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The map label for this gene is corA [H]

Identifier: 157961901

GI number: 157961901

Start: 2519235

End: 2520182

Strand: Reverse

Name: corA [H]

Synonym: Spea_2080

Alternate gene names: 157961901

Gene position: 2520182-2519235 (Counterclockwise)

Preceding gene: 157961903

Following gene: 157961891

Centisome position: 48.7

GC content: 37.76

Gene sequence:

>948_bases
ATGATCACTGCGTATTGCTATGAACATCACCAAGTCACTGCTACAACTATCAATATTAAAGAGTCTTTACCTGAAACAGC
ATTATGGCTGGATATATATCAACCCATTGAGGCTGAAAGGTTATGGTTATCCAGCTTTTCCTCCGCTGAGGTGCCCGATA
GGGAAGATAGAAATGAAATTGAGGCTTCTTCGCGCTTTTACCAAAACAAAGATGGTTTACACGTAAACTCCTTATTTAGT
CAAAAGTCTGGCCAGACGCTAAGCTCAGTTAATATTTACTTTAATCTTAGAAAGCAGTTATTGATCACCATTCGAGATGA
TAATGAACGATTATTAGACTCATTATTGACCAGTCTGCAAAAAGAACCCACTCCACAGATCACACCACTGCAATTGTTCA
TTCAGCTCTTCAAAATGAAAGTTGACCATCTAGCCGATCTTATTGAAGAGATCTATAGCACTCTGGAAAATGTTGGCCAT
GAAATATTTGAAAAAGATCATATTGATAAGGTGTTTAAACTGATCACAAACAGGGAAGACACCAATGGAAAGATCCGCCT
AAACCTACTCGATACTCAACGTGCGCTGAATTACATACTGCGTGATAACCAAATTGAACTGACTAACGATGAGGCAAAAG
ATATTAATAATATGCTATCTGACATTGCATCGTTAATACCACATACTCAGTTTATTTTTGAAAAAATCAACTTTTTAATG
GATGCCGCCATGGGTTTTACCGGTTTGCAGCAGAATAAAATTAGCAAAATTTTTTCTATCACGGCAATAGTTTTTCTCCC
GCCAACATTAATAGCAAGTACCTATGGTATGAACTTTGAGAATATACCAGAGGTACATTGGCACTATGGTTATCCATGGT
CCATAGCACTAATGTTCGCCAGTGCAGCAGCCACATTTGGTTTTTTCAAATTAAAGCGCTGGTTATAG

Upstream 100 bases:

>100_bases
AGGGAAGTATCATTCAATTTTAATACTATATCTTTGCAATCATTGACTAATATTTAATTGTCAGTTTCAACTAATATCAC
TCTTTTGCTATGGGGCCAAC

Downstream 100 bases:

>100_bases
TCATACTAGACATTTCGTTGCCAGTCGACTTTGTTGACAGGCTCGAGGGAATGACTATAGGCGATAACGAATATAGTGGT
GTTATAAGCTAGTACGATTA

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MITAYCYEHHQVTATTINIKESLPETALWLDIYQPIEAERLWLSSFSSAEVPDREDRNEIEASSRFYQNKDGLHVNSLFS
QKSGQTLSSVNIYFNLRKQLLITIRDDNERLLDSLLTSLQKEPTPQITPLQLFIQLFKMKVDHLADLIEEIYSTLENVGH
EIFEKDHIDKVFKLITNREDTNGKIRLNLLDTQRALNYILRDNQIELTNDEAKDINNMLSDIASLIPHTQFIFEKINFLM
DAAMGFTGLQQNKISKIFSITAIVFLPPTLIASTYGMNFENIPEVHWHYGYPWSIALMFASAAATFGFFKLKRWL

Sequences:

>Translated_315_residues
MITAYCYEHHQVTATTINIKESLPETALWLDIYQPIEAERLWLSSFSSAEVPDREDRNEIEASSRFYQNKDGLHVNSLFS
QKSGQTLSSVNIYFNLRKQLLITIRDDNERLLDSLLTSLQKEPTPQITPLQLFIQLFKMKVDHLADLIEEIYSTLENVGH
EIFEKDHIDKVFKLITNREDTNGKIRLNLLDTQRALNYILRDNQIELTNDEAKDINNMLSDIASLIPHTQFIFEKINFLM
DAAMGFTGLQQNKISKIFSITAIVFLPPTLIASTYGMNFENIPEVHWHYGYPWSIALMFASAAATFGFFKLKRWL
>Mature_315_residues
MITAYCYEHHQVTATTINIKESLPETALWLDIYQPIEAERLWLSSFSSAEVPDREDRNEIEASSRFYQNKDGLHVNSLFS
QKSGQTLSSVNIYFNLRKQLLITIRDDNERLLDSLLTSLQKEPTPQITPLQLFIQLFKMKVDHLADLIEEIYSTLENVGH
EIFEKDHIDKVFKLITNREDTNGKIRLNLLDTQRALNYILRDNQIELTNDEAKDINNMLSDIASLIPHTQFIFEKINFLM
DAAMGFTGLQQNKISKIFSITAIVFLPPTLIASTYGMNFENIPEVHWHYGYPWSIALMFASAAATFGFFKLKRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=320, Percent_Identity=37.5, Blast_Score=225, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36474; Mature: 36474

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAYCYEHHQVTATTINIKESLPETALWLDIYQPIEAERLWLSSFSSAEVPDREDRNEI
CEEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHH
EASSRFYQNKDGLHVNSLFSQKSGQTLSSVNIYFNLRKQLLITIRDDNERLLDSLLTSLQ
HHHHHHHCCCCCCCHHHHHHCCCCCCHHEEHEEEEEEEEEEEEEECCCHHHHHHHHHHHH
KEPTPQITPLQLFIQLFKMKVDHLADLIEEIYSTLENVGHEIFEKDHIDKVFKLITNRED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TNGKIRLNLLDTQRALNYILRDNQIELTNDEAKDINNMLSDIASLIPHTQFIFEKINFLM
CCCEEEEEEEHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFTGLQQNKISKIFSITAIVFLPPTLIASTYGMNFENIPEVHWHYGYPWSIALMFA
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHH
SAAATFGFFKLKRWL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MITAYCYEHHQVTATTINIKESLPETALWLDIYQPIEAERLWLSSFSSAEVPDREDRNEI
CEEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHH
EASSRFYQNKDGLHVNSLFSQKSGQTLSSVNIYFNLRKQLLITIRDDNERLLDSLLTSLQ
HHHHHHHCCCCCCCHHHHHHCCCCCCHHEEHEEEEEEEEEEEEEECCCHHHHHHHHHHHH
KEPTPQITPLQLFIQLFKMKVDHLADLIEEIYSTLENVGHEIFEKDHIDKVFKLITNRED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TNGKIRLNLLDTQRALNYILRDNQIELTNDEAKDINNMLSDIASLIPHTQFIFEKINFLM
CCCEEEEEEEHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFTGLQQNKISKIFSITAIVFLPPTLIASTYGMNFENIPEVHWHYGYPWSIALMFA
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHH
SAAATFGFFKLKRWL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]