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The map label for this gene is aspC [H]

Identifier: 157961891

GI number: 157961891

Start: 2509307

End: 2510500

Strand: Reverse

Name: aspC [H]

Synonym: Spea_2070

Alternate gene names: 157961891

Gene position: 2510500-2509307 (Counterclockwise)

Preceding gene: 157961901

Following gene: 157961889

Centisome position: 48.52

GC content: 46.31

Gene sequence:

>1194_bases
ATGTTCAACAAATTAACCGCTATGCCTGCCGATCCCATCTTAGGTTTACTCACTAAATACCGTGAAGATAGCCAGCCTCA
AAAAGTCGATCTAGGCGTAGGTGTTTATAAAGATGAGTCTGGTCACACCCCGATCCTCTCCTGTGTGAAAAAGGCTGAGA
AATTCCGATTAGAGACTGAGGCAACAAAAGTTTACATCGGACCAACAGGTTCAGCCGATTTTAATCGTCTTATGTCTGAG
CTGGCTTTTGGTATAGATAACCCTGCAATTCTCGCCAACCGAGTCCGCACCGTATCAACGCCAGGCGGTACGGGAGCATT
AAGAGTGGCAGCCGACTTTATTAAACGCTGCAACCCAAATACTGTTTTGTGGGTCAGCGATCCGACTTGGGCCAACCACA
CTGGATTATTTGAAGCAGCGGGTATTACCGTCAAGACCTACCCATACTATGATTACGATTCAAAATCACTAAAGTTCGAT
GAAATGAAGGCTGCGCTGTCACAAGTGAGTTCCGATGATGTCGTGCTGCTGCACGCGTGTTGCCACAACCCAAGCGGTAT
GGACTTAACACCAGCCCAGTGGGACGAAATCATTGCTCTTACAGCCGAAAACGGTTTTACACCACTTATCGATATGGCCT
ATCAGGGCTTTGGTGATGGCGTTGATGAAGATGCTTATGGCGTACGTAAGATGGCTGCGACGGTTCAGAATATGATCCTA
TGCAGTTCATGCTCAAAAAACTTTGGATTATATCGAGAGCGTATTGGAGCCTGCAGTATCGTAGGCAGTGACTCTACCCG
TGCCGACATTGCTTTCTCAGTACTTTTGTATGTTGTGCGCTGTATTTACTCAATGCCACCAGCACATGGCGCAGCTATTG
TTGAAACCATTCTTGGCTCAGATGAGCTTAAACAGCAATGGCTCGATGAGCTAAAGGAGATGCGTGAACGCATTAATGGT
AATCGTGCCATGCTGGTTAATAAGTTAAAAGAAAAAGGCGTACAACGTGATTTTGACTTTATTGCAGAGCAAAAAGGCAT
GTTTTCCTTCCTAGGGATCACCCCAGCCCAAGTTGCAGAGCTGCAAGAACATTACAGCGTATACATGGTAGATTCTAGCC
GCATCAGCATAGCGGGCATTGGCACAGGCAATGTTGATTACCTAGCCGAGTCCATTGCCAAAGTCATCTGTTAA

Upstream 100 bases:

>100_bases
TTATTATAAAACCTATCCATTTTTACATTTATTAAGTTACTCTAAGTTAATAATGAAAACGGCTGAACACTTGCCGATAA
CAGAAGAGGTAACCTCAGAC

Downstream 100 bases:

>100_bases
GAATTTATATATAAAGCAATTAAAAAAGCCGACACTTCTATGTGTCGGCTTTCTTTTTAAGCTGGAGCTAGCATATGTTT
AAGCATTTTTAGCTGCAAAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MFNKLTAMPADPILGLLTKYREDSQPQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETEATKVYIGPTGSADFNRLMSE
LAFGIDNPAILANRVRTVSTPGGTGALRVAADFIKRCNPNTVLWVSDPTWANHTGLFEAAGITVKTYPYYDYDSKSLKFD
EMKAALSQVSSDDVVLLHACCHNPSGMDLTPAQWDEIIALTAENGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVQNMIL
CSSCSKNFGLYRERIGACSIVGSDSTRADIAFSVLLYVVRCIYSMPPAHGAAIVETILGSDELKQQWLDELKEMRERING
NRAMLVNKLKEKGVQRDFDFIAEQKGMFSFLGITPAQVAELQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIC

Sequences:

>Translated_397_residues
MFNKLTAMPADPILGLLTKYREDSQPQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETEATKVYIGPTGSADFNRLMSE
LAFGIDNPAILANRVRTVSTPGGTGALRVAADFIKRCNPNTVLWVSDPTWANHTGLFEAAGITVKTYPYYDYDSKSLKFD
EMKAALSQVSSDDVVLLHACCHNPSGMDLTPAQWDEIIALTAENGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVQNMIL
CSSCSKNFGLYRERIGACSIVGSDSTRADIAFSVLLYVVRCIYSMPPAHGAAIVETILGSDELKQQWLDELKEMRERING
NRAMLVNKLKEKGVQRDFDFIAEQKGMFSFLGITPAQVAELQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIC
>Mature_397_residues
MFNKLTAMPADPILGLLTKYREDSQPQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETEATKVYIGPTGSADFNRLMSE
LAFGIDNPAILANRVRTVSTPGGTGALRVAADFIKRCNPNTVLWVSDPTWANHTGLFEAAGITVKTYPYYDYDSKSLKFD
EMKAALSQVSSDDVVLLHACCHNPSGMDLTPAQWDEIIALTAENGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVQNMIL
CSSCSKNFGLYRERIGACSIVGSDSTRADIAFSVLLYVVRCIYSMPPAHGAAIVETILGSDELKQQWLDELKEMRERING
NRAMLVNKLKEKGVQRDFDFIAEQKGMFSFLGITPAQVAELQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIC

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=390, Percent_Identity=40.5128205128205, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI4504067, Length=398, Percent_Identity=37.9396984924623, Blast_Score=278, Evalue=5e-75,
Organism=Homo sapiens, GI117414139, Length=385, Percent_Identity=24.6753246753247, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=50, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=40.8060453400504, Blast_Score=338, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=39.4936708860759, Blast_Score=311, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=40, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17569539, Length=396, Percent_Identity=35.1010101010101, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=29.1989664082687, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI25147136, Length=206, Percent_Identity=36.4077669902913, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17550384, Length=267, Percent_Identity=26.9662921348315, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=37.2839506172839, Blast_Score=289, Evalue=4e-79,
Organism=Saccharomyces cerevisiae, GI6322743, Length=424, Percent_Identity=33.4905660377358, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.6464646464646, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=39.6464646464646, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=40.1028277634961, Blast_Score=297, Evalue=9e-81,
Organism=Drosophila melanogaster, GI24654046, Length=391, Percent_Identity=38.3631713554987, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI19922362, Length=391, Percent_Identity=38.3631713554987, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43543; Mature: 43543

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKLTAMPADPILGLLTKYREDSQPQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETE
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCCHHHHHHHHHHHHEEECC
ATKVYIGPTGSADFNRLMSELAFGIDNPAILANRVRTVSTPGGTGALRVAADFIKRCNPN
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCC
TVLWVSDPTWANHTGLFEAAGITVKTYPYYDYDSKSLKFDEMKAALSQVSSDDVVLLHAC
EEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPSGMDLTPAQWDEIIALTAENGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVQNMIL
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CSSCSKNFGLYRERIGACSIVGSDSTRADIAFSVLLYVVRCIYSMPPAHGAAIVETILGS
HHHCCCCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
DELKQQWLDELKEMRERINGNRAMLVNKLKEKGVQRDFDFIAEQKGMFSFLGITPAQVAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHHH
LQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIC
HHHCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MFNKLTAMPADPILGLLTKYREDSQPQKVDLGVGVYKDESGHTPILSCVKKAEKFRLETE
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEECCCCCCHHHHHHHHHHHHEEECC
ATKVYIGPTGSADFNRLMSELAFGIDNPAILANRVRTVSTPGGTGALRVAADFIKRCNPN
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHCCCC
TVLWVSDPTWANHTGLFEAAGITVKTYPYYDYDSKSLKFDEMKAALSQVSSDDVVLLHAC
EEEEECCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPSGMDLTPAQWDEIIALTAENGFTPLIDMAYQGFGDGVDEDAYGVRKMAATVQNMIL
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CSSCSKNFGLYRERIGACSIVGSDSTRADIAFSVLLYVVRCIYSMPPAHGAAIVETILGS
HHHCCCCCCHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
DELKQQWLDELKEMRERINGNRAMLVNKLKEKGVQRDFDFIAEQKGMFSFLGITPAQVAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHHH
LQEHYSVYMVDSSRISIAGIGTGNVDYLAESIAKVIC
HHHCCEEEEEECCEEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]