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The map label for this gene is nahR [H]

Identifier: 157961863

GI number: 157961863

Start: 2472185

End: 2473129

Strand: Direct

Name: nahR [H]

Synonym: Spea_2042

Alternate gene names: 157961863

Gene position: 2472185-2473129 (Clockwise)

Preceding gene: 157961860

Following gene: 157961864

Centisome position: 47.78

GC content: 45.82

Gene sequence:

>945_bases
ATGAATATATCTCGTATCGATTTGAATTTATTGGTTTATCTAGACGTGCTGTTACGTGAGAAAAATGTTACTAAGGCGGC
GGATCAGCTAGGGATCAGTCAACCTGCCATGAGTAATGGCTTAAAGCGGTTGAGAATATTATTCGACGATCCACTATTAA
TACGAACCAGTCAGGGGATGACACCGACTGAGCGTGCACAGGAGCTACAGCCTACTATCAGCGAGCTTATTATTGGTTTA
GAAAAAGCTGTACAACCCCGAGCCGAATTTAATGCGGCCGAGAGTGAGCAAGTGTTTCGAGTGATGGCCAGTGATTACGC
CGAAGCAACACTTATCCCCCCACTGATTGCTAGGCTTCGCACCGAGGCGCCTAATGTCATTCTCGATATCATGACACCCA
GTGACGTGAGTTTTCCCGATGTAGAGCAGGGACGCGTCGATATGGTTATCAATCGCTTCGACAGCATTCCACAATCATTT
CATCAGAAAGTGTTATGGAGTGATGATTTTAGCTGCCTGATTAGTAAGAATAATCCCGTGCTGGATAACTTCTGCCTTGA
TAGTTATTTAAAAGCCAACCATGTCTGGGTCAGTAAAACGGGGATGGGAGTTGGAGTGGGTATGGATCCTGGTGATGTAC
AAAGGTTAGGTTGGGTAGATGAAGCGCTTACCCGAATAGGAGTACAAAGACGGATCACTGTATTTACCCGGCACTATCAG
GCTGCTTGTTTATTGGCAGAGCAACAAGATTTGATCGCTACCATACCGAGTAAGATGGCAAAGCAGCATGTAAATAACGA
GCGAGTCTGTATCGTGCCACCGCCGTTTATTATTCAGCCTATCGCACTGACAATGGCCTGGAGTCCTCTACTACAGCACA
ATCCTGCCCATAAGTGGATGCGCCAACTTATAACCAAAACTGCTGATAGTTTTGGGCGTGATTAA

Upstream 100 bases:

>100_bases
CTTTAACAATATGATTAGCGGCGATTGATTACGTTGAAAATATTAGTAAGATTTGTTTAAATAAGTCTAATTTATAGTTT
TTATATCCGGTATTTATTTT

Downstream 100 bases:

>100_bases
TCCTGCACTGGTAGTGGTAAGTGATTCTATTTCAAGGGTGATGATTTATTACACCAAAATGCCGTTCTTAAATTAGTTTG
GTGAATACTGGTAATACAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNISRIDLNLLVYLDVLLREKNVTKAADQLGISQPAMSNGLKRLRILFDDPLLIRTSQGMTPTERAQELQPTISELIIGL
EKAVQPRAEFNAAESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFPDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKNNPVLDNFCLDSYLKANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMAKQHVNNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITKTADSFGRD

Sequences:

>Translated_314_residues
MNISRIDLNLLVYLDVLLREKNVTKAADQLGISQPAMSNGLKRLRILFDDPLLIRTSQGMTPTERAQELQPTISELIIGL
EKAVQPRAEFNAAESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFPDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKNNPVLDNFCLDSYLKANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMAKQHVNNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITKTADSFGRD
>Mature_314_residues
MNISRIDLNLLVYLDVLLREKNVTKAADQLGISQPAMSNGLKRLRILFDDPLLIRTSQGMTPTERAQELQPTISELIIGL
EKAVQPRAEFNAAESEQVFRVMASDYAEATLIPPLIARLRTEAPNVILDIMTPSDVSFPDVEQGRVDMVINRFDSIPQSF
HQKVLWSDDFSCLISKNNPVLDNFCLDSYLKANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
AACLLAEQQDLIATIPSKMAKQHVNNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWMRQLITKTADSFGRD

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=24.7557003257329, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081766, Length=262, Percent_Identity=25.1908396946565, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790147, Length=323, Percent_Identity=22.9102167182663, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786820, Length=160, Percent_Identity=28.125, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35309; Mature: 35309

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISRIDLNLLVYLDVLLREKNVTKAADQLGISQPAMSNGLKRLRILFDDPLLIRTSQGM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
TPTERAQELQPTISELIIGLEKAVQPRAEFNAAESEQVFRVMASDYAEATLIPPLIARLR
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEAPNVILDIMTPSDVSFPDVEQGRVDMVINRFDSIPQSFHQKVLWSDDFSCLISKNNPV
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
LDNFCLDSYLKANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
HHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AACLLAEQQDLIATIPSKMAKQHVNNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHH
RQLITKTADSFGRD
HHHHHHHHHHCCCC
>Mature Secondary Structure
MNISRIDLNLLVYLDVLLREKNVTKAADQLGISQPAMSNGLKRLRILFDDPLLIRTSQGM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
TPTERAQELQPTISELIIGLEKAVQPRAEFNAAESEQVFRVMASDYAEATLIPPLIARLR
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEAPNVILDIMTPSDVSFPDVEQGRVDMVINRFDSIPQSFHQKVLWSDDFSCLISKNNPV
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
LDNFCLDSYLKANHVWVSKTGMGVGVGMDPGDVQRLGWVDEALTRIGVQRRITVFTRHYQ
HHHHHHHHHHHCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AACLLAEQQDLIATIPSKMAKQHVNNERVCIVPPPFIIQPIALTMAWSPLLQHNPAHKWM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHH
RQLITKTADSFGRD
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]