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The map label for this gene is glcB [H]

Identifier: 157961864

GI number: 157961864

Start: 2473349

End: 2475523

Strand: Direct

Name: glcB [H]

Synonym: Spea_2043

Alternate gene names: 157961864

Gene position: 2473349-2475523 (Clockwise)

Preceding gene: 157961863

Following gene: 157961866

Centisome position: 47.8

GC content: 45.7

Gene sequence:

>2175_bases
ATGACTGCAAGGATCCGAGTCGGTGGTTTACAAATTGCTAAATCACTTTGGGAATTAGTTGATAGCGAGATCTGTCCTGG
AACTGGGATCAGCTCACAGATTTTCTGGACGAAATTTGAAGATATAGTCAACGAGCTTGGCCCAGTCAATAGACAACTAC
TAGATAAACGTGATCAATTACAAGCTCAAATCGATGAATGGCACAAAGGAAATGCACAACAATCTTTTGACTCGATTCAA
TATAAGCAGTTTCTCATGGATATTGGTTATCTAGTCGAAGAGGGGCAGCCTTTTACTATCTCTACCGAAAATGTAGATTT
AGAGATCACCACTCAAGCCGGACCTCAGTTGGTTGTGCCAGTCAAGAATGCACGCTTTGCCTTAAATGCCGCCAACGCCC
GTTGGGGGAGCCTCTACGATGCACTATATGGTACTGATGCCATTTCATTTGCAGATGGCGCAGAGATCACCAAAGAATAT
AATCCCGTGCGTGGTGCAAAGGTGATCGCTTTTGCTAAAAACCTTTTAGATACTGCAGCGCCATTAGCATCAGGGCTACA
TAGTCAAGTAACTCGATACTTCGTAGAAGATAATGCCTTAAAGGCTCTGCTAGAAAACGGTGAGCAGACTGTTTTAGTCG
AGCCAAGTAAGTTTGTTGGTTTTAAAGGTGAGGCCGAAACACCATCGGCGCTATTGCTAGTGAATAACGCTTTACATATC
GAGATCCAAATCAATCCAGATAGTTTGATTGGTCAAACTGATCTTGCTGGGGTTAAAGATTTATTAATCGAAGCCGCAGT
TACGACCATTATGGATTGTGAGGATTCAGTTGCAGCGGTTGACGCCGAAGATAAAGTGGAAGTTTATCGTAATTGGCTAG
GGCTGATGCAAGGCAAGCTGACAGCTTCACTGAAAAAGAATGGCAAAGAGATTGTACGTGAGCTAAACGATGACAGAGTA
TACACAGGCACTCATGGGCAGAGTGTAACGCTTTCTGGACGTAGTCTGCTGTTTGTCCGCAATGTCGGTCACCTAATGAC
AAATGATGCCGTGCTTGATAAAAATGGCGACGAAGTGCCTGAGGGGATCCTCGATGGCATGGTCACTGTACTGGCAGCAA
TGCACGATCTTAAAGGCAATAATAACCAGCGCAGTAATAGCCGTAAAGGCTCGGTCAATATCGTTAAGCCGAAAATGCAC
GGTCCAGAAGAAGTTCAATTCACCTGTGATCTGTTTACACGCATAGAAGATGCGTTAAAGCTTTCACGAAATACCATCAA
AGTGGGGATCATGGATGAAGAGCGTCGCACAACAGTCAATCTTAAGGAGTGTATCCGAGCGGCGCAGGAACGTGTGGTCT
TCATCAATACAGGTTTCTTAGATAGAACCGGTGATGAAATTCATACTTCTATGCTGGCTGGGCCATTTGTTGCCAAATCT
GTGATGAAACTGCAGGCGTGGATCAAGGCATACGAAGATTGGAACGTGGACATCGGCCTAGAGTGTGGCTTACAAGGTCG
CTCGCAAATAGGCAAAGGTATGTGGCCAATGCCGGATGAGATGGCTGCGATGTTAGAACAAAAAATGGGTCATCCAAAAG
CGGGAGCCAATACAGCCTGGGTTCCATCGCCTAATGGTGCAGCTTTACACGCGACCCACTATCATCAGATTAATGTTACA
CAGGTTCAAGATGAGCTTAAGCAGCGCAAGCGCGCAAGCTTGGATGATCTACTGACTATTCCACTTATGCAACAGGGAGA
GCGACTCACTGCCGAGCAAAAGCAGTTTGAGCTAGATAATAATGCACAAGGTATATTAGGTTATGTAGTCCGCTGGATTG
ACCAAGGCGTGGGCTGCTCTAAAGTGCCGGATATCAATAATGTGGGTTTGATGGAAGACAGGGCAACCTTGCGTATTTCG
TCTCAATACCTCGCTAATTGGTTGCACCATGGCGTGTGCACCAAAGATGAGGTGATGGCATCACTTAAGAAGATGGCGCA
AGTGGTCGATAAGCAAAACCAAGCCGACAGCGAATATACCAATATGGCACCGAACTTCGATGGTGTTGCGTTTAAAGCAG
CTTGCGACTTGATCTTCAAAGGGGAGCTGCAGCCATCAGGCTATACTGAGCCTTTGCTGCATGCTTATCGAAAGCAAGCA
AAACTGCAGTCGTAA

Upstream 100 bases:

>100_bases
GACAAGCTTAGTATAGGCTTGTTGGGTATGACTAAATTGAATTAAGAGCAAATGGAGAGCCATTGCTCTGCATCGCTAAA
TGGATAGATAAGGGCATATT

Downstream 100 bases:

>100_bases
TTCAACCTTAGGGGGAACCACAATAAAAAGCCCTAACCATTCGGTTAGGGCTTTCTAATGATTAAAGCAAGTTATTGATC
GCTATAGTCATTACCGTAGT

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MTARIRVGGLQIAKSLWELVDSEICPGTGISSQIFWTKFEDIVNELGPVNRQLLDKRDQLQAQIDEWHKGNAQQSFDSIQ
YKQFLMDIGYLVEEGQPFTISTENVDLEITTQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAISFADGAEITKEY
NPVRGAKVIAFAKNLLDTAAPLASGLHSQVTRYFVEDNALKALLENGEQTVLVEPSKFVGFKGEAETPSALLLVNNALHI
EIQINPDSLIGQTDLAGVKDLLIEAAVTTIMDCEDSVAAVDAEDKVEVYRNWLGLMQGKLTASLKKNGKEIVRELNDDRV
YTGTHGQSVTLSGRSLLFVRNVGHLMTNDAVLDKNGDEVPEGILDGMVTVLAAMHDLKGNNNQRSNSRKGSVNIVKPKMH
GPEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAAQERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
VMKLQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKMGHPKAGANTAWVPSPNGAALHATHYHQINVT
QVQDELKQRKRASLDDLLTIPLMQQGERLTAEQKQFELDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRIS
SQYLANWLHHGVCTKDEVMASLKKMAQVVDKQNQADSEYTNMAPNFDGVAFKAACDLIFKGELQPSGYTEPLLHAYRKQA
KLQS

Sequences:

>Translated_724_residues
MTARIRVGGLQIAKSLWELVDSEICPGTGISSQIFWTKFEDIVNELGPVNRQLLDKRDQLQAQIDEWHKGNAQQSFDSIQ
YKQFLMDIGYLVEEGQPFTISTENVDLEITTQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAISFADGAEITKEY
NPVRGAKVIAFAKNLLDTAAPLASGLHSQVTRYFVEDNALKALLENGEQTVLVEPSKFVGFKGEAETPSALLLVNNALHI
EIQINPDSLIGQTDLAGVKDLLIEAAVTTIMDCEDSVAAVDAEDKVEVYRNWLGLMQGKLTASLKKNGKEIVRELNDDRV
YTGTHGQSVTLSGRSLLFVRNVGHLMTNDAVLDKNGDEVPEGILDGMVTVLAAMHDLKGNNNQRSNSRKGSVNIVKPKMH
GPEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAAQERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
VMKLQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKMGHPKAGANTAWVPSPNGAALHATHYHQINVT
QVQDELKQRKRASLDDLLTIPLMQQGERLTAEQKQFELDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRIS
SQYLANWLHHGVCTKDEVMASLKKMAQVVDKQNQADSEYTNMAPNFDGVAFKAACDLIFKGELQPSGYTEPLLHAYRKQA
KLQS
>Mature_723_residues
TARIRVGGLQIAKSLWELVDSEICPGTGISSQIFWTKFEDIVNELGPVNRQLLDKRDQLQAQIDEWHKGNAQQSFDSIQY
KQFLMDIGYLVEEGQPFTISTENVDLEITTQAGPQLVVPVKNARFALNAANARWGSLYDALYGTDAISFADGAEITKEYN
PVRGAKVIAFAKNLLDTAAPLASGLHSQVTRYFVEDNALKALLENGEQTVLVEPSKFVGFKGEAETPSALLLVNNALHIE
IQINPDSLIGQTDLAGVKDLLIEAAVTTIMDCEDSVAAVDAEDKVEVYRNWLGLMQGKLTASLKKNGKEIVRELNDDRVY
TGTHGQSVTLSGRSLLFVRNVGHLMTNDAVLDKNGDEVPEGILDGMVTVLAAMHDLKGNNNQRSNSRKGSVNIVKPKMHG
PEEVQFTCDLFTRIEDALKLSRNTIKVGIMDEERRTTVNLKECIRAAQERVVFINTGFLDRTGDEIHTSMLAGPFVAKSV
MKLQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKMGHPKAGANTAWVPSPNGAALHATHYHQINVTQ
VQDELKQRKRASLDDLLTIPLMQQGERLTAEQKQFELDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISS
QYLANWLHHGVCTKDEVMASLKKMAQVVDKQNQADSEYTNMAPNFDGVAFKAACDLIFKGELQPSGYTEPLLHAYRKQAK
LQS

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=727, Percent_Identity=56.808803301238, Blast_Score=835, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=271, Percent_Identity=28.0442804428044, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 80084; Mature: 79953

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARIRVGGLQIAKSLWELVDSEICPGTGISSQIFWTKFEDIVNELGPVNRQLLDKRDQL
CCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCHHHHH
QAQIDEWHKGNAQQSFDSIQYKQFLMDIGYLVEEGQPFTISTENVDLEITTQAGPQLVVP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCEEEEE
VKNARFALNAANARWGSLYDALYGTDAISFADGAEITKEYNPVRGAKVIAFAKNLLDTAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
PLASGLHSQVTRYFVEDNALKALLENGEQTVLVEPSKFVGFKGEAETPSALLLVNNALHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCCCCCEEEEEECEEEE
EIQINPDSLIGQTDLAGVKDLLIEAAVTTIMDCEDSVAAVDAEDKVEVYRNWLGLMQGKL
EEEECCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHH
TASLKKNGKEIVRELNDDRVYTGTHGQSVTLSGRSLLFVRNVGHLMTNDAVLDKNGDEVP
HHHHHHCHHHHHHHCCCCEEEECCCCCEEEECCCEEEEEECCCHHHCCCEEECCCCCCCH
EGILDGMVTVLAAMHDLKGNNNQRSNSRKGSVNIVKPKMHGPEEVQFTCDLFTRIEDALK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHH
LSRNTIKVGIMDEERRTTVNLKECIRAAQERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
HCCCEEEEEEECCCCCCEECHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VMKLQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKMGHPKAGANTAW
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
VPSPNGAALHATHYHQINVTQVQDELKQRKRASLDDLLTIPLMQQGERLTAEQKQFELDN
CCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCCHHHHHCCCC
NAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISSQYLANWLHHGVCTKDEVMA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHHCCCCCHHHHHH
SLKKMAQVVDKQNQADSEYTNMAPNFDGVAFKAACDLIFKGELQPSGYTEPLLHAYRKQA
HHHHHHHHHHCCCCCCCHHHCCCCCCCCEEHHHHHCEEEECCCCCCCCCHHHHHHHHHHH
KLQS
CCCC
>Mature Secondary Structure 
TARIRVGGLQIAKSLWELVDSEICPGTGISSQIFWTKFEDIVNELGPVNRQLLDKRDQL
CCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCHHHHH
QAQIDEWHKGNAQQSFDSIQYKQFLMDIGYLVEEGQPFTISTENVDLEITTQAGPQLVVP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCEEEEE
VKNARFALNAANARWGSLYDALYGTDAISFADGAEITKEYNPVRGAKVIAFAKNLLDTAA
ECCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
PLASGLHSQVTRYFVEDNALKALLENGEQTVLVEPSKFVGFKGEAETPSALLLVNNALHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCCCCCEEEEEECEEEE
EIQINPDSLIGQTDLAGVKDLLIEAAVTTIMDCEDSVAAVDAEDKVEVYRNWLGLMQGKL
EEEECCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHH
TASLKKNGKEIVRELNDDRVYTGTHGQSVTLSGRSLLFVRNVGHLMTNDAVLDKNGDEVP
HHHHHHCHHHHHHHCCCCEEEECCCCCEEEECCCEEEEEECCCHHHCCCEEECCCCCCCH
EGILDGMVTVLAAMHDLKGNNNQRSNSRKGSVNIVKPKMHGPEEVQFTCDLFTRIEDALK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHHH
LSRNTIKVGIMDEERRTTVNLKECIRAAQERVVFINTGFLDRTGDEIHTSMLAGPFVAKS
HCCCEEEEEEECCCCCCEECHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VMKLQAWIKAYEDWNVDIGLECGLQGRSQIGKGMWPMPDEMAAMLEQKMGHPKAGANTAW
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
VPSPNGAALHATHYHQINVTQVQDELKQRKRASLDDLLTIPLMQQGERLTAEQKQFELDN
CCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCCHHHHHCCCC
NAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISSQYLANWLHHGVCTKDEVMA
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEECHHHHHHHHHCCCCCHHHHHH
SLKKMAQVVDKQNQADSEYTNMAPNFDGVAFKAACDLIFKGELQPSGYTEPLLHAYRKQA
HHHHHHHHHHCCCCCCCHHHCCCCCCCCEEHHHHHCEEEECCCCCCCCCHHHHHHHHHHH
KLQS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA