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The map label for this gene is hypE [H]

Identifier: 157961845

GI number: 157961845

Start: 2449309

End: 2450325

Strand: Reverse

Name: hypE [H]

Synonym: Spea_2024

Alternate gene names: 157961845

Gene position: 2450325-2449309 (Counterclockwise)

Preceding gene: 157961846

Following gene: 157961844

Centisome position: 47.35

GC content: 44.84

Gene sequence:

>1017_bases
ATGAACCAGAATAATTCTCGAAAAATAGTACAACTTAGCCATGGCGGTGGTGGTAAAGAGATGAACCACTTGATTAAAGA
TCTGTTCTTTAAAGCCTTCGATAATCCTATTTTACGCAGCGAAGAAGATGCAGCTGTTTTGCATTTCGACGGTAATCTTG
CCTTTACGACAGACTCGTTTACTGTCTCTCCCCTTTTTTTCCCCGGTGGAGATATTGGCAAGCTATCCATTGCAGGAACC
GTTAACGACTTGGCAATGATGGGGGCTGAGCCACAATATCTCAGCTGCAGTTTCATAATCGAAGAAGGTTTTGAAATTAC
TCACTTAAAAACCATAGTCGAAAGTATGGCCAACGAATTAAAGCAATCGGGAGCACGTATTGTTTGCGGAGATACTAAGG
TCGTTCCTCGTGGTTGTGCCGACGGGATCTTCATTAATACTTCTGGAGTCGGTCGTATTCTGCGAAAAGGAATATCAGTT
AAAAACCTAGCTAGCGATGATGTCATTATTGTATCTCGAGATGTTGGACGACACGGAGCAGCAATCTTAATGGCGAGAGA
AGGGCTAGCACTTGAGTCAGAGCTAACCAGTGATTGCGCGACATTATGGCCAATAGTTGAACAGCTGATAGCGGCAAACA
TCGAAATCCATGCGATGCGTGATGCAACCCGCGGTGGTCTATCTGCAGTACTTAATGAATGGGCCTGTGCATCAAATGTC
GAGATCAATGTAAACGAACAAGCGATCCCAGTATGCGATGAAGTGAGAGGACTTTGCGAGTTATATGGTTTTGAGCCACT
CGATCTCGCCAATGAAGGTACCTTTATTCTTGCAGTACCAAAGGAGAGTGCCGACGCGACATTAGAAATAATGAAACGCT
TTTGTCATTGCGAGCAAGCAGCCGTAATTGGTAACGTAAACGATAACCGCAAAGGAAAAGTTGTACTCAACACGCCTTGG
GGGAGCTCTCGTTATCTAGACTTACCACAAGGCGAGCTGTTACCGAGGATCTGCTAG

Upstream 100 bases:

>100_bases
TATTTGGGCGTGGCTGTACACCTGAAACGCCATTAGGCAGTTGTATGGTCAGCTCTGAGGGCGCTTGCAACGCTTACTAT
CGCTATAACGGAGTATTGTA

Downstream 100 bases:

>100_bases
TGCACGAGTATTCAATTGTTACAGCACTAATTGAAGAGTGCGAACGCCATGCCGCGGCCAATAACGCAAATGAAATTAGC
CGTGTTGAAATCAAACTTGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNQNNSRKIVQLSHGGGGKEMNHLIKDLFFKAFDNPILRSEEDAAVLHFDGNLAFTTDSFTVSPLFFPGGDIGKLSIAGT
VNDLAMMGAEPQYLSCSFIIEEGFEITHLKTIVESMANELKQSGARIVCGDTKVVPRGCADGIFINTSGVGRILRKGISV
KNLASDDVIIVSRDVGRHGAAILMAREGLALESELTSDCATLWPIVEQLIAANIEIHAMRDATRGGLSAVLNEWACASNV
EINVNEQAIPVCDEVRGLCELYGFEPLDLANEGTFILAVPKESADATLEIMKRFCHCEQAAVIGNVNDNRKGKVVLNTPW
GSSRYLDLPQGELLPRIC

Sequences:

>Translated_338_residues
MNQNNSRKIVQLSHGGGGKEMNHLIKDLFFKAFDNPILRSEEDAAVLHFDGNLAFTTDSFTVSPLFFPGGDIGKLSIAGT
VNDLAMMGAEPQYLSCSFIIEEGFEITHLKTIVESMANELKQSGARIVCGDTKVVPRGCADGIFINTSGVGRILRKGISV
KNLASDDVIIVSRDVGRHGAAILMAREGLALESELTSDCATLWPIVEQLIAANIEIHAMRDATRGGLSAVLNEWACASNV
EINVNEQAIPVCDEVRGLCELYGFEPLDLANEGTFILAVPKESADATLEIMKRFCHCEQAAVIGNVNDNRKGKVVLNTPW
GSSRYLDLPQGELLPRIC
>Mature_338_residues
MNQNNSRKIVQLSHGGGGKEMNHLIKDLFFKAFDNPILRSEEDAAVLHFDGNLAFTTDSFTVSPLFFPGGDIGKLSIAGT
VNDLAMMGAEPQYLSCSFIIEEGFEITHLKTIVESMANELKQSGARIVCGDTKVVPRGCADGIFINTSGVGRILRKGISV
KNLASDDVIIVSRDVGRHGAAILMAREGLALESELTSDCATLWPIVEQLIAANIEIHAMRDATRGGLSAVLNEWACASNV
EINVNEQAIPVCDEVRGLCELYGFEPLDLANEGTFILAVPKESADATLEIMKRFCHCEQAAVIGNVNDNRKGKVVLNTPW
GSSRYLDLPQGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=48.0712166172107, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36605; Mature: 36605

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQNNSRKIVQLSHGGGGKEMNHLIKDLFFKAFDNPILRSEEDAAVLHFDGNLAFTTDSF
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCE
TVSPLFFPGGDIGKLSIAGTVNDLAMMGAEPQYLSCSFIIEEGFEITHLKTIVESMANEL
EEEEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPRGCADGIFINTSGVGRILRKGISVKNLASDDVIIVSRDVGRHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCE
AILMAREGLALESELTSDCATLWPIVEQLIAANIEIHAMRDATRGGLSAVLNEWACASNV
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCC
EINVNEQAIPVCDEVRGLCELYGFEPLDLANEGTFILAVPKESADATLEIMKRFCHCEQA
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
AVIGNVNDNRKGKVVLNTPWGSSRYLDLPQGELLPRIC
EEEECCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNQNNSRKIVQLSHGGGGKEMNHLIKDLFFKAFDNPILRSEEDAAVLHFDGNLAFTTDSF
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCE
TVSPLFFPGGDIGKLSIAGTVNDLAMMGAEPQYLSCSFIIEEGFEITHLKTIVESMANEL
EEEEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPRGCADGIFINTSGVGRILRKGISVKNLASDDVIIVSRDVGRHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCE
AILMAREGLALESELTSDCATLWPIVEQLIAANIEIHAMRDATRGGLSAVLNEWACASNV
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCC
EINVNEQAIPVCDEVRGLCELYGFEPLDLANEGTFILAVPKESADATLEIMKRFCHCEQA
EEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
AVIGNVNDNRKGKVVLNTPWGSSRYLDLPQGELLPRIC
EEEECCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]