Click here to switch to the map view.

The map label for this gene is hypD2 [H]

Identifier: 157961846

GI number: 157961846

Start: 2450325

End: 2451443

Strand: Reverse

Name: hypD2 [H]

Synonym: Spea_2025

Alternate gene names: 157961846

Gene position: 2451443-2450325 (Counterclockwise)

Preceding gene: 157961847

Following gene: 157961845

Centisome position: 47.37

GC content: 45.84

Gene sequence:

>1119_bases
ATGATTGGTCTAACAGATCTATACAAGGGCTTTAGGGATCCCAAAGTCATACGCTCCTTAGCTAAAGAGATAGCCACTCA
AGCAAACTTGCTCGACGGTAAGATTAATATAATGGAAGTATGCGGCGGCCATACTCACACCATAATGAAGTACGGTTTAA
ACCAGCTCTTACCAGACAATATCGATTTTATCCATGGGCCGGGCTGTCCTGTTTGTATCATGCCAAAAGAGCGAATCGAT
CATGCCGCCGCACTGGCGAGCATGCCCAATTCCATTTTGGTTACCCTTGGTGACATGATCCGTGTACCAGGATCGAAAGG
AAGCTTGGCACAGCACAGAGCAAGTGGTTGTGATATTCGGCCTATTTACGATCCGCTAGATACCTTACAGATCGCTATCG
ATAATCCTGATAAAACCGTCATTTTCTTCGCGATTGGTTTTGAAACCTCGAGCCCTATGACAGCGGTTCTTATTGACCAA
GCAGAAAAGCGTGATATCAAAAACCTTGTATTTCACATTAACCACGTGCTTGTCCCTCCCGCTATTGATGCCGTTATGGC
CGATCCCAAGGTTAAAGTGAATGCCTTTATTGGACCGTCCCATGTCAGCGTCATTAGTGGTGCGAAAGTCTACCGACCAG
CAGTAAACAACTATAACACTCCAGTGGTCATCTCAGGCTTTGAGCCTGTCGATGTCATGCAGTCAATTTTGATGATTGTA
AAGCAAAAAGTGGCCTCGAAGGCGGAGCTAGAGAATCAGTACAGTCGCTCTGTTTCAGAAGATGGCAACCTTGCCGCCCA
AGAGATGGTAAACCGCTATTTTAAAGTAAGAGATAACTTTCGCTGGCGAGGTCTTGGCCCAATCCCCTCTTCTGCTTTGA
TATTAAGAGATAAATATGCTCATAGAGACGCCGAACGTCTTTTTGCTGAGTTTCTCCCAAGTGAGGAGATTGACGATCAT
AAAGCCTGTCAGTGCGGTGATATTCTTCGTGGTTTATGTAAGCCCAAAGACTGTAAGGTATTTGGGCGTGGCTGTACACC
TGAAACGCCATTAGGCAGTTGTATGGTCAGCTCTGAGGGCGCTTGCAACGCTTACTATCGCTATAACGGAGTATTGTAA

Upstream 100 bases:

>100_bases
GTTTTGTAATGAACAAGATAGATAAAACCGATGCTATGGAGAGTTTAGCGCTCTATCGAGAGATAGTAGAAAAACTCGAA
CTTGAAGAGAAGGAGTCTTA

Downstream 100 bases:

>100_bases
TGAACCAGAATAATTCTCGAAAAATAGTACAACTTAGCCATGGCGGTGGTGGTAAAGAGATGAACCACTTGATTAAAGAT
CTGTTCTTTAAAGCCTTCGA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MIGLTDLYKGFRDPKVIRSLAKEIATQANLLDGKINIMEVCGGHTHTIMKYGLNQLLPDNIDFIHGPGCPVCIMPKERID
HAAALASMPNSILVTLGDMIRVPGSKGSLAQHRASGCDIRPIYDPLDTLQIAIDNPDKTVIFFAIGFETSSPMTAVLIDQ
AEKRDIKNLVFHINHVLVPPAIDAVMADPKVKVNAFIGPSHVSVISGAKVYRPAVNNYNTPVVISGFEPVDVMQSILMIV
KQKVASKAELENQYSRSVSEDGNLAAQEMVNRYFKVRDNFRWRGLGPIPSSALILRDKYAHRDAERLFAEFLPSEEIDDH
KACQCGDILRGLCKPKDCKVFGRGCTPETPLGSCMVSSEGACNAYYRYNGVL

Sequences:

>Translated_372_residues
MIGLTDLYKGFRDPKVIRSLAKEIATQANLLDGKINIMEVCGGHTHTIMKYGLNQLLPDNIDFIHGPGCPVCIMPKERID
HAAALASMPNSILVTLGDMIRVPGSKGSLAQHRASGCDIRPIYDPLDTLQIAIDNPDKTVIFFAIGFETSSPMTAVLIDQ
AEKRDIKNLVFHINHVLVPPAIDAVMADPKVKVNAFIGPSHVSVISGAKVYRPAVNNYNTPVVISGFEPVDVMQSILMIV
KQKVASKAELENQYSRSVSEDGNLAAQEMVNRYFKVRDNFRWRGLGPIPSSALILRDKYAHRDAERLFAEFLPSEEIDDH
KACQCGDILRGLCKPKDCKVFGRGCTPETPLGSCMVSSEGACNAYYRYNGVL
>Mature_372_residues
MIGLTDLYKGFRDPKVIRSLAKEIATQANLLDGKINIMEVCGGHTHTIMKYGLNQLLPDNIDFIHGPGCPVCIMPKERID
HAAALASMPNSILVTLGDMIRVPGSKGSLAQHRASGCDIRPIYDPLDTLQIAIDNPDKTVIFFAIGFETSSPMTAVLIDQ
AEKRDIKNLVFHINHVLVPPAIDAVMADPKVKVNAFIGPSHVSVISGAKVYRPAVNNYNTPVVISGFEPVDVMQSILMIV
KQKVASKAELENQYSRSVSEDGNLAAQEMVNRYFKVRDNFRWRGLGPIPSSALILRDKYAHRDAERLFAEFLPSEEIDDH
KACQCGDILRGLCKPKDCKVFGRGCTPETPLGSCMVSSEGACNAYYRYNGVL

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=364, Percent_Identity=43.6813186813187, Blast_Score=350, Evalue=6e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40886; Mature: 40886

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLTDLYKGFRDPKVIRSLAKEIATQANLLDGKINIMEVCGGHTHTIMKYGLNQLLPDN
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
IDFIHGPGCPVCIMPKERIDHAAALASMPNSILVTLGDMIRVPGSKGSLAQHRASGCDIR
CCEEECCCCCEEECCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCHHHHHCCCCCCC
PIYDPLDTLQIAIDNPDKTVIFFAIGFETSSPMTAVLIDQAEKRDIKNLVFHINHVLVPP
CCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHEECCC
AIDAVMADPKVKVNAFIGPSHVSVISGAKVYRPAVNNYNTPVVISGFEPVDVMQSILMIV
HHHHHHCCCCEEEEEEECCCHHHHHCCCHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
KQKVASKAELENQYSRSVSEDGNLAAQEMVNRYFKVRDNFRWRGLGPIPSSALILRDKYA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEHHHH
HRDAERLFAEFLPSEEIDDHKACQCGDILRGLCKPKDCKVFGRGCTPETPLGSCMVSSEG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
ACNAYYRYNGVL
CCEEEEEECCCC
>Mature Secondary Structure
MIGLTDLYKGFRDPKVIRSLAKEIATQANLLDGKINIMEVCGGHTHTIMKYGLNQLLPDN
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
IDFIHGPGCPVCIMPKERIDHAAALASMPNSILVTLGDMIRVPGSKGSLAQHRASGCDIR
CCEEECCCCCEEECCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCCHHHHHCCCCCCC
PIYDPLDTLQIAIDNPDKTVIFFAIGFETSSPMTAVLIDQAEKRDIKNLVFHINHVLVPP
CCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHEECCC
AIDAVMADPKVKVNAFIGPSHVSVISGAKVYRPAVNNYNTPVVISGFEPVDVMQSILMIV
HHHHHHCCCCEEEEEEECCCHHHHHCCCHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
KQKVASKAELENQYSRSVSEDGNLAAQEMVNRYFKVRDNFRWRGLGPIPSSALILRDKYA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEHHHH
HRDAERLFAEFLPSEEIDDHKACQCGDILRGLCKPKDCKVFGRGCTPETPLGSCMVSSEG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
ACNAYYRYNGVL
CCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]