWWVGPCFS
CCCEECHHHHHHHHHHHHHEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLTHLVPTHQRAVAIACQSILVSLLGMGIGPVLVGGLSDILSPSMGLESLRYALIFSSFS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIIAVILLIRLNRIFVTNEPDNAGVNSSSLL
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]