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The map label for this gene is dcp [H]

Identifier: 157961681

GI number: 157961681

Start: 2257913

End: 2260102

Strand: Reverse

Name: dcp [H]

Synonym: Spea_1857

Alternate gene names: 157961681

Gene position: 2260102-2257913 (Counterclockwise)

Preceding gene: 157961682

Following gene: 157961678

Centisome position: 43.68

GC content: 46.53

Gene sequence:

>2190_bases
ATGAAGGGATTAACCCTCAAACCAATCGTATCAGCAGTCGCTTTAGCATTAGCTCTTAGTGCATGTGGTGCTTCAAATAT
AAGCAAAGATACCAGTACTGAAACACAAATCGCACCCAAGGTCGTTGCCCAGCAAATCATCGACAACAATGCCAGCAACC
CTTTCTTCAAGCCTTACGATACCTACTTTGGTATTCCTGATTTTGCCAAAATCAAACCTGAACACTACCTACCCGCTTTC
AAAGCCGGTATTGCTCAGCATAAAGCTGAAATTCAAGCCATTATCGATAACCCTGATGCACCTACTTTCGCTAATACCAT
AGAAGCGATGGAGTACTCGGGTAACTTAACCACCAAAGTCGCCAGCGTGTTTTATAACCTAACGGGTGCTGACACTAACG
AGCAGCTACAAGTTATCTCTAAAAAAGTGGCACCTATGCTCTCTTCTGCCAACGATGACATTTTGTTGAACGATGCTCTT
TTCCAAAAAGTGAAAGCGGTTTATAACCATCGCGATTCGCTATCTCTTAACGTTGCTCAGGCAAAGCTGCTCGAAGACAC
CTATAAATCATTTACCCGCGGCGGTGCCAACTTAAGCGAAGCGGACAAAACCAAGCTACGTGGCTTGAATGAACAAATTG
GTAAGCTTAGCCTGGAGTTTGGTGACAACCTGCTGGCTGAAACTAACGCATTTGAGCTAGTAATCGATAGCAAAGCTGAC
TTAGCGGGTCTGCCTGAAGACGTAATTAACACTGCGGCGCAAACAGCAGTTAAACGTGGCCATGAAGGCAAATGGGTGTT
CACCACCTCTCGCCCATCGATTACGCCATTTTTGACCTATGCAGATAATCGCGATCTGCGTGAAGTCCTGTACAAGGGCT
ACGTTGAGCGCGGTAACAATGACAATGCCAACGACAACAAGAAAATCTTAGCTAAAATGGCTGCGCTACGTGCTGAGCGC
GCACAGCTGATGGGTTACAAAACTCACGCGCATTTCGTACTCGAAGAGCGTACAGCTCAAACCCCTGAAAATGTATATGA
GTTACTCAACAAAGTATGGCCTGCAGCACTAGCACAAGCGGAATCTGAAGTTGCCGATATGCAGACGCTTATCAACCAAG
AAGGCGGGGAGTTCAAACTTGCTGGCTGGGATTGGTGGTATTACTCAGATAAAATTCGTGTCGCTAAGTACAGCTTTAAT
GAGCAGCAAACACGCCCTTACTTTTCACTAGAAAACACCCTTCAAGGTGTGTTCTACACGGCTAATCGCCTGTTTGGTAT
TACCGTCAAAGAGCGAACCGACTTACCTAAGTACAATGAAGAAGTACGTACTTGGGAAGTTTACGACAAGAATGGTGAGC
TAATGGCCATCTTCTTAGGAGATTACTTCGTCCGCGACAGCAAGCGTGGCGGCGCTTGGATGAACTCTTATCGCCAGCAG
TACAACATGGATGGTGTCGATTCTAAGCCTATTATTGTTAACGTACTTAACTACCCTCGCCCTGTGGGTGATGAGCCAGC
ACTGCTGACATTTGACGAAGCAAGTACACTGTTCCATGAGTTTGGTCATGCACTGCATGGTATGTTGTCTGATGTTGAGT
ATCGCTCACAGGCGGGGACATCTGTACCACGTGACTACGTTGAGTTTCCATCTCAAGTGATGGAAAACTGGATGACACAA
CCTGAGGTGTTAGCGCAATTTGCCAAGCACTACAAAACCGGCGAAGTGATCCCTCAAGAGCTGGTTAAGAAAATCCAAGC
GGCAAGTAAGTTCAACCAAGGTTTTGCAACGGTTGAATATATGGCGGCAACTAAGCTGGATCTTGACTGGCACACAGTCA
CCGACTTTATGCCAAAAGATGCGGCTAAGTTTGAAGCCGAGTCGCTGAACAAGATGGGGCTTATCTCTGAGATCGCGCCG
CGTTATCGCAGTACTTATTTCTCACATATCTTCTCGGGTGGATACTCTGCAGGCTACTACAGCTACATCTGGTCTGATAT
TTTAGGCGCCGATGCATTTGAAGCCTTTAAAGAGAATGGTATTTTCGATAAAGCCACTGCCGATGCCTTTAGAAACAACA
TTCTGTCTCAAGGCGGCAGCGAGGATCCGATGCAACTTTACAAGCAATTCCGCGGTAAAGAAGCCGGTATTGACCCGCTA
CTTCGCAGCCGTGGCTTATTGGCTAAGTAG

Upstream 100 bases:

>100_bases
TTTAATAGATTTGATACCTTTATGCGTGGTACTTAAAGAGGTTAACGTTAGTGTAATTAAATTGACGAGAATTAAAACAA
GCATAATCGGGGATATAAAT

Downstream 100 bases:

>100_bases
TATTGCTAAAACTGAGTTACAAACGCGAAAAGGCTCCTAAAAGGAGCCTTTTTATCTATTAACTGATGAGGTTAACTCAC
AGGAGCTAACCACTGATAAA

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MKGLTLKPIVSAVALALALSACGASNISKDTSTETQIAPKVVAQQIIDNNASNPFFKPYDTYFGIPDFAKIKPEHYLPAF
KAGIAQHKAEIQAIIDNPDAPTFANTIEAMEYSGNLTTKVASVFYNLTGADTNEQLQVISKKVAPMLSSANDDILLNDAL
FQKVKAVYNHRDSLSLNVAQAKLLEDTYKSFTRGGANLSEADKTKLRGLNEQIGKLSLEFGDNLLAETNAFELVIDSKAD
LAGLPEDVINTAAQTAVKRGHEGKWVFTTSRPSITPFLTYADNRDLREVLYKGYVERGNNDNANDNKKILAKMAALRAER
AQLMGYKTHAHFVLEERTAQTPENVYELLNKVWPAALAQAESEVADMQTLINQEGGEFKLAGWDWWYYSDKIRVAKYSFN
EQQTRPYFSLENTLQGVFYTANRLFGITVKERTDLPKYNEEVRTWEVYDKNGELMAIFLGDYFVRDSKRGGAWMNSYRQQ
YNMDGVDSKPIIVNVLNYPRPVGDEPALLTFDEASTLFHEFGHALHGMLSDVEYRSQAGTSVPRDYVEFPSQVMENWMTQ
PEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTVTDFMPKDAAKFEAESLNKMGLISEIAP
RYRSTYFSHIFSGGYSAGYYSYIWSDILGADAFEAFKENGIFDKATADAFRNNILSQGGSEDPMQLYKQFRGKEAGIDPL
LRSRGLLAK

Sequences:

>Translated_729_residues
MKGLTLKPIVSAVALALALSACGASNISKDTSTETQIAPKVVAQQIIDNNASNPFFKPYDTYFGIPDFAKIKPEHYLPAF
KAGIAQHKAEIQAIIDNPDAPTFANTIEAMEYSGNLTTKVASVFYNLTGADTNEQLQVISKKVAPMLSSANDDILLNDAL
FQKVKAVYNHRDSLSLNVAQAKLLEDTYKSFTRGGANLSEADKTKLRGLNEQIGKLSLEFGDNLLAETNAFELVIDSKAD
LAGLPEDVINTAAQTAVKRGHEGKWVFTTSRPSITPFLTYADNRDLREVLYKGYVERGNNDNANDNKKILAKMAALRAER
AQLMGYKTHAHFVLEERTAQTPENVYELLNKVWPAALAQAESEVADMQTLINQEGGEFKLAGWDWWYYSDKIRVAKYSFN
EQQTRPYFSLENTLQGVFYTANRLFGITVKERTDLPKYNEEVRTWEVYDKNGELMAIFLGDYFVRDSKRGGAWMNSYRQQ
YNMDGVDSKPIIVNVLNYPRPVGDEPALLTFDEASTLFHEFGHALHGMLSDVEYRSQAGTSVPRDYVEFPSQVMENWMTQ
PEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTVTDFMPKDAAKFEAESLNKMGLISEIAP
RYRSTYFSHIFSGGYSAGYYSYIWSDILGADAFEAFKENGIFDKATADAFRNNILSQGGSEDPMQLYKQFRGKEAGIDPL
LRSRGLLAK
>Mature_729_residues
MKGLTLKPIVSAVALALALSACGASNISKDTSTETQIAPKVVAQQIIDNNASNPFFKPYDTYFGIPDFAKIKPEHYLPAF
KAGIAQHKAEIQAIIDNPDAPTFANTIEAMEYSGNLTTKVASVFYNLTGADTNEQLQVISKKVAPMLSSANDDILLNDAL
FQKVKAVYNHRDSLSLNVAQAKLLEDTYKSFTRGGANLSEADKTKLRGLNEQIGKLSLEFGDNLLAETNAFELVIDSKAD
LAGLPEDVINTAAQTAVKRGHEGKWVFTTSRPSITPFLTYADNRDLREVLYKGYVERGNNDNANDNKKILAKMAALRAER
AQLMGYKTHAHFVLEERTAQTPENVYELLNKVWPAALAQAESEVADMQTLINQEGGEFKLAGWDWWYYSDKIRVAKYSFN
EQQTRPYFSLENTLQGVFYTANRLFGITVKERTDLPKYNEEVRTWEVYDKNGELMAIFLGDYFVRDSKRGGAWMNSYRQQ
YNMDGVDSKPIIVNVLNYPRPVGDEPALLTFDEASTLFHEFGHALHGMLSDVEYRSQAGTSVPRDYVEFPSQVMENWMTQ
PEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTVTDFMPKDAAKFEAESLNKMGLISEIAP
RYRSTYFSHIFSGGYSAGYYSYIWSDILGADAFEAFKENGIFDKATADAFRNNILSQGGSEDPMQLYKQFRGKEAGIDPL
LRSRGLLAK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=593, Percent_Identity=28.3305227655987, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI14149738, Length=606, Percent_Identity=28.7128712871287, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI156105687, Length=679, Percent_Identity=26.3622974963181, Blast_Score=173, Evalue=5e-43,
Organism=Escherichia coli, GI1787819, Length=677, Percent_Identity=41.2112259970458, Blast_Score=543, Evalue=1e-155,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=34.6938775510204, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71999758, Length=640, Percent_Identity=21.40625, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32565901, Length=604, Percent_Identity=22.0198675496689, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319793, Length=652, Percent_Identity=25.6134969325153, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6322715, Length=440, Percent_Identity=25.2272727272727, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356111, Length=695, Percent_Identity=22.3021582733813, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI20129717, Length=585, Percent_Identity=24.2735042735043, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 81689; Mature: 81689

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLTLKPIVSAVALALALSACGASNISKDTSTETQIAPKVVAQQIIDNNASNPFFKPYD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
TYFGIPDFAKIKPEHYLPAFKAGIAQHKAEIQAIIDNPDAPTFANTIEAMEYSGNLTTKV
HHCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHH
ASVFYNLTGADTNEQLQVISKKVAPMLSSANDDILLNDALFQKVKAVYNHRDSLSLNVAQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEHHHH
AKLLEDTYKSFTRGGANLSEADKTKLRGLNEQIGKLSLEFGDNLLAETNAFELVIDSKAD
HHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHEEEHHHCCCHHCCCCCEEEEEECCCC
LAGLPEDVINTAAQTAVKRGHEGKWVFTTSRPSITPFLTYADNRDLREVLYKGYVERGNN
CCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
DNANDNKKILAKMAALRAERAQLMGYKTHAHFVLEERTAQTPENVYELLNKVWPAALAQA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
ESEVADMQTLINQEGGEFKLAGWDWWYYSDKIRVAKYSFNEQQTRPYFSLENTLQGVFYT
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCEEEEEEECCCCHHCCCCEEHHHHHHHHHEE
ANRLFGITVKERTDLPKYNEEVRTWEVYDKNGELMAIFLGDYFVRDSKRGGAWMNSYRQQ
CCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHCCCCCCHHHHHHHHH
YNMDGVDSKPIIVNVLNYPRPVGDEPALLTFDEASTLFHEFGHALHGMLSDVEYRSQAGT
CCCCCCCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVPRDYVEFPSQVMENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
MAATKLDLDWHTVTDFMPKDAAKFEAESLNKMGLISEIAPRYRSTYFSHIFSGGYSAGYY
HHHHEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SYIWSDILGADAFEAFKENGIFDKATADAFRNNILSQGGSEDPMQLYKQFRGKEAGIDPL
HHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHH
LRSRGLLAK
HHCCCCCCC
>Mature Secondary Structure
MKGLTLKPIVSAVALALALSACGASNISKDTSTETQIAPKVVAQQIIDNNASNPFFKPYD
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
TYFGIPDFAKIKPEHYLPAFKAGIAQHKAEIQAIIDNPDAPTFANTIEAMEYSGNLTTKV
HHCCCCCHHHCCCHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHH
ASVFYNLTGADTNEQLQVISKKVAPMLSSANDDILLNDALFQKVKAVYNHRDSLSLNVAQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCCCCCEEHHHH
AKLLEDTYKSFTRGGANLSEADKTKLRGLNEQIGKLSLEFGDNLLAETNAFELVIDSKAD
HHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHEEEHHHCCCHHCCCCCEEEEEECCCC
LAGLPEDVINTAAQTAVKRGHEGKWVFTTSRPSITPFLTYADNRDLREVLYKGYVERGNN
CCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
DNANDNKKILAKMAALRAERAQLMGYKTHAHFVLEERTAQTPENVYELLNKVWPAALAQA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
ESEVADMQTLINQEGGEFKLAGWDWWYYSDKIRVAKYSFNEQQTRPYFSLENTLQGVFYT
HHHHHHHHHHHCCCCCCEEEEEEEEEEECCEEEEEEECCCCHHCCCCEEHHHHHHHHHEE
ANRLFGITVKERTDLPKYNEEVRTWEVYDKNGELMAIFLGDYFVRDSKRGGAWMNSYRQQ
CCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHHHCCCCCCHHHHHHHHH
YNMDGVDSKPIIVNVLNYPRPVGDEPALLTFDEASTLFHEFGHALHGMLSDVEYRSQAGT
CCCCCCCCCCEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVPRDYVEFPSQVMENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
MAATKLDLDWHTVTDFMPKDAAKFEAESLNKMGLISEIAPRYRSTYFSHIFSGGYSAGYY
HHHHEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SYIWSDILGADAFEAFKENGIFDKATADAFRNNILSQGGSEDPMQLYKQFRGKEAGIDPL
HHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHH
LRSRGLLAK
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]