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The map label for this gene is fabA [H]

Identifier: 157961774

GI number: 157961774

Start: 2373668

End: 2374183

Strand: Reverse

Name: fabA [H]

Synonym: Spea_1951

Alternate gene names: 157961774

Gene position: 2374183-2373668 (Counterclockwise)

Preceding gene: 157961775

Following gene: 157961768

Centisome position: 45.88

GC content: 43.99

Gene sequence:

>516_bases
ATGAGTAACGCAAATAGTTTTACCAAAGAAGATCTTATTGCCTGTGGACTGGGCAAATTATTCGGACCTAATTCTCCGAG
ACTGCCAAAAGACAACATGTTAATGATCGACCGTGTACTAAAAATTAACGCGGATGGTGGTGAGTACGGTAAAGGTGAGA
TTGTTGCAGAACTCGATATTAATCCAGATCTATGGTTTTTTGACTGTCATTTCGCCACTGACCCTGTTATGCCTGGCTGC
TTAGGTCTTGATGCCATGTGGCAGTTAGTCGGCTTCTTCCTCGGATGGGAAGGCGCTGAGGGCAAAGGAAGAGCGCTAGG
TGTAGGTGAAGTAAAGTTTACAGGTCAAGTATTGCCTGAAGCTAAAAAAGTCACCTACAAGCTGACCATTAAGCGTAAAG
TTTACCGTAAGTTGGTTATGGGTATTGCTGATGCCACGATGGAAGTCGATGGCCGTGAAATCTATAGCGCGAAAGATCTT
AAGGTCGGTATTTTTACCGATACGACTAGCTTCTAA

Upstream 100 bases:

>100_bases
AGACTCGTCGATAAATTGAGATTTTTTAGCTGATCGGAGTTGTTTAGCGTACACGTGTTCGCTAATCTTGGCAGCTCAAA
TTGCTGGAGTATCAAAAATA

Downstream 100 bases:

>100_bases
TAGCTAATTATTGAGATAGCTATACCGCAATAAAAATGCCCTCTTTGATAGAGGGCAAAATTGTTTCTCAATGATTGTTT
ACTTCAAAATAATTCTTAGA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINADGGEYGKGEIVAELDINPDLWFFDCHFATDPVMPGC
LGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPEAKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDL
KVGIFTDTTSF

Sequences:

>Translated_171_residues
MSNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINADGGEYGKGEIVAELDINPDLWFFDCHFATDPVMPGC
LGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPEAKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDL
KVGIFTDTTSF
>Mature_170_residues
SNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINADGGEYGKGEIVAELDINPDLWFFDCHFATDPVMPGCL
GLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPEAKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDLK
VGIFTDTTSF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=167, Percent_Identity=69.4610778443114, Blast_Score=245, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18805; Mature: 18674

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINADGGEYGKGEIVAELDI
CCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFDCHFATDPVMPGCLGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPE
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEECCCCCCC
AKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDLKVGIFTDTTSF
CEEEEEEEEEHHHHHHHHHHHHHCCEEEECCCEEECCCCEEEEEEECCCCC
>Mature Secondary Structure 
SNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINADGGEYGKGEIVAELDI
CCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPDLWFFDCHFATDPVMPGCLGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPE
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEECCCCCCC
AKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDLKVGIFTDTTSF
CEEEEEEEEEHHHHHHHHHHHHHCCEEEECCCEEECCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA