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The map label for this gene is zraR [H]

Identifier: 157961600

GI number: 157961600

Start: 2162881

End: 2164251

Strand: Reverse

Name: zraR [H]

Synonym: Spea_1776

Alternate gene names: 157961600

Gene position: 2164251-2162881 (Counterclockwise)

Preceding gene: 157961601

Following gene: 157961599

Centisome position: 41.82

GC content: 44.86

Gene sequence:

>1371_bases
GTGAATAAATTTAAAAATAAGAGGCCCATTGCTTGTAGAGAACTCCTTGTGCTTGACCTTGCTGGTGAGTTTTTTGGCTA
TGATAAAGAACTCAAACCGTTTCGTTGGCACTGCATTGTCGCCGATACACTTTCCTGTGCGAAAAAGGCAGCGCAAGCAT
ACAATTTTCAGGTTGCTGTAGCAGTCATATCCAAAGGAATTCAGCATCAGGTTCTAAGTTGTATCAATGAGCTCAATCAG
CGTCAACAGAACATTATCTGGGTAGCCGTATTAATCGATATCGACGCAGTAGATGTAAAGTTCACTTCTCGCCTACCCTA
CTATTTTACCGACTATCACCACCTTCCCGTCGACTGGAACCATCTTAACCAGACTCTTGGGCATGCTTATGGCATGGCAC
TGTTAAAACAGAAAGAGCAAAAGGGTTGCACTGAGTTCGGCCAAAAAACACCATTATTGGGTGACTCTCGTTCCATCAAC
AATTTAAGAAGCAACATAACCAAAGTAGCCACATCAGATGAGGCCGTGCTGATCAGTGGCGAAACCGGTACGGGTAAAGG
ACTGTGTGCACATTTAATTCATAATCAGTCAAGGCGAAAAATTGGTCCCTTCATCACTATCAACTGTGGAGCCTTACCTC
AAAGCTTGATCCACTCTGAACTCTTTGGCCACGAAAAAGGCGCCTTTACTGGCGCCGACAAACAATACATAGGCCATATA
GAAAGAGCCAATAAAGGTACCCTGTTTTTAGATGAGATAGGTGATCTTACATTAGAGTCTCAAGTGAACCTGCTACAATT
TCTCGAAGAGCATATTATCGAGCGCCTCGGCGGCAGCAGGAACATAGCCATTGATTGTCGAATAATCTTCGCTTCCCATG
TTAATCTTGAAACCGCTGTCGAAGAGGGGCGCTTTCGTGAAGATCTCTATTATCGCATCAATATACTGCACCTACACGCA
CCGAGTCTTAGGCAGCATAAAGAGGACATTCCGCTGCTCGCGAATGAGTACCTTAATCTGTTCAGTCCCGAACATCACAA
ATACACCCTGACCCCAAAAGCACTGGATACCATGCTCGATTATGAATGGCCTGGCAATGTGAGGGAACTCAAGAACCGCA
TACATAGAGCCATTATCATGGCGAGTAGCGATCAATTAACTGCAGCGGATTTAGGGATCAAAATCACCAATATTAACCCG
GATGAACACGATGTGGTTGACTTAGCTCAGCATAGGGTGGTGATCGATACCGAGCTACTACTCGATGCCATCAAACGCAA
TAACCACAATATTTCGGCTGCGGCGCGCGAGCTCAAGATCTCCAGAACCACCTTCTATCGTCTGATCAAGAAATGCAAAA
TTAAACTCTAG

Upstream 100 bases:

>100_bases
CCTACCTTTCGACTTGCGTTCCGCCAGATCCTACCTAAAATTTAAACATCGATAGTTAGCCATTGAGGGCGCCGACACAG
AGTTTCTCTAAAGGAGAACC

Downstream 100 bases:

>100_bases
CGATGGCTGTTCGAATCCACTTGAATAGTCGAGGACCCCACAATGTTAATATATAAGCGCCTGTTTATAGCGTTAATGCT
GACACCACTGTTTATCACAG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNKFKNKRPIACRELLVLDLAGEFFGYDKELKPFRWHCIVADTLSCAKKAAQAYNFQVAVAVISKGIQHQVLSCINELNQ
RQQNIIWVAVLIDIDAVDVKFTSRLPYYFTDYHHLPVDWNHLNQTLGHAYGMALLKQKEQKGCTEFGQKTPLLGDSRSIN
NLRSNITKVATSDEAVLISGETGTGKGLCAHLIHNQSRRKIGPFITINCGALPQSLIHSELFGHEKGAFTGADKQYIGHI
ERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIERLGGSRNIAIDCRIIFASHVNLETAVEEGRFREDLYYRINILHLHA
PSLRQHKEDIPLLANEYLNLFSPEHHKYTLTPKALDTMLDYEWPGNVRELKNRIHRAIIMASSDQLTAADLGIKITNINP
DEHDVVDLAQHRVVIDTELLLDAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL

Sequences:

>Translated_456_residues
MNKFKNKRPIACRELLVLDLAGEFFGYDKELKPFRWHCIVADTLSCAKKAAQAYNFQVAVAVISKGIQHQVLSCINELNQ
RQQNIIWVAVLIDIDAVDVKFTSRLPYYFTDYHHLPVDWNHLNQTLGHAYGMALLKQKEQKGCTEFGQKTPLLGDSRSIN
NLRSNITKVATSDEAVLISGETGTGKGLCAHLIHNQSRRKIGPFITINCGALPQSLIHSELFGHEKGAFTGADKQYIGHI
ERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIERLGGSRNIAIDCRIIFASHVNLETAVEEGRFREDLYYRINILHLHA
PSLRQHKEDIPLLANEYLNLFSPEHHKYTLTPKALDTMLDYEWPGNVRELKNRIHRAIIMASSDQLTAADLGIKITNINP
DEHDVVDLAQHRVVIDTELLLDAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL
>Mature_456_residues
MNKFKNKRPIACRELLVLDLAGEFFGYDKELKPFRWHCIVADTLSCAKKAAQAYNFQVAVAVISKGIQHQVLSCINELNQ
RQQNIIWVAVLIDIDAVDVKFTSRLPYYFTDYHHLPVDWNHLNQTLGHAYGMALLKQKEQKGCTEFGQKTPLLGDSRSIN
NLRSNITKVATSDEAVLISGETGTGKGLCAHLIHNQSRRKIGPFITINCGALPQSLIHSELFGHEKGAFTGADKQYIGHI
ERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIERLGGSRNIAIDCRIIFASHVNLETAVEEGRFREDLYYRINILHLHA
PSLRQHKEDIPLLANEYLNLFSPEHHKYTLTPKALDTMLDYEWPGNVRELKNRIHRAIIMASSDQLTAADLGIKITNINP
DEHDVVDLAQHRVVIDTELLLDAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=339, Percent_Identity=41.5929203539823, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1788550, Length=351, Percent_Identity=40.1709401709402, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=47.6394849785408, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=39.622641509434, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1790299, Length=346, Percent_Identity=35.5491329479769, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1788905, Length=285, Percent_Identity=41.7543859649123, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=38.006230529595, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1786524, Length=317, Percent_Identity=39.7476340694006, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=36.9905956112853, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=36.9565217391304, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1787583, Length=228, Percent_Identity=39.4736842105263, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789828, Length=317, Percent_Identity=35.0157728706625, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=29.1095890410959, Blast_Score=128, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51777; Mature: 51777

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFKNKRPIACRELLVLDLAGEFFGYDKELKPFRWHCIVADTLSCAKKAAQAYNFQVAV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEH
AVISKGIQHQVLSCINELNQRQQNIIWVAVLIDIDAVDVKFTSRLPYYFTDYHHLPVDWN
HHHHCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCEEEEEEECCCCEEECCCEECCCCHH
HLNQTLGHAYGMALLKQKEQKGCTEFGQKTPLLGDSRSINNLRSNITKVATSDEAVLISG
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEC
ETGTGKGLCAHLIHNQSRRKIGPFITINCGALPQSLIHSELFGHEKGAFTGADKQYIGHI
CCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
ERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIERLGGSRNIAIDCRIIFASHVNLETAV
HCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHH
EEGRFREDLYYRINILHLHAPSLRQHKEDIPLLANEYLNLFSPEHHKYTLTPKALDTMLD
HCCCCCCCEEEEEEEEEEECCHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHC
YEWPGNVRELKNRIHRAIIMASSDQLTAADLGIKITNINPDEHDVVDLAQHRVVIDTELL
CCCCCCHHHHHHHHHHEEEEECCCCEEEECCCEEEEECCCCHHHHHHHHHCEEEEEHHHH
LDAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKFKNKRPIACRELLVLDLAGEFFGYDKELKPFRWHCIVADTLSCAKKAAQAYNFQVAV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEH
AVISKGIQHQVLSCINELNQRQQNIIWVAVLIDIDAVDVKFTSRLPYYFTDYHHLPVDWN
HHHHCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCEEEEEEECCCCEEECCCEECCCCHH
HLNQTLGHAYGMALLKQKEQKGCTEFGQKTPLLGDSRSINNLRSNITKVATSDEAVLISG
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEC
ETGTGKGLCAHLIHNQSRRKIGPFITINCGALPQSLIHSELFGHEKGAFTGADKQYIGHI
CCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
ERANKGTLFLDEIGDLTLESQVNLLQFLEEHIIERLGGSRNIAIDCRIIFASHVNLETAV
HCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHH
EEGRFREDLYYRINILHLHAPSLRQHKEDIPLLANEYLNLFSPEHHKYTLTPKALDTMLD
HCCCCCCCEEEEEEEEEEECCHHHHHHCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHC
YEWPGNVRELKNRIHRAIIMASSDQLTAADLGIKITNINPDEHDVVDLAQHRVVIDTELL
CCCCCCHHHHHHHHHHEEEEECCCCEEEECCCEEEEECCCCHHHHHHHHHCEEEEEHHHH
LDAIKRNNHNISAAARELKISRTTFYRLIKKCKIKL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]