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The map label for this gene is pabB [H]

Identifier: 157961858

GI number: 157961858

Start: 2463805

End: 2465277

Strand: Reverse

Name: pabB [H]

Synonym: Spea_2037

Alternate gene names: 157961858

Gene position: 2465277-2463805 (Counterclockwise)

Preceding gene: 157961861

Following gene: 157961857

Centisome position: 47.64

GC content: 45.21

Gene sequence:

>1473_bases
ATGAACAAATTGGCGCAAAATGCAGTATTTTCGAAGCGTCTTGATTGGAATTTAAGCACAACTGAAGTTTTTGACTATTT
TTCAGATTTACCTTGGTCAATCCTTCTCGATTCGGCAGACGCCGATCACGTAGATGCAAAATTTGATGTGATCTGTGCCG
AGCCTATTGCCACCCTTGTAACTCAGGCTCAATCGACTATTGTAACCCGCTCTAAAGATAGAGCGCCGCTCTACATGCTT
GGTAATGTAAATCTGCATTTTGAAGCTAGCGTTACCGAAGTAAGTGGTAAACCGTTCGATGTCGTCAAGCAGCTAATTAA
CGAATACTATCCGCAGAAAAAACAGAGCCCGTTTCTGTTTTCTGGCGGAGTCATGGGCAGTTTTAGCTATGATCTCGCCC
GCGGAATTGAAAAACTGCCTGTCATTGCAAACAATGATATATCGCTTCCAGAAATGAACCTGGGCTGTTACGACTGGGCA
CTTGTATTTGATTATGAGATCAAGTGTTGGCATCTAGTTCATTATCTATCTGAGCAGGCGTTAGAAGAACTCGAACAGAG
ACTGAATGCTCTTGTGATTGCTGCTAAACCTTCAAAGCTTAAGTTAACTGAAAACTTTGCACTCGACGGGCAATGGCACA
ACCAACTGTCAGAACAAGAATACTGTCATCGATTTGCCAAAGTTCAGCAGTATCTCCATAGCGGAGATTGCTATCAAATT
AACTTAACTCAACGCTTTAGTGCCGATTACAAAGGCGATGAGTGGCAAGCGTATAAGACGCTACGTCAAACTAATGCTGC
CCCCTTCTCGGCGTTTATCCGCTTAGAGCAGCATGCCTTGTTATCGATATCTCCAGAGCGCTTTATACAACATCAACTGG
GTAAAGTGCAGACTAAACCTATTAAAGGCACTATGCCTAGAGATAAAGACCCTCACCGAGACTATCAACTTGCTGAGCAG
TTAAAGGCCTCAGAAAAAGATCGTGCTGAAAACTTAATGATTGTTGACCTTCTGCGTAATGATATTGGTAAGGTCGCTGC
GCCGGGGAGCGTCAATGTACCTCGACTTTTCGATGTCGAAAGCTTTCCTGCCGTGCATCATCTTGTGAGCACGATAACCG
CTACACTGCAGCCAAACCTTTGTCCGACTGACCTATTGCAGGCCTGTTTCCCTGGTGGCTCGATTACTGGGGCCCCGAAG
ATCCGTGCAATGGAAATCATCGAAGAGCTTGAACCGTCTAGAAGAAGTATCTATTGTGGATCTATCGGTTACATCAGCCA
AGATGGCAATATGGATACCAGCATCACTATTCGTACCCTGCTCGGGCAGAGAAAGATAGATAATCCAGATGCTGGTGGAA
CCCTGTACTGTTGGGCTGGTGGAGGTATCGTGGCCGACTCCAAAGTCGACGCCGAATATCAGGAAAGTTTCGATAAAGTC
AGCCGGATCTTGCCTGTGTTGTCACAAATGTAA

Upstream 100 bases:

>100_bases
CCTTTAAAGCTCACATGTTTTGTTTTTATTACTTGTGTAAGCAATATGATACTCTTTCGCGAGTTTGAGTTAAACATCAC
ATTTTAGATAGGGTTAACAG

Downstream 100 bases:

>100_bases
TTTAACCTAGCCTAGAGCTATCCCCTTTAAAACTAAAAGGATGTTTAATGAAGCTGGCAGAGTTTAGACTCAGGTATAAC
CTTAATACTTTGCCAGAGCT

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNKLAQNAVFSKRLDWNLSTTEVFDYFSDLPWSILLDSADADHVDAKFDVICAEPIATLVTQAQSTIVTRSKDRAPLYML
GNVNLHFEASVTEVSGKPFDVVKQLINEYYPQKKQSPFLFSGGVMGSFSYDLARGIEKLPVIANNDISLPEMNLGCYDWA
LVFDYEIKCWHLVHYLSEQALEELEQRLNALVIAAKPSKLKLTENFALDGQWHNQLSEQEYCHRFAKVQQYLHSGDCYQI
NLTQRFSADYKGDEWQAYKTLRQTNAAPFSAFIRLEQHALLSISPERFIQHQLGKVQTKPIKGTMPRDKDPHRDYQLAEQ
LKASEKDRAENLMIVDLLRNDIGKVAAPGSVNVPRLFDVESFPAVHHLVSTITATLQPNLCPTDLLQACFPGGSITGAPK
IRAMEIIEELEPSRRSIYCGSIGYISQDGNMDTSITIRTLLGQRKIDNPDAGGTLYCWAGGGIVADSKVDAEYQESFDKV
SRILPVLSQM

Sequences:

>Translated_490_residues
MNKLAQNAVFSKRLDWNLSTTEVFDYFSDLPWSILLDSADADHVDAKFDVICAEPIATLVTQAQSTIVTRSKDRAPLYML
GNVNLHFEASVTEVSGKPFDVVKQLINEYYPQKKQSPFLFSGGVMGSFSYDLARGIEKLPVIANNDISLPEMNLGCYDWA
LVFDYEIKCWHLVHYLSEQALEELEQRLNALVIAAKPSKLKLTENFALDGQWHNQLSEQEYCHRFAKVQQYLHSGDCYQI
NLTQRFSADYKGDEWQAYKTLRQTNAAPFSAFIRLEQHALLSISPERFIQHQLGKVQTKPIKGTMPRDKDPHRDYQLAEQ
LKASEKDRAENLMIVDLLRNDIGKVAAPGSVNVPRLFDVESFPAVHHLVSTITATLQPNLCPTDLLQACFPGGSITGAPK
IRAMEIIEELEPSRRSIYCGSIGYISQDGNMDTSITIRTLLGQRKIDNPDAGGTLYCWAGGGIVADSKVDAEYQESFDKV
SRILPVLSQM
>Mature_490_residues
MNKLAQNAVFSKRLDWNLSTTEVFDYFSDLPWSILLDSADADHVDAKFDVICAEPIATLVTQAQSTIVTRSKDRAPLYML
GNVNLHFEASVTEVSGKPFDVVKQLINEYYPQKKQSPFLFSGGVMGSFSYDLARGIEKLPVIANNDISLPEMNLGCYDWA
LVFDYEIKCWHLVHYLSEQALEELEQRLNALVIAAKPSKLKLTENFALDGQWHNQLSEQEYCHRFAKVQQYLHSGDCYQI
NLTQRFSADYKGDEWQAYKTLRQTNAAPFSAFIRLEQHALLSISPERFIQHQLGKVQTKPIKGTMPRDKDPHRDYQLAEQ
LKASEKDRAENLMIVDLLRNDIGKVAAPGSVNVPRLFDVESFPAVHHLVSTITATLQPNLCPTDLLQACFPGGSITGAPK
IRAMEIIEELEPSRRSIYCGSIGYISQDGNMDTSITIRTLLGQRKIDNPDAGGTLYCWAGGGIVADSKVDAEYQESFDKV
SRILPVLSQM

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=478, Percent_Identity=51.0460251046025, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787518, Length=405, Percent_Identity=29.6296296296296, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786809, Length=211, Percent_Identity=27.0142180094787, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082077, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=375, Percent_Identity=33.0666666666667, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6324361, Length=424, Percent_Identity=26.1792452830189, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 55095; Mature: 55095

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLAQNAVFSKRLDWNLSTTEVFDYFSDLPWSILLDSADADHVDAKFDVICAEPIATLV
CCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHH
TQAQSTIVTRSKDRAPLYMLGNVNLHFEASVTEVSGKPFDVVKQLINEYYPQKKQSPFLF
HHHHHHHEECCCCCCCEEEEECEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
SGGVMGSFSYDLARGIEKLPVIANNDISLPEMNLGCYDWALVFDYEIKCWHLVHYLSEQA
ECCCCCCCHHHHHCCHHHCCEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHH
LEELEQRLNALVIAAKPSKLKLTENFALDGQWHNQLSEQEYCHRFAKVQQYLHSGDCYQI
HHHHHHHHCEEEEEECCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NLTQRFSADYKGDEWQAYKTLRQTNAAPFSAFIRLEQHALLSISPERFIQHQLGKVQTKP
EEHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECHHHHHHHHHCCCCCCC
IKGTMPRDKDPHRDYQLAEQLKASEKDRAENLMIVDLLRNDIGKVAAPGSVNVPRLFDVE
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEHHHHHHHHCCCCCCCCCCCCEEECCC
SFPAVHHLVSTITATLQPNLCPTDLLQACFPGGSITGAPKIRAMEIIEELEPSRRSIYCG
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEC
SIGYISQDGNMDTSITIRTLLGQRKIDNPDAGGTLYCWAGGGIVADSKVDAEYQESFDKV
CCCEEECCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHH
SRILPVLSQM
HHHHHHHHCC
>Mature Secondary Structure
MNKLAQNAVFSKRLDWNLSTTEVFDYFSDLPWSILLDSADADHVDAKFDVICAEPIATLV
CCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHH
TQAQSTIVTRSKDRAPLYMLGNVNLHFEASVTEVSGKPFDVVKQLINEYYPQKKQSPFLF
HHHHHHHEECCCCCCCEEEEECEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
SGGVMGSFSYDLARGIEKLPVIANNDISLPEMNLGCYDWALVFDYEIKCWHLVHYLSEQA
ECCCCCCCHHHHHCCHHHCCEEECCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHH
LEELEQRLNALVIAAKPSKLKLTENFALDGQWHNQLSEQEYCHRFAKVQQYLHSGDCYQI
HHHHHHHHCEEEEEECCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NLTQRFSADYKGDEWQAYKTLRQTNAAPFSAFIRLEQHALLSISPERFIQHQLGKVQTKP
EEHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECHHHHHHHHHCCCCCCC
IKGTMPRDKDPHRDYQLAEQLKASEKDRAENLMIVDLLRNDIGKVAAPGSVNVPRLFDVE
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEHHHHHHHHCCCCCCCCCCCCEEECCC
SFPAVHHLVSTITATLQPNLCPTDLLQACFPGGSITGAPKIRAMEIIEELEPSRRSIYCG
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEC
SIGYISQDGNMDTSITIRTLLGQRKIDNPDAGGTLYCWAGGGIVADSKVDAEYQESFDKV
CCCEEECCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHH
SRILPVLSQM
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]