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The map label for this gene is nreC [H]

Identifier: 157961557

GI number: 157961557

Start: 2108502

End: 2109134

Strand: Reverse

Name: nreC [H]

Synonym: Spea_1733

Alternate gene names: 157961557

Gene position: 2109134-2108502 (Counterclockwise)

Preceding gene: 157961558

Following gene: 157961556

Centisome position: 40.76

GC content: 40.44

Gene sequence:

>633_bases
ATGAATCATGTACAGTTCGAGAAGGATGAACAATTAATTATGCCCACCATTATCATTGCAGATGATCACCAGATAGTCAG
TGAAGGCATCGCAAGGCTTGTTGAAAAAAACTATCAGGTTCAATCAATTACCACCAATGCAGAAGAGTTAATTCAAGCTG
CTAAACAATTTCAACCCGATATCATCATCACAGATATTTCAATGCCAGGTATGCAGCTAAACCAAACACTTGGCTTGCTA
AAACGTACATGTAAAGAAGCAAAGATCATCTGCCTCACCATGCACGATGAAGCTGAAATCCTACAGGCTGCATTCGAATA
TGGTGCTGATGGCTACATAGTGAAACATCAAGCGGGTTTTGAGCTACTACAGGCACTCGAAACCGTACTGGCTGGAAAGC
AATATGTCTCCGCAGAATTACAGGAAAAGTTCAACCAAAAAACAGTGCTAACAGCAAGACAGTTGGATATTTTGAAGCTT
TTGGCAAAAGGCATGTCTGCAAAGAAAATTGCACTCTCACTCAATATTTCCGCCAAAACCGTTGAGTACCATAAATATAA
GATGATTGAGCAGTTAGATTTAGACAATGCCTCATCGCTTGTGGCCTACGCTCATAGCCGAAATCTAATTTAG

Upstream 100 bases:

>100_bases
GCATACTAAATATATAATTGATTTTAATAAGAATGATTTTAATAAGAATGATTTTAATAAGAATGATTTAAATAAGAGTG
ATATTAATAAGAGTGATAGG

Downstream 100 bases:

>100_bases
CCTCAGACATTAGGAGACTTCCTAGTCGATCCCTTGCTAGCTTGAAGAGATAATGGGACCCAATAGAGGAGTTTCTATAT
GTCATCACAAGCTACATACC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNHVQFEKDEQLIMPTIIIADDHQIVSEGIARLVEKNYQVQSITTNAEELIQAAKQFQPDIIITDISMPGMQLNQTLGLL
KRTCKEAKIICLTMHDEAEILQAAFEYGADGYIVKHQAGFELLQALETVLAGKQYVSAELQEKFNQKTVLTARQLDILKL
LAKGMSAKKIALSLNISAKTVEYHKYKMIEQLDLDNASSLVAYAHSRNLI

Sequences:

>Translated_210_residues
MNHVQFEKDEQLIMPTIIIADDHQIVSEGIARLVEKNYQVQSITTNAEELIQAAKQFQPDIIITDISMPGMQLNQTLGLL
KRTCKEAKIICLTMHDEAEILQAAFEYGADGYIVKHQAGFELLQALETVLAGKQYVSAELQEKFNQKTVLTARQLDILKL
LAKGMSAKKIALSLNISAKTVEYHKYKMIEQLDLDNASSLVAYAHSRNLI
>Mature_210_residues
MNHVQFEKDEQLIMPTIIIADDHQIVSEGIARLVEKNYQVQSITTNAEELIQAAKQFQPDIIITDISMPGMQLNQTLGLL
KRTCKEAKIICLTMHDEAEILQAAFEYGADGYIVKHQAGFELLQALETVLAGKQYVSAELQEKFNQKTVLTARQLDILKL
LAKGMSAKKIALSLNISAKTVEYHKYKMIEQLDLDNASSLVAYAHSRNLI

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=194, Percent_Identity=28.3505154639175, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=32.3232323232323, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790102, Length=187, Percent_Identity=32.0855614973262, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=32.7868852459016, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=30.0970873786408, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=24.8756218905473, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23575; Mature: 23575

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVQFEKDEQLIMPTIIIADDHQIVSEGIARLVEKNYQVQSITTNAEELIQAAKQFQPD
CCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCC
IIITDISMPGMQLNQTLGLLKRTCKEAKIICLTMHDEAEILQAAFEYGADGYIVKHQAGF
EEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEHHHH
ELLQALETVLAGKQYVSAELQEKFNQKTVLTARQLDILKLLAKGMSAKKIALSLNISAKT
HHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHH
VEYHKYKMIEQLDLDNASSLVAYAHSRNLI
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MNHVQFEKDEQLIMPTIIIADDHQIVSEGIARLVEKNYQVQSITTNAEELIQAAKQFQPD
CCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCC
IIITDISMPGMQLNQTLGLLKRTCKEAKIICLTMHDEAEILQAAFEYGADGYIVKHQAGF
EEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEHHHH
ELLQALETVLAGKQYVSAELQEKFNQKTVLTARQLDILKLLAKGMSAKKIALSLNISAKT
HHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHH
VEYHKYKMIEQLDLDNASSLVAYAHSRNLI
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA